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Choose from 876 Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 35 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,205 reviews)
Clean room

Reviewed on Apr 17, 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
  • 38 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,214 reviews)
The breakfast was good, the pool and hot tub were dirty looking, the water looked murky and there was stuff floating in it. We were disappointed because that's one of the reasons we booked there. The bathroom was small looked like a bathroom in a small apartment. The staff was nice, but I don't think ...

Reviewed on Apr 16, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
  • 20 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
9.2/10 Wonderful! (1,626 reviews)
Very clean room and great staff

Reviewed on Apr 16, 2026

The Wildwood Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 36 min drive from Chandler Hill Vineyards
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
Staff was super rude as a frequent traveler we abide by all rules and signs posted when there is no rules or signs posted you treat your guest like trash for not knowing the rules that you never explained in any way.. worst vacation EVER . STAY ANYWHERE ELSE BUT HERE!

Reviewed on Apr 11, 2026

Ameristar Casino Resort and Spa
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr Maryland Heights MO
  • 36 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,001 reviews)
The room was nice and clean, the staff were very friendly and helpful. the only thing I wish is they had better breakfast options.

Reviewed on Apr 13, 2026

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

3 out of 5
355 Chesterfield Ctr Chesterfield MO
  • 24 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,144 reviews)
The staff was very friendly and welcoming. The room was clean and the bed was comfortable. You can't beat the free 5:30 kickback! The food and drinks were great! We would definitely stay at this location again the next time we are in St. Louis.

Reviewed on Apr 17, 2026

Drury Plaza Hotel St. Louis Chesterfield
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
11228 Lone Eagle Dr Bridgeton MO
  • 41 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Bridgeton. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,000 reviews)
Ceiling pouring in water, bar staff was rude and dismissive, expedia sent the wrong reservation date and had to pay again upon arrival. Frustrating experience overall.

Reviewed on Apr 14, 2026

Crowne Plaza St. Louis Airport by IHG
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

3 out of 5
5 Lambert Drury Place (I-44 & 141) Valley Park MO
  • 36 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Valley Park. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,017 reviews)
Excellent

Reviewed on Apr 16, 2026

Drury Inn & Suites Southwest St. Louis
Best Western Plus Fenton

Best Western Plus Fenton

2.5 out of 5
1680 Fenton Business Park Ct Fenton MO
  • 41 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (265 reviews)
Clean room and comfortable bed and that is all we could ask for passing through town.

Reviewed on Apr 16, 2026

Best Western Plus Fenton
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St St. Charles MO
  • 36 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
It was a good experience

Reviewed on Apr 15, 2026

Comfort Suites St Charles - St Louis
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

2.5 out of 5
12220 Dorsett Rd Maryland Heights MO
  • 36 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and ...
8/10 Very Good! (1,062 reviews)
Nice place comfortable and close to hospital and Dr appts

Reviewed on Apr 14, 2026

Best Western Plus St. Louis West-Westport
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

3 out of 5
11980 Olive Blvd St. Louis MO
  • 35 min drive from Chandler Hill Vineyards
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
The hotel is clean and updated. There is a parking deck, which protects your vehicle from inclement weather. Breakfast is great, and they also have a light dinner with nice buffet options. All staff are friendly and helpful. Highly recommend this hotel.

Reviewed on Apr 17, 2026

Drury Plaza Hotel St. Louis Creve Coeur
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Defiance

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How many hotels are there in Defiance?

With over 876 hotels in Defiance, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $102.

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