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Hotels in Southern Minnesota

Choose from 891 Southern Minnesota Hotel Deals

Med City Hotel & Suites
Med City Hotel & Suites
2.5 out of 5
4141 Maine Avenue SE, Rochester, MN, 55904
  • 10 min drive from Mayo Clinic
The price is $65 per night from Dec 17 to Dec 18
$65
per night
Dec 17 - Dec 18
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the clean rooms in our reviews. ...
4.3/5 Excellent! (999 reviews)
"Let us check in early."

Reviewed on Oct 28, 2022

Med City Hotel & Suites
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN, 55901
  • 2 min walk from Mayo Clinic
The price is $104 per night from Dec 2 to Dec 3
$104
per night
Dec 2 - Dec 3
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the helpful staff and the ...
3.6/5 Good! (1,033 reviews)
"This is one of many excellent places to stay near Mayo. But this recently renovated Kahler is not only right across the street from the hospital but staff is experienced with guests going there. Breakfast is at Caribou, not too relaxing as it’s a line and noisy, but more quiet seating can be found ..."

Reviewed on Nov 30, 2022

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
110 Civic Center Drive NW, Rochester, MN, 55901
  • 7 min walk from Mayo Clinic
The price is $121 per night from Dec 4 to Dec 5
$121
per night
Dec 4 - Dec 5
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Popular attractions Shops University Square ...
4.5/5 Wonderful! (256 reviews)
Rochester overnight
"Everything was great - pool area was very nice."

Reviewed on Nov 28, 2022

Hyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area
3.5 out of 5
220 S Broadway, Rochester, MN, 55904
  • 6 min walk from Mayo Clinic
The price is $93 per night from Dec 11 to Dec 12
$93
per night
Dec 11 - Dec 12
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast. Our guests praise the restaurant and the clean ...
4.3/5 Excellent! (256 reviews)
Mayo visit
"Nice hotel, didn’t see any info on paid parking. Should make that info available and clear. Great hospitable service"

Reviewed on Nov 23, 2022

Hotel Indigo Rochester – Mayo Clinic Area
Even Hotel Rochester - Mayo Clinic Area
Even Hotel Rochester - Mayo Clinic Area
3.5 out of 5
101 11TH AVENUE SW, SUITE A, Rochester, MN, 55902
  • 17 min walk from Mayo Clinic
The price is $89 per night from Dec 3 to Dec 4
$89
per night
Dec 3 - Dec 4
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a restaurant, and breakfast. Popular attractions Soldiers Field Veterans Memorial ...
4.7/5 Exceptional! (265 reviews)
"EVEN...should stand for EVERY VISITOR EVERY NEED! What a gorgeous hotel! What an accommodating hotel!!! beds and rooms were so comfy....yoga mats exercise balls and other equipment in the rooms!!! Wheel chairs available for patients coming from Mayo. Great place to relax and recover. STAFF IS AMAZING!!! ..."

Reviewed on Nov 20, 2022

Even Hotel Rochester - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN, 55904
  • 11 min drive from Mayo Clinic
The price is $70 per night from Dec 25 to Dec 26
$70
per night
Dec 25 - Dec 26
Stay at this 3-star family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
4.2/5 Very Good! (1,001 reviews)
"Great value hotel"

Reviewed on Nov 30, 2022

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
GuestHouse Inn & Suites Rochester
GuestHouse Inn & Suites Rochester
2.5 out of 5
435 16th Ave Nw, Rochester, MN, 55901
  • 26 min walk from Mayo Clinic
The price is $68 per night from Dec 2 to Dec 3
$68
per night
Dec 2 - Dec 3
Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms and the overall value in ...
4/5 Very Good! (1,000 reviews)
"Shuttle service was good and several places to eat were available"

Reviewed on Nov 24, 2022

GuestHouse Inn & Suites Rochester
Motel 6 Mankato, MN
Motel 6 Mankato, MN
2 out of 5
1731 Premier DR, Mankato, MN, 56001
  • 4 hours drive from Mayo Clinic
The price is $77 per night from Dec 4 to Dec 5
$77
per night
Dec 4 - Dec 5
Stay at this business-friendly motel in Mankato. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms ...
4.6/5 Wonderful! (592 reviews)
"Great value for the money, very basic but perfect for our needs."

Reviewed on Nov 26, 2022

Motel 6 Mankato, MN
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN, 55902
  • 2 min walk from Mayo Clinic
The price is $125 per night from Dec 22 to Dec 23
$125
per night
Dec 22 - Dec 23
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the restaurant and the helpful staff ...
3.7/5 Good! (1,002 reviews)
Good place and price
"Everything was great!! The staff and service was so nice and helpful! Only problem was the refrigerator not working."

Reviewed on Nov 29, 2022

Kahler Grand Hotel
AmericInn by Wyndham Mankato Event Center
AmericInn by Wyndham Mankato Event Center
2.5 out of 5
240 Stadium Road, Mankato, MN, 56001
  • 4 hours drive from Mayo Clinic
The price is $80 per night from Jan 1 to Jan 2
$80
per night
Jan 1 - Jan 2
Stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
4.4/5 Excellent! (1,001 reviews)
"Clean facility. Staff was very friendly!"

Reviewed on Nov 27, 2022

AmericInn by Wyndham Mankato Event Center
Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
3 out of 5
1900 Premier Drive, Mankato, MN, 56001
  • 4 hours drive from Mayo Clinic
The price is $100 per night from Dec 19 to Dec 20
$100
per night
Dec 19 - Dec 20
Stay at this 3-star business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
4/5 Very Good! (529 reviews)
Will stay here again
"This hotel was way nicer than another hotel I recently stayed at. This place was clean, people were extremely helpful, and a beautiful place to stay."

Reviewed on Nov 21, 2022

Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 out of 5
155 16th Avenue SW, Rochester, MN, 55902
  • 26 min walk from Mayo Clinic
The price is $98 per night from Dec 25 to Dec 26
$98
per night
Dec 25 - Dec 26
Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
4.3/5 Excellent! (467 reviews)
"Heater in first room did not work"

Reviewed on Nov 21, 2022

Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southern Minnesota

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Minnesota.

Choosing the right hotel in Minnesota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Minnesota’s 891 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southern Minnesota hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Minnesota. No matter your reason for visiting Southern Minnesota, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Minnesota hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Minnesota for as low as $65.

How many hotels are there in Southern Minnesota?

With over 891 hotels in Southern Minnesota, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Southern Minnesota?

Finding a cheap car rental deal in Southern Minnesota is as easy as scoring cheap hotels in Southern Minnesota. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southern Minnesota now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southern Minnesota right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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