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Hotels in Perryville

Choose from 161 Perryville Hotel Deals

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (542 reviews)
Clean room

Reviewed on Dec 21, 2025

Holiday Inn Express & Suites Perryville by IHG
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (941 reviews)
Clean and comfortable room

Reviewed on Dec 18, 2025

Super 8 by Wyndham Perryville
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
  • 27 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (415 reviews)
Clean

Reviewed on Oct 13, 2025

Days Inn by Wyndham Perryville
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.6/10 (124 reviews)
This was an overnight trip…Our bathroom was dirty and there weren’t any extra towels or toilet paper in the room. Also the fire alarm went off at 6am without an explanation..They offered yogurt but didn’t have the key to the cabinet.

Reviewed on Aug 11, 2025

Quality Inn Perryville I-55
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
  • 5 min drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
Great place to stay!

Reviewed on Oct 21, 2024

Urban Lofts
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (674 reviews)
Very clean premises, easy check-in, quiet, good breakfast and Wendy, the receptionist was the BEST ever in providing professional, quality and attentive customer service with a smile and warm welcome!

Reviewed on Dec 15, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,008 reviews)
Great location! Great staff well above and beyond. Will definitely stay again.

Reviewed on Dec 21, 2025

Drury Inn & Suites Jackson MO
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (512 reviews)
Everything was good

Reviewed on Dec 13, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr Cape Girardeau MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.4/10 Exceptional! (103 reviews)
Hotel was very clean, quiet and has a great location!

Reviewed on Dec 21, 2025

Tru By Hilton Cape Girardeau
Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG

2.5 out of 5
1301 N Market St Sparta IL
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Sparta. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (370 reviews)
Spotless

Reviewed on Dec 11, 2025

Holiday Inn Express Hotel & Suites Sparta by IHG
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32 Ste Genevieve MO
  • 49 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (610 reviews)
very clean

Reviewed on Nov 29, 2025

Microtel Inn & Suites by Wyndham Sainte Genevieve
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

2.5 out of 5
2150 State Street Chester IL
  • 35 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Chester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (351 reviews)
The hotel has been declining in recent years but the new management is working to make things better and they are doing a great job. Our room was very comfortable and clean. The staff were very friendly and helpful. It was an enjoyable experience and we will stay here again.

Reviewed on Dec 6, 2025

Baymont by Wyndham Chester IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Perryville

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How many hotels are there in Perryville?

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