Search Cheap Flights toFlorence
Search 400 airlines and 321,000 hotels worldwide.
Stop Planning & Start Exploring
FREE 24 hour cancellation on most flights
Florence Flights as Low as $370
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Tue, Oct 7 - Sat, Oct 11
PHL
Philadelphia Intl.
FLO
Florence Regional
$403 Roundtrip, just found
$403
Roundtrip
just found
Tue, Oct 7 - Sat, Oct 11
PHL
Philadelphia Intl.
FLO
Florence Regional
$414 Roundtrip, found 3 days ago
$414
Roundtrip
found 3 days ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$433 Roundtrip, found 1 day ago
$433
Roundtrip
found 1 day ago
Wed, Jul 16 - Sun, Jul 20
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$437 Roundtrip, found 3 days ago
$437
Roundtrip
found 3 days ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$441 Roundtrip, found 1 day ago
$441
Roundtrip
found 1 day ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$442 Roundtrip, found 1 day ago
$442
Roundtrip
found 1 day ago
Tue, Oct 7 - Sat, Oct 11
PHL
Philadelphia Intl.
FLO
Florence Regional
$459 Roundtrip, just found
$459
Roundtrip
just found
Wed, Oct 8 - Mon, Oct 13
PHL
Philadelphia Intl.
FLO
Florence Regional
$469 Roundtrip, found 1 day ago
$469
Roundtrip
found 1 day ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$488 Roundtrip, found 3 days ago
$488
Roundtrip
found 3 days ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$496 Roundtrip, found 1 day ago
$496
Roundtrip
found 1 day ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$504 Roundtrip, found 1 day ago
$504
Roundtrip
found 1 day ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$505 Roundtrip, found 1 day ago
$505
Roundtrip
found 1 day ago
Tue, Oct 7 - Sat, Oct 11
PHL
Philadelphia Intl.
FLO
Florence Regional
$506 Roundtrip, just found
$506
Roundtrip
just found
Wed, Jul 16 - Sun, Jul 20
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$509 Roundtrip, found 3 days ago
$509
Roundtrip
found 3 days ago
Wed, Jul 16 - Sat, Jul 19
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$544 Roundtrip, found 1 day ago
$544
Roundtrip
found 1 day ago
Cheap Flights to Florence
Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Florence
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the DLL airport.
What is the cheapest month to fly to Florence?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in July, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Florence?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.
What airport is best to fly into Florence?
When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.
How much are flights to Florence?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $370, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Florence?
The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $370 right now, why wait?
Destination airport | Florence Regional |
Destination airport IATA code | FLO |
Roundtrip price | $370 |
Last Minute Hotel Deals in Florence
Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,268 reviews)
"Better than expected, great location, just needs minor repairs from renovation i.e. old headboard mounting holes. Free WiFi."
Reviewed on Jul 5, 2025
Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,014 reviews)
Great travel overnight choice
"Friendly and efficient staff. Clean and comfortable facility. Convenient location for travel and dining."
Reviewed on Jul 2, 2025
Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,075 reviews)
"Super clean, nice hotel. Newer building, easy stay."
Reviewed on Jul 4, 2025
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,225 reviews)
"Clean, simple, newer hotel in the area. Very happy with stay."
Reviewed on Jul 4, 2025
Hyatt Place Florence Downtown
100 East Evans Street Florence, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,005 reviews)
"Nice and friendly faces 👌"
Reviewed on Jul 5, 2025
La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,648 reviews)
"Nicely updated. Bathroom has some mold around tub. Very quiet. Very helpful and friendly staff. Easy access from an to 95."
Reviewed on Jul 3, 2025
TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.8/10 Excellent! (603 reviews)
"The front desk was wonderful! The breakfast was good!"
Reviewed on Jun 30, 2025
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,004 reviews)
A traveler‘s base camp
"Here is a great location for a traveler. I set up my base camp here and I am spending five nights over the Fourth of July weekend. Everywhere I’m looking to go is nearby. Even Savannah, Georgia is about an hour and a half away."
Reviewed on Jul 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Nearby Cities
Popular Flights to Florence
Popular Flight Routes
- Atlanta to New York
- Detroit to Las Vegas
- Dallas to Atlanta
- Dallas to Yosemite National Park
- Toronto to Edmonton
- Chicago to Tulum
- Houston to Lake Tahoe
- Chicago to Las Vegas
- Dallas to Miami
- Dallas to Lake Tahoe
- New York to Miami
- New York to Las Vegas
- Miami to Atlanta
- Minneapolis St Paul to Fort Walton Beach Destin
- Dallas to Branson
- Cleveland to Vero Beach
- Managua to Miami
- Atlanta to Boston
- Austin to Tulum
- Calgary to Vancouver
Flights to Our Favorite Destinations
- Flights to Las Vegas
- Flights to New York
- Flights to Orlando
- Flights to Myrtle Beach
- Flights to Chicago
- Flights to San Diego
- Flights to Panama City Beach
- Flights to Destin
- Flights to Los Angeles
- Flights to Miami
- Flights to Gulf Shores
- Flights to Ocean City
- Flights to Boston
- Flights to Nashville
- Flights to San Francisco
- Flights to Pigeon Forge
Top Florence Hotels
- Howard Johnson by Wyndham Florence
- Quality Inn & Suites Florence Civic Center
- Hyatt Place Florence Downtown
- La Quinta Inn & Suites by Wyndham Florence
- TownePlace Suites by Marriott Florence
- Days Inn by Wyndham Florence/I-95 North
- Microtel Inn & Suites by Wyndham Florence
- Days Inn by Wyndham Florence Near Civic Center
- Staybridge Suites Florence - Civic Center by IHG
- Tru by Hilton Florence I-95
- Country Inn & Suites by Radisson, Florence, SC
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Comfort Suites Florence I-95