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Hotels in Southeast Missouri

See all 233 Properties in Southeast Missouri
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N, Poplar Bluff
    2.0 out of 5.0
     
     

    Situated in Poplar Bluff, this hotel is within 9 mi (15 km) of Margaret Harwell Art Museum, Mo-Ark Regional Railroad Museum, and Ozark Ridge Golf Course. The ...

    Motel 6 Poplar Bluff, MO$58

    Motel 6 Poplar Bluff, MO$58
    Super 8 by Wyndham Pevely

    Super 8 by Wyndham Pevely

    1711 Highway Z, Pevely
      2.0 out of 5.0
       
       

      Situated in Pevely, this motel is within 25 mi (40 km) of Suson Park, Grants Farm, and Missouri Civil War Museum. LIFECHURCH and Laumeier Sculpture Park are ...

      Super 8 by Wyndham Pevely$51

      Super 8 by Wyndham Pevely$51
      Pear Tree Inn Cape Girardeau Near the Medical Center

      Pear Tree Inn Cape Girardeau Near the Medical Center

      3248 William St, Cape Girardeau
        2.5 out of 5.0
         
         

        Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

        Pear Tree Inn Cape Girardeau Near the Medical Center$70

        Pear Tree Inn Cape Girardeau Near the Medical Center$70
        Americas Best Value Inn & Suites Sikeston

        Americas Best Value Inn & Suites Sikeston

        220 S Interstate Dr, Miner
          2.0 out of 5.0
           
           

          Situated in a rural location, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic ...

          Americas Best Value Inn & Suites Sikeston$60

          Americas Best Value Inn & Suites Sikeston$60
          Best Western Plus Sikeston

          Best Western Plus Sikeston

          120 S Interstate Drive, Miner
            2.5 out of 5.0
             
             

            Situated in Miner, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic Site and Kentucky ...

            Best Western Plus Sikeston$85

            Best Western Plus Sikeston$85
            Quality Inn

            Quality Inn

            1400 W Liberty St, Farmington
              2.5 out of 5.0
               
               

              Located in the heart of Farmington, this hotel is within 9 mi (15 km) of Crown Pointe Golf Club, Columbia Park, and Missouri Mines State Historic Site. Bonne ...

              Quality Inn$55

              Quality Inn$55
              Comfort Inn Festus

              Comfort Inn Festus

              1303 Veterans Blvd, Festus
                2.5 out of 5.0
                 
                 

                Situated in Festus, this hotel is within 20 mi (32 km) of Mastodon State Historic Site, Sunridge Park, and Persimmon Ridge Winery. Suson Park and Swing-A-Round ...

                Comfort Inn Festus$83

                Comfort Inn Festus$83
                Drury Plaza Hotel Cape Girardeau Conference Center

                Drury Plaza Hotel Cape Girardeau Conference Center

                3351 Percy Drive, Cape Girardeau
                  3.0 out of 5.0
                   
                   

                  Situated in Cape Girardeau, this hotel is 2.2 mi (3.5 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

                  Drury Plaza Hotel Cape Girardeau Conference Center$125

                  Drury Plaza Hotel Cape Girardeau Conference Center$125
                  Pear Tree Inn Cape Girardeau West

                  Pear Tree Inn Cape Girardeau West

                  103 Cape West Pkwy, Cape Girardeau
                    2.5 out of 5.0
                     
                     

                    Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

                    Pear Tree Inn Cape Girardeau West$70

                    Pear Tree Inn Cape Girardeau West$70
                    Drury Inn Poplar Bluff

                    Drury Inn Poplar Bluff

                    2220 N Westwood Blvd, Poplar Bluff
                      3.0 out of 5.0
                       
                       

                      Located in the heart of Poplar Bluff, this hotel is 2.5 mi (4 km) from Margaret Harwell Art Museum and 2.7 mi (4.3 km) from Mo-Ark Regional Railroad Museum. ...

                      Drury Inn Poplar Bluff$115

                      Drury Inn Poplar Bluff$115
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                      Southeast Missouri Hotel Guide

                      Search for hotels in Southeast Missouri on Hotwire. Finding hotels in Southeast Missouri using one of the methods below, is simple and quick:

                      • Look through our selection of featured hotels in Southeast Missouri and check into the different facilities they offer
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