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Defiance Vacations

Pack those stellar shades. We have Defiance vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Defiance – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Defiance vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Defiance

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Defiance vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Defiance well.

Top Hotel Deals

See all 141 Hotels in Defiance
Hawthorn Suites by Wyndham St. Louis Westport Plaza

Hawthorn Suites by Wyndham St. Louis Westport Plaza

1881 Craigshire Rd, Maryland Heights
3.5 out of 5.0

Situated in the business district, this hotel is within 9 mi (15 km) of St. Louis Car Museum, Hollywood Casino Amphitheatre, and Sophia M. Sachs Butterfly House. ...

$81

$81
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights
4.0 out of 5.0

Situated near the airport, this hotel is 1.4 mi (2.3 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Lindenwood University and Family Arena. ...

$69

$69
La Quinta Inn & Suites St. Louis Airport - Riverport

La Quinta Inn & Suites St. Louis Airport - Riverport

13615 Riverport Drive, Maryland Heights
3.5 out of 5.0

Situated near the airport, this hotel is 0.5 mi (0.9 km) from Hollywood Casino Amphitheatre and within 6 mi (10 km) of Historic Aircraft Restoration Museum and ...

$76

$76
Days Inn St. Louis Westport MO

Days Inn St. Louis Westport MO

1970 Craig Rd, Maryland Heights

Near I-270, this suburban St Louis hotel is a half-mile from West Port Plaza, 4 miles from UMB Bank Pavilion, and 6 miles from Lambert-St Louis International ...

$64

$64
Motel 6 Hazelwood

Motel 6 Hazelwood

5781 Campus Ct, Hazelwood
2.5 out of 5.0

Situated near the airport, this motel is within 6 mi (10 km) of St. Louis Mills Mall, James S. McDonnell Prologue Room, and Par-Tee Recreation Center. Payne-Gentry ...

$36

$36
The Wildwood Hotel

The Wildwood Hotel

2801 Fountain Pl, Wildwood
4.0 out of 5.0

Situated in Grover, this hotel is within 9 mi (15 km) of Dr. Edmund A. Babler Memorial State Park, Hidden Valley Ski Resort, and Babler State Park. Westfield ...

$90

$90
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

333 Chesterfield Center East, Chesterfield
3.0 out of 5.0

Situated in the business district, this hotel is within 2 mi (3 km) of Westfield Chesterfield Mall, Sophia M. Sachs Butterfly House, and Faust Park. Taubman ...

$108

$108
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

355 Chesterfield Ctr, Chesterfield
3.5 out of 5.0

Located in the heart of Chesterfield, this hotel is within 2 mi (3 km) of Westfield Chesterfield Mall, Sophia M. Sachs Butterfly House, and Faust Park. Taubman ...

$110

$110
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

15431 Conway Rd, Chesterfield
3.0 out of 5.0

Situated in the suburbs, this aparthotel is within 2 mi (3 km) of Sophia M. Sachs Butterfly House, Westfield Chesterfield Mall, and Faust Park. Myseum and Taubman ...

$99

$99
Country Inn & Suites by Radisson, St. Charles, MO

Country Inn & Suites by Radisson, St. Charles, MO

1190 S Main St, St. Charles
2.5 out of 5.0

Located in St. Charles Historic District, this hotel is within a 15-minute walk of Lewis & Clark Boathouse and Nature Center and First Missouri State Capitol ...

$84

$84

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.