Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion

Hotels near Mayo Clinic Florida

Estimated price for 1 night/2 adults


Mayo Clinic Florida Hotel Guide

Search for hotels near Mayo Clinic Florida on Hotwire. You can easily find your hotels near Mayo Clinic Florida using one of the methods below:

  • View our selection of featured hotels near Mayo Clinic Florida
  • Use the map to find hotels in the neighborhood you prefer
  • Use the filters to see hotels in a specific area near Mayo Clinic Florida, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) near Mayo Clinic Florida
  • Enter your travel dates to view the best deals on hotels in Mayo Clinic Florida - while they last