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Southern Illinois

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Southern Illinois Flights as Low as $58

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Aug 4 - Tue, Aug 4
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$58 Roundtrip, found 1 hour ago
$58
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Tue, Aug 4 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 4, priced at $58 found 1 hour ago
Frontier Airlines
Wed, Jul 29 - Sat, Aug 1
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$63 Roundtrip, found 8 hours ago
$63
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 1, priced at $63 found 8 hours ago
Frontier Airlines
Thu, Aug 6 - Wed, Aug 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$66 Roundtrip, found 8 hours ago
$66
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Thu, Aug 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $66 found 8 hours ago
Frontier Airlines
Wed, Aug 5 - Wed, Aug 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 8 hours ago
$68
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $68 found 8 hours ago
Frontier Airlines
Sat, Aug 1 - Wed, Aug 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 8 hours ago
$68
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Aug 1 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $68 found 8 hours ago
Frontier Airlines
Wed, Aug 12 - Fri, Sep 4
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$78 Roundtrip, found 2 days ago
$78
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Sep 4, priced at $78 found 2 days ago
Frontier Airlines
Wed, Aug 12 - Tue, Aug 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$89 Roundtrip, found 8 hours ago
$89
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $89 found 8 hours ago
Delta
Thu, Aug 6 - Fri, Aug 7
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$97 Roundtrip, found 5 days ago
$97
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Aug 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Aug 7, priced at $97 found 5 days ago
Delta
Sun, Aug 30 - Mon, Aug 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$99 Roundtrip, found 8 hours ago
$99
Roundtrip
found 8 hours ago
Select Delta flight, departing Sun, Aug 30 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Aug 31, priced at $99 found 8 hours ago
Frontier Airlines
Thu, Aug 13 - Fri, Sep 4
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$102 Roundtrip, found 8 hours ago
$102
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Thu, Aug 13 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Sep 4, priced at $102 found 8 hours ago
Frontier Airlines
Mon, Aug 3 - Sat, Aug 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$105 Roundtrip, found 8 hours ago
$105
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Mon, Aug 3 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 15, priced at $105 found 8 hours ago
Delta
Sat, Aug 29 - Sat, Aug 29
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$114 Roundtrip, found 8 hours ago
$114
Roundtrip
found 8 hours ago
Select Delta flight, departing Sat, Aug 29 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 29, priced at $114 found 8 hours ago
American Airlines
Wed, Aug 12 - Tue, Aug 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$206 Roundtrip, found 8 hours ago
$206
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $206 found 8 hours ago
Bargain Flight
Tue, Jul 28 - Tue, Aug 4
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$246 Roundtrip, found 2 hours ago
$246
Roundtrip
found 2 hours ago
Select Bargain Flight flight, departing Tue, Jul 28 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 4, priced at $246 found 2 hours ago
Bargain Flight
Wed, Jul 29 - Tue, Aug 4
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$271 Roundtrip, found 3 days ago
$271
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Wed, Jul 29 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Aug 4, priced at $271 found 3 days ago
Delta
Fri, Aug 14 - Sun, Aug 16
ATL
Hartsfield-Jackson Atlanta Intl.
EVV
Evansville Regional
$286 Roundtrip, found 2 hours ago
$286
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Aug 14 from Hartsfield-Jackson Atlanta Intl. to Evansville Regional, returning Sun, Aug 16, priced at $286 found 2 hours ago

Cheap Flights to Southern Illinois

Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southern Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southern Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southern Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Southern Illinois.

What airport is best to fly into Southern Illinois?

When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.

How much are flights to Southern Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $58, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southern Illinois?

The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $58 right now, why wait?

Southern Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$94

Last Minute Hotel Deals in Southern Illinois

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (1,734 reviews)
"The room and staff were excellent. The lady who helps with the breakfast and dinner was very friendly and asked if we needed anything and took our dirty dishes. The staff behind the desk was equally friendly and helpful. It was our 2nd stay at this location."

Reviewed on Jul 17, 2026

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Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
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Drury Inn & Suites St. Louis Fairview Heights
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

2.5 out of 5
150 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
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Best Western St. Louis Fairview Heights
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,003 reviews)
"We really enjoyed our stay at the Drury Inn in O'Fallon. Our boys were able to swim each night. We enjoyed the breakfast (great variety and super helpful staff!) and also the dinner at happy hour. At one point, we couldn't get our key card to work and one of the ladies at the front desk took the ..."

Reviewed on Jul 17, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
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Welcome Suites
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

2.5 out of 5
137 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
6.4/10 (1,004 reviews)
"Arrived at 10pm after driving 5 hours and they told me they were sold out. I had a reservation and I booked it two weeks ahead of time. Expedia got me a room at the holiday inn and it was wonderful"

Reviewed on Jul 17, 2026

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Comfort Suites Fairview Heights - St. Louis
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

3 out of 5
1606 W Fayette Avenue Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Ramada by Wyndham Effingham
See all 1,150 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.