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Featured Florence Family Hotels

Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...

Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr, Florence, SC
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Fairfield Inn by Marriott Hartsville
200 S 4th St, Hartsville, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Days Inn by Wyndham Dillon
823 Radford Blvd, Dillon, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...

The Landmark Inn
1301 South 4th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Florence

Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
I made a reservation in February for Labor Day weekend reserved 3 rooms of 2 beds and pull out sofa bed. Was told that only 2 of those rooms exist at this location. Then said Nevermind we do have that. They planned on putting a mattress on the floor of a king room that they were in the process of ...
Reviewed on Sep 4, 2024

Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (12 reviews)
Everything was wonderful. My only suggestion is to put an area rug where the sofa and table are located. With no carpet in the room it echos to much.
Reviewed on Sep 5, 2025

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2101 Florence Harllee Blvd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,014 reviews)
Vaca stay for 2
Internet was perfect, room clean. Staff excellent!
Reviewed on Oct 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Florence

Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...

Comfort Suites Florence I-95
2120 West Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Beach Hotels in Florence
- Hotels with an Indoor Pool in Florence
- Luxury Hotels in Florence
- Hotels with Hot Tubs in Florence
- Resorts & Hotels with Spas in Florence
- Apartment Hotel in Florence
- Hotels with smoking rooms in Florence
Other Accommodation Types
Top Points of Interests in Florence
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence Museum
- Hotels near Florence National Cemetery
- Hotels near Florence Veterans Park
- Hotels near The Traces Golf Club
- Hotels near Oakdale Country Club
- Hotels near Columns Plantation
Cities near Florence
- Hartsville Hotels (21.27 mi)
- Dillon Hotels (27.21 mi)
- Cheraw Hotels (35.17 mi)
- Southeastern United States Hotels (264.9 mi)
- Lake City Hotels (22.42 mi)
- Latta Hotels (21.48 mi)
- Darlington Hotels (9.59 mi)
- Marion Hotels (21.04 mi)
- The Carolinas Hotels (50.37 mi)
- Bennettsville Hotels (29.4 mi)
- Hemingway Hotels (35.7 mi)
- Hamer Hotels (31.63 mi)
- Bishopville Hotels (27.46 mi)
- Mullins Hotels (29.34 mi)
- Aynor Hotels (35.18 mi)
- Timmonsville Hotels (10.89 mi)
- The South Hotels (584.78 mi)
- Lynchburg Hotels (19.91 mi)
- Sellers Hotels (17.89 mi)
- Galivants Ferry Hotels (31.37 mi)
