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Downtown San Francisco Vacations

Pack those stellar shades. We have Downtown San Francisco vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Downtown San Francisco – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Downtown San Francisco vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Downtown San Francisco

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Downtown San Francisco vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Downtown San Francisco well.

Downtown San Francisco Flight + Hotel packages

Top Hotel Deals

See all 178 Hotels in Downtown San Francisco
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
    4.0 out of 5.0
     
     

    The Asian-inspired Hotel Nikko San Francisco is located downtown, a 4-minute walk from Union Square and the designer shops of Westfield San Francisco Centre. ...

    Hotel Nikko San Francisco$166

    Hotel Nikko San Francisco$166
    The Westin St. Francis San Francisco on Union Square

    The Westin St. Francis San Francisco on Union Square

    335 Powell Street, San Francisco
      4.0 out of 5.0
       
       

      This elegant and historic 1904 hotel offers a prime location across from San Francisco's Union Square; cable cars stop right at the front door, and the Financial ...

      The Westin St. Francis San Francisco on Union Square$134

      The Westin St. Francis San Francisco on Union Square$134
      San Francisco Marriott Marquis

      San Francisco Marriott Marquis

      780 Mission Street, San Francisco
        4.0 out of 5.0
         
         

        The San Francisco Marriott Marquis is steps from Union Square shopping, Chinatown, cable cars, and the San Francisco Museum of Modern Art.

        San Francisco Marriott Marquis$169

        San Francisco Marriott Marquis$169
        Villa Florence San Francisco on Union Square

        Villa Florence San Francisco on Union Square

        225 Powell St, San Francisco
          4.0 out of 5.0
           
           

          Infused with the spirit of Italy, this romantic downtown San Francisco retreat is on the Powell Street cable car line, less than a block from Union Square; theaters ...

          Villa Florence San Francisco on Union Square$135

          Villa Florence San Francisco on Union Square$135
          Stanford Court San Francisco

          Stanford Court San Francisco

          905 California Street, San Francisco
            4.0 out of 5.0
             
             

            Nob Hill area

            Stanford Court San Francisco$139

            Stanford Court San Francisco$139
            The Park Central San Francisco

            The Park Central San Francisco

            50 3rd St, San Francisco
              4.0 out of 5.0
               
               

              Located in the heart of the South of Market district (SoMa), The Park Central San Francisco is across from Yerba Buena Gardens and close to the San Francisco ...

              The Park Central San Francisco$113

              The Park Central San Francisco$113
              Sweden House Hotel

              Sweden House Hotel

              570 O'farrell St, San Francisco
                2.5 out of 5.0
                 
                 

                Located in Downtown San Francisco, this hotel is within a 10-minute walk of Westfield San Francisco Centre and Asian Art Museum of San Francisco. San Francisco ...

                Sweden House Hotel$40

                Sweden House Hotel$40
                Hotel Spero

                Hotel Spero

                405 Taylor St, San Francisco
                  4.0 out of 5.0
                   
                   

                  Hotel Spero is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks from the Powell Street cable car.

                  Hotel Spero$129

                  Hotel Spero$129
                  Omni San Francisco Hotel

                  Omni San Francisco Hotel

                  500 California St, San Francisco
                    4.5 out of 5.0
                     
                     

                    Located at the base of Nob Hill, Omni San Francisco Hotel is a 13-minute walk from Union Square. The Embarcadero Center, BART Station, and North Beach are within ...

                    Omni San Francisco Hotel$184

                    Omni San Francisco Hotel$184
                    Parc 55 San Francisco - A Hilton Hotel

                    Parc 55 San Francisco - A Hilton Hotel

                    55 Cyril Magnin St, San Francisco
                      4.0 out of 5.0
                       
                       

                      Just off Market Street, downtown San Francisco's major thoroughfare, this contemporary 32-story hotel is 1 block from San Francisco Centre shops and 3 blocks ...

                      Parc 55 San Francisco - A Hilton Hotel$161

                      Parc 55 San Francisco - A Hilton Hotel$161

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.