Beginning of main content

Hotels Near Mayo Clinic

Hotels Near Mayo Clinic

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Last Minute Hot Rate® Hotel Deals in Mayo Clinic

We Hide Hotel Names So You Can Find 4-Star Hotels At 2-Star Prices. Choose the Location, Star Rating & Amenities. Let Hotwire Find You the Best Deal. Book Today!

Hotels near Mayo Clinic

Estimated price for 1 night/2 adults

Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5.00.1 km from Mayo Clinic
$119
Kahler Grand Hotel
Kahler Grand Hotel
3.0 out of 5.00.2 km from Mayo Clinic
$139
Marriott Rochester Mayo Clinic
Marriott Rochester Mayo Clinic
3.5 out of 5.00.2 km from Mayo Clinic
$159
DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area
DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area
3.5 out of 5.00.4 km from Mayo Clinic
$125
Brentwood Inn & Suites
Brentwood Inn & Suites
2.5 out of 5.00.3 km from Mayo Clinic
$95
Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN
3.0 out of 5.00.4 km from Mayo Clinic
$107
Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
3.5 out of 5.00.4 km from Mayo Clinic
$179
Hotel Indigo Rochester Downtown, an IHG Hotel
Hotel Indigo Rochester Downtown, an IHG Hotel
3.5 out of 5.00.4 km from Mayo Clinic
$103
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
0.5 km from Mayo Clinic
$118
Centerstone Plaza Hotel Soldiers Field/Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field/Mayo Clinic Area
3.0 out of 5.00.6 km from Mayo Clinic
$111
Aspen Select
Aspen Select
3.5 out of 5.01.7 km from Mayo Clinic
$108
GuestHouse Rochester
GuestHouse Rochester
2.5 out of 5.02.1 km from Mayo Clinic
$70
Map

Hotels Near Mayo Clinic

Starting to feel antsy? That just means it's time to hit the road. You've probably been dreaming of a trip to Downtown Rochester, and now is the perfect time to get a close-up view of Mayo Clinic. Hotwire has incredible rates on cheap hotels near Mayo Clinic that will keep you right where all the action is and leave you with some extra spending money. After all, you're going to want to make sure you do it right when you finally get away on your dream trip. Now let's get to planning!

More than a great location

Let others pay top dollar. Stop wasting time exploring other sites for the best price because we are pretty sure we have them right here. Hotwire also makes it a snap to discover cheap hotels in Mayo Clinic to save you time that you can devote to doing any of the things to do in the area. With the time you saved looking for a hotel room, you can spend your additional time exploring the best things to do in Downtown Rochester that sometimes fly under the radar. Take advantage of that extra time by getting a deeper understanding of the area by chatting with locals and finding some locals-only hotspots. And, with hotels near Downtown Rochester, you know you'll be smack dab in the center of the action.

Save more than just time

If you've been on the lookout for hotels near Mayo Clinic in Downtown Rochester that don't cost an arm and a leg, you're in the right place. We stick to a simple philosophy at Hotwire. With our Hotwire Hot Rate, we won't show you the hotels' names, but we'll show you the great rate and all the amenities you'll be getting when you stay. It's no mystery that we make our site hackable. We want you to have more cash back in your pocket, so you have extra cash to explore. More funds mean you can make the most of Mayo Clinic. By all means, save as much as you can on cheap hotels near Mayo Clinic. We dare you. Sort accommodations by:

  • Hotwire Hot Rate: A wonderful hotel near Mayo Clinic for an absurdly affordable price? It's a no-brainer.
  • Price: Have a rate in mind? We bet no matter how low it is, we have a place that fits your budget.
  • Amenities: Want complimentary Wi-Fi? Perhaps a room with an amazing view? You know, the amenities that bring your vacation up another level.
  • Reviews: Peruse through the reviews and find out what other travelers adored about Mayo Clinic.

Call up your best friends, load up your suitcase, and prepare for adventure! We have heaps of hotels near Mayo Clinic ready and waiting for you to paint Downtown Rochester red. Well, about 269 hotels, but who's counting? Make 2021 one for the books by solidifying your trip today. Reserve your spot now before it's booked.