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Hotels in Poplar Bluff

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Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
  • 24 min walk from Poplar Bluff Regional Medical Center
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,001 reviews)
Staff was amazing and super nice. Room was very clean.

Reviewed on Dec 11, 2025

Motel 6 Poplar Bluff, MO
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 out of 5
3109 Oak Grove Poplar Bluff MO
  • 3 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (856 reviews)
The rooms were very clean and well maintained and th e staff was great and the young lady who checked us in was awsome at her job she helped me get the smart tv workin and has a very professional and respectfull through the hole stay we thank this is the nicest hotel i ve stayed at by far andcwill ...

Reviewed on Dec 23, 2025

Fairfield Inn & Suites by Marriott Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
  • 10 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.6/10 Excellent! (706 reviews)
The front desk woman was great

Reviewed on Dec 21, 2025

Holiday Inn Poplar Bluff by IHG
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
  • 18 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (968 reviews)
The breakfast was excellent. The food was hot and tastey! There are excellent choices!

Reviewed on Dec 21, 2025

Drury Inn & Suites Poplar Bluff
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
  • 13 min walk from Poplar Bluff Regional Medical Center
Stay at this hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (796 reviews)
Every single time I come to this location, it always exceeds my expectations. It's always clean.They always have hot coffee and they are super friendly!! Never have anything bad to say about them

Reviewed on Dec 3, 2025

Hampton Inn Poplar Bluff
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
  • 10 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly motel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Popular attractions North Main Street Historic ...
6.4/10 (623 reviews)
In my single room no place to hang clothes

Reviewed on Dec 5, 2025

Super 8 by Wyndham Poplar Bluff Missouri
Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge

2.5 out of 5
399 Hwy T Poplar Bluff MO
  • 7 min drive from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (212 reviews)
A work buddy, and I stayed for 3 nights. Accommodation was very good and we will stay again. When in the area.

Reviewed on Mar 14, 2025

Bullwinkles Rustic Lodge
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 out of 5
2582 N Westwood Blvd Poplar Bluff MO
  • 16 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (399 reviews)
it was a nice stay, room was a little warm, thermostat may need changing out. Other than that it was great.

Reviewed on Dec 16, 2025

Comfort Inn Poplar Bluff North
Waterfront Home Near Mark Twain National Forest

Waterfront Home Near Mark Twain National Forest

3.5 out of 5
Poplar Bluff MO
  • 4 min drive from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly apartment in Poplar Bluff. Enjoy free parking and air conditioning. Popular attractions Ozark Ridge Golf Course and North ...
Waterfront Home Near Mark Twain National Forest
40-acre Poplar Bluff Nature Lovers Paradise!

40-acre Poplar Bluff Nature Lovers Paradise!

3 out of 5
Poplar Bluff MO
  • 8 min drive from Poplar Bluff Regional Medical Center
Stay at this cottage in Poplar Bluff. Enjoy free parking, patios, and in-room fireplaces.
10/10 Exceptional! (3 reviews)
Beautiful place enjoyed our stay

Reviewed on Apr 4, 2025

40-acre Poplar Bluff Nature Lovers Paradise!
Dexter Inn

Dexter Inn

2.5 out of 5
1807 W Business US Highway 60 Dexter MO
  • 47 min drive from Poplar Bluff Regional Medical Center
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
6.8/10 (332 reviews)
Great for a small town mom and pop hotel. I’ll probably come here a lot more

Reviewed on Nov 1, 2025

Dexter Inn
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
  • 46 min drive from Poplar Bluff Regional Medical Center
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
10/10 Exceptional! (3 reviews)
Staff was helpful and professional. The rooms were clean and comfortable

Reviewed on Nov 16, 2025

Hampton Inn By Hilton Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Poplar Bluff

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How many hotels are there in Poplar Bluff?

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