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Choose from 84 Perryville Hotel Deals

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
2 out of 5
1119 Vincent Dr, Perryville, MO, 63775
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $68 per night from Aug 17 to Aug 18
Stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
4.2/5 Excellent! (535 reviews)
Perryville
"The property was well maintained, bed was very comfortable. If you’re in the area and need a place to stay, I highly recommend."

Reviewed on Aug 8, 2022

Super 8 by Wyndham Perryville
Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
2 out of 5
1500 Liberty Street, Perryville, MO, 63775
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $72 per night from Aug 14 to Aug 15
Stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the overall value ...
3.5/5 Good! (279 reviews)
4 out of 5 stars
"Staff was courteous and friendly. Room was nice for what it was. Smelled like wet animals and the bed base was scratched and peeling. Bed was comfortable and the breakfast was really good."

Reviewed on Jul 17, 2022

Days Inn by Wyndham Perryville
Holiday Inn Express & Suites Perryville, an IHG Hotel
Holiday Inn Express & Suites Perryville, an IHG Hotel
2.5 out of 5
2020 Jefferson St, Perryville, MO, 63775
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $98 per night from Aug 21 to Aug 22
Stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
4.6/5 Exceptional! (245 reviews)
Best hotel!
"We always love staying at this hotel when we come to perryville. Staff is friendly, rooms are comfortable and clean, rarely hear any other guests, pool is nice, breakfast is good."

Reviewed on Jul 25, 2022

Holiday Inn Express & Suites Perryville, an IHG Hotel
Quality Inn
Quality Inn
2.5 out of 5
1517 S. Perryville Blvd., Perryville, MO, 63775
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $72 per night from Aug 28 to Aug 29
Stay at this hotel in Perryville. Enjoy free breakfast, free internet, and free parking. Popular attractions Perryville Country Club and National Shrine of Our ...
3.7/5 Good! (39 reviews)
"Great 1 day stat, clean, quiet, great location & near by stores & restaurants"

Reviewed on Aug 2, 2022

Quality Inn
Urban Lofts
Urban Lofts
3 out of 5
102 N Jackson St, Perryville, MO, 63775
  • 5 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $135 per night from Aug 14 to Aug 15
Stay at this 3-star aparthotel in Perryville. Enjoy free WiFi, free parking, and in-room massages. Popular attractions Perryville Country Club and National Shrine ...
3/5 (2 reviews)
Gorgeous property!!!
"If you are in the area STAY HERE! Hotel price with VIP feel. So many gorgeous details throughout the loft & hospitality is top notch. Mary Janes is a couple minute walk away if you want delicious food and drinks."

Reviewed on Jul 5, 2022

Urban Lofts
Urban Lofts
Urban Lofts
4 out of 5
104 North Jackson Street, Perryville, MO, 63775
  • 5 min drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this 4-star apartment in Perryville. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions Perryville Country Club and National Shrine ...
Urban Lofts
Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL, 62966
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
The price is $104 per night from Aug 17 to Aug 18
Stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions General John A. Logan Museum and ...
4.6/5 Exceptional! (157 reviews)
Great stat
"Always a nice place to stay. Staff very friendly and breakfast always great. Thanks and see you soon"

Reviewed on Aug 7, 2022

Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte Genevieve
2 out of 5
21958 Hwy 32, Ste Genevieve, MO, 63670
  • 49 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $71 per night from Aug 18 to Aug 19
Stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
4.4/5 Excellent! (401 reviews)
"Great shower."

Reviewed on Aug 6, 2022

Microtel Inn & Suites by Wyndham Sainte Genevieve
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO, 63755
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $85 per night from Aug 16 to Aug 17
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
4.7/5 Exceptional! (775 reviews)
"The wifi for guests is quite poor. While the place is nice enough, it is not somewhere to get any work done if you depend on the internet. Rather unfortunate in the year 2022."

Reviewed on Aug 1, 2022

Drury Inn & Suites Jackson MO
Best Western Plus Jackson/Cape Girardeau
Best Western Plus Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO, 63755
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $95 per night from Aug 18 to Aug 19
Stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and an indoor pool. Our guests praise the helpful staff and the clean rooms in ...
4.4/5 Wonderful! (176 reviews)
Great quick overnight stay!
"Extremely clean and quiet (we never saw or heard a single other guest during our quick overnight stay). Everything in the room appeared to be brand new with no signs or wear tear. Left too early to take advantage of breakfast but saw it being set up and there looked to be a lot of options. The two ..."

Reviewed on Aug 2, 2022

Best Western Plus Jackson/Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO, 63755
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $93 per night from Sep 1 to Sep 2
Stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
4.2/5 Very Good! (554 reviews)
Happy!
"Newly remodeled, very clean! Can’t beat the price!"

Reviewed on Jun 21, 2022

Comfort Suites Jackson-Cape Girardeau
SureStay Plus Hotel by Best Western Farmington
SureStay Plus Hotel by Best Western Farmington
2.5 out of 5
1625 W Columbia St, Farmington, MO, 63640
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
The price is $81 per night from Sep 1 to Sep 2
Stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy beds ...
4/5 Very Good! (356 reviews)
"The area was clean. The front desk attendant at check in was absolutely friendly and kind. She was kind enough to let us check out at Noon because we'd traveled so far to be at an appointment super close by but wouldn't been a 2 hour wait instead of just an hour. I'd called the desk to see if they're ..."

Reviewed on Aug 8, 2022

SureStay Plus Hotel by Best Western Farmington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Perryville

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Perryville hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Perryville.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Perryville’s 84 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Perryville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Perryville. No matter your reason for visiting Perryville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Perryville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Perryville for as low as $68.

How many hotels are there in Perryville?

With over 84 hotels in Perryville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in Perryville?

Finding a cheap car rental deal in Perryville is as easy as scoring cheap hotels in Perryville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Perryville now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Perryville right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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