Search for Cheap Deals on
Hotels in St. Ann

Choose from 1906 St. Ann Hotel Deals

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
  • 24 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,869 reviews)
Ice cold rooms! Loved it! Staff was friendly and helpful!

Reviewed on Mar 9, 2026

Pear Tree Inn St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
  • 24 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,542 reviews)
Friendly helpful staff They allso have an airport shuttle 24/7!

Reviewed on Mar 9, 2026

Wingate by Wyndham St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 13 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,123 reviews)
The water pressure in our room's shower was the worst I've ever experienced.

Reviewed on Mar 9, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 5 min walk from St. Louis Union Station
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,647 reviews)
So fun and eclectic! !

Reviewed on Mar 10, 2026

21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 16 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,360 reviews)
National park near, friendlty & welcoming staff, great accommodations, wonderful food & cheers, all star view from 8th floor balcony

Reviewed on Mar 9, 2026

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 17 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,011 reviews)
We had a great experience! The hotel was beautiful, the staff were friendly and helpful and we got an upgraded room that made all the difference - a bigger bathroom for 3 girls! The location was ideal, right by the Arch and the view was spectacular. I also want to call out the staff that did the ...

Reviewed on Mar 9, 2026

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 32 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,217 reviews)
The room was very clean, staff were friendly, casino was a lot of fun!!! Great place to stay for the weekend or if you are passing through!

Reviewed on Feb 22, 2026

Hollywood Casino & Hotel St. Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
  • 18 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,498 reviews)
The staff were very friendly and efficient. Check in was a breeze.

Reviewed on Mar 8, 2026

River City Casino & Hotel
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
  • 3 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,347 reviews)
Rooms are very small and poorly decorated but clean. (Currently property is under renovation, so decor should be updated soon). Pool and hot tub areas clean but definitely showing their age! (Just look old and water feature on the wall has hard water buildup making it look dirty and again old). The ...

Reviewed on Mar 7, 2026

Drury Inn & Suites St. Louis Union Station
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
  • 13 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,130 reviews)
Room was excellent clean no issues

Reviewed on Mar 7, 2026

Live by Loews - St.Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
  • 31 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,125 reviews)
Nice rooms. They were clean but had a musty smell. Right next to Cracker Barrel which was nice!!

Reviewed on Mar 9, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
  • 8 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
8/10 Very Good! (698 reviews)
The room was mostly satisfactory, and the buffet breakfast was good, although not varied enough day to day, but the neighborhood was questionable. The hotel has an armed security guard, and I was cautioned about venturing out at night.

Reviewed on Mar 10, 2026

Home2 Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in St. Ann

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your St. Ann hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in St. Ann.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of St. Ann’s 1,906 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $103. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great St. Ann hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in St. Ann. No matter your reason for visiting St. Ann, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About St. Ann hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in St. Ann for as low as $103.

How many hotels are there in St. Ann?

With over 1,906 hotels in St. Ann, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $103.

How to find cheap car rentals in St. Ann?

Finding a cheap car rental deal in St. Ann is as easy as scoring cheap hotels in St. Ann. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.