Search for Cheap Deals onHotels in Southern Minnesota
Choose from 1245 Southern Minnesota Hotel Deals

Med City Inn & Suites - Mayo Clinic Area
"Old place. Rooms were decent and show some updating. Common areas real run down. Hot tub was non-operational and that was a big reason why I booked the stay."
Reviewed on Nov 11, 2026

Kahler Grand Hotel
"Location and staff are wonderful"
Reviewed on Nov 13, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
"I love the swimming pool"
Reviewed on Nov 13, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
"Breakfast was good simple selections. Nice that they had fruit and yougart not everyone enjoys eggs. Room was clean. Beds fairly comfortable. Ice machines did not have ice. Food was with in walking distance to restaurant/bar connected."
Reviewed on Nov 13, 2026

Kahler Inn and Suites - Mayo Clinic Area
"Very convenient to Mayo Clinic using subway access from hotel. No need to walk outside."
Reviewed on Nov 13, 2026

Express Suites Riverport Inn & Suites
"Very cute place with fresh cookies for guests and bar/restaurant in the building. Clean and rooms and friendly staff."
Reviewed on Nov 13, 2026

Brentwood Inn & Suites

Hyatt House Rochester/Mayo Clinic Area
"Clean and nice hotel. Excellent breakfast."
Reviewed on Nov 13, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
"👍🏻"
Reviewed on Nov 13, 2026

AmericInn by Wyndham Mankato Event Center

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
"Nice place!"
Reviewed on Nov 10, 2026
Find cheap hotels in Southern Minnesota
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Frequently Asked Questions About Southern Minnesota hotels
Where can I find the best last-minute travel deals?
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