Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Featured Downtown St. Louis Casinos

Estimated price for 1 night/2 adults

Map

Recently Booked Downtown St. Louis Casino Hotels

Hotels in Downtown St. Louis

St. Louis is a city that has a lot going on, but you have your sights set on Downtown St. Louis. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Downtown St. Louis has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Downtown St. Louis hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Downtown St. Louis underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Downtown St. Louis city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Downtown St. Louis cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Downtown St. Louis at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Downtown St. Louis hotel you want, book it, and never look back. Because your great escape is ahead of you.