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Hotels in Mayfield Heights

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Comfort Inn Mayfield Heights Cleveland East

Comfort Inn Mayfield Heights Cleveland East

2.5 out of 5
1421 Golden Gate Blvd Mayfield Heights OH
  • 16 min walk from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Mayfield Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,000 reviews)
The stay was good but people in room above in the early morning hours were doing skit of moving around like they we’re remodeling the room and it happened both nights of our stay.

Reviewed on Mar 26, 2026

Comfort Inn Mayfield Heights Cleveland East
Staybridge Suites Cleveland Mayfield Heights Beachwood by IHG

Staybridge Suites Cleveland Mayfield Heights Beachwood by IHG

3 out of 5
6103 Landerhaven Drive Mayfield Heights OH
  • 4 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Mayfield Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,002 reviews)
Everything was great

Reviewed on Apr 1, 2026

Staybridge Suites Cleveland Mayfield Heights Beachwood by IHG
Hotel Indigo Cleveland Downtown by IHG

Hotel Indigo Cleveland Downtown by IHG

3.5 out of 5
651 Huron Rd E Cleveland OH
  • 33 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,615 reviews)
Hotel was great, clean, nice, friendly staff

Reviewed on Apr 1, 2026

Hotel Indigo Cleveland Downtown by IHG
The Westin Cleveland Downtown

The Westin Cleveland Downtown

4 out of 5
777 Saint Clair Ave Ne Cleveland OH
  • 34 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,109 reviews)
The room was very nice and the staff was wonderful

Reviewed on Apr 4, 2026

The Westin Cleveland Downtown
Hotel Cleveland, Autograph Collection

Hotel Cleveland, Autograph Collection

4 out of 5
24 Public Sq Cleveland OH
  • 34 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this historic hotel in Cleveland. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the helpful ...
9/10 Wonderful! (298 reviews)
Outstanding in every way! Staff was exceptional; front desk, valets and restaurant servers were all among the best I've ever met. Hotel and rooms were clean, modern and luxurious-they put a lot of money into refurbishing the place and it shows. We had breakfast at Mowery's- great selection and fantastic ...

Reviewed on Apr 3, 2026

Hotel Cleveland, Autograph Collection
Holiday Inn Cleveland Clinic by IHG

Holiday Inn Cleveland Clinic by IHG

3 out of 5
8650 Euclid Ave Cleveland OH
  • 25 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,309 reviews)
Clean room . Great staff.

Reviewed on Apr 2, 2026

Holiday Inn Cleveland Clinic by IHG
Kimpton Schofield Hotel by IHG

Kimpton Schofield Hotel by IHG

4.5 out of 5
2000 East Ninth Street Cleveland OH
  • 33 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this luxury hotel in Cleveland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant and ...
8.8/10 Excellent! (1,005 reviews)
Bar/restaurant was amazing, our server was great and the korean chicken sandwich was out of this world good!!!

Reviewed on Apr 4, 2026

Kimpton Schofield Hotel by IHG
Hyatt Regency Cleveland At The Arcade

Hyatt Regency Cleveland At The Arcade

4 out of 5
420 Superior Ave E Cleveland OH
  • 34 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,142 reviews)
Highly recommend

Reviewed on Apr 2, 2026

Hyatt Regency Cleveland At The Arcade
Drury Plaza Hotel Cleveland Downtown

Drury Plaza Hotel Cleveland Downtown

3 out of 5
1380 East 6th Street Cleveland OH
  • 34 min drive from Cleveland Clinic - Hillcrest Hospital
Stay at this hotel in Cleveland. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (2,701 reviews)
Absolutely incredible hotel! Best for families. Food was awesome

Reviewed on Apr 4, 2026

Drury Plaza Hotel Cleveland Downtown
Spark by Hilton Cleveland Beachwood

Spark by Hilton Cleveland Beachwood

3 out of 5
26300 Chagrin Blvd Beachwood OH
  • 12 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Beachwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (294 reviews)
Weed smell all night checked out couldn’t breathe left early didn’t get refund

Reviewed on Apr 3, 2026

Spark by Hilton Cleveland Beachwood
Wyndham Independence

Wyndham Independence

4 out of 5
6200 Quarry Lane Independence OH
  • 36 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Independence. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Cleveland Metroparks ...
6.4/10 (1,077 reviews)
Horrible parking lot lighting, hot tub not working, no water for hours due to repairs, exterior littered with debris & trash. Ok for the price for a night but if your looking for comfortable,relaxing nights this is not the place

Reviewed on Apr 4, 2026

Wyndham Independence
La Quinta Inn & Suites by Wyndham Cleveland - Airport North

La Quinta Inn & Suites by Wyndham Cleveland - Airport North

3 out of 5
4222 W 150th St Cleveland OH
  • 51 min drive from Cleveland Clinic - Hillcrest Hospital
Book a stay at this business-friendly hotel in Cleveland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,972 reviews)
“Free parking” is only free for 1 night. Shuttle stops running at 12am

Reviewed on Apr 3, 2026

La Quinta Inn & Suites by Wyndham Cleveland - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mayfield Heights

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $66. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mayfield Heights hotel deals at the last minute.

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Frequently Asked Questions About Mayfield Heights hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Mayfield Heights?

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