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Southern Illinois

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Southern Illinois Flights as Low as $250

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Aug 12 - Thu, Aug 27
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$250 Roundtrip, found 6 days ago
$250
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Aug 12 from Bradley Intl. to Lambert-St. Louis Intl., returning Thu, Aug 27, priced at $250 found 6 days ago
Frontier Airlines
Wed, Jul 29 - Tue, Aug 11
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$256 Roundtrip, found 6 days ago
$256
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Bradley Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $256 found 6 days ago
Frontier Airlines
Mon, Aug 24 - Thu, Sep 10
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$266 Roundtrip, found 10 hours ago
$266
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Mon, Aug 24 from Norfolk Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $266 found 10 hours ago
Bargain Flight
Wed, Jul 29 - Tue, Aug 4
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$271 Roundtrip, found 5 days ago
$271
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Wed, Jul 29 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Aug 4, priced at $271 found 5 days ago
Frontier Airlines
Wed, Jul 29 - Sat, Aug 15
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$273 Roundtrip, found 6 days ago
$273
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Bradley Intl. to Lambert-St. Louis Intl., returning Sat, Aug 15, priced at $273 found 6 days ago
Frontier Airlines
Mon, Sep 7 - Mon, Sep 21
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$273 Roundtrip, found 6 days ago
$273
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Sep 7 from Norfolk Intl. to Lambert-St. Louis Intl., returning Mon, Sep 21, priced at $273 found 6 days ago
Frontier Airlines
Mon, Aug 24 - Thu, Sep 10
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$275 Roundtrip, found 6 days ago
$275
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Aug 24 from Norfolk Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $275 found 6 days ago
Frontier Airlines
Mon, Jul 27 - Tue, Aug 11
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$277 Roundtrip, found 6 days ago
$277
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Jul 27 from Bradley Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $277 found 6 days ago
Bargain Flight
Fri, Jul 31 - Tue, Aug 4
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$279 Roundtrip, found 6 days ago
$279
Roundtrip
found 6 days ago
Select Bargain Flight flight, departing Fri, Jul 31 from Bradley Intl. to Lambert-St. Louis Intl., returning Tue, Aug 4, priced at $279 found 6 days ago
Bargain Flight
Sun, Aug 16 - Fri, Aug 21
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$281 Roundtrip, found 2 hours ago
$281
Roundtrip
found 2 hours ago
Select Bargain Flight flight, departing Sun, Aug 16 from Norfolk Intl. to Lambert-St. Louis Intl., returning Fri, Aug 21, priced at $281 found 2 hours ago
Frontier Airlines
Wed, Jul 29 - Thu, Aug 6
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$286 Roundtrip, found 6 days ago
$286
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Bradley Intl. to Lambert-St. Louis Intl., returning Thu, Aug 6, priced at $286 found 6 days ago
Frontier Airlines
Wed, Jul 29 - Sun, Aug 9
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$287 Roundtrip, found 6 days ago
$287
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Bradley Intl. to Lambert-St. Louis Intl., returning Sun, Aug 9, priced at $287 found 6 days ago
Frontier Airlines
Mon, Aug 17 - Sun, Sep 6
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Mon, Aug 17 from Bradley Intl. to Lambert-St. Louis Intl., returning Sun, Sep 6, priced at $290 found 6 days ago
Frontier Airlines
Sun, Aug 23 - Thu, Sep 10
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$291 Roundtrip, found 10 hours ago
$291
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Sun, Aug 23 from Norfolk Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $291 found 10 hours ago
Delta
Sun, Sep 6 - Tue, Sep 15
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$324 Roundtrip, found 6 days ago
$324
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Sep 6 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Sep 15, priced at $324 found 6 days ago
American Airlines
Mon, Aug 10 - Sat, Aug 15
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$375 Roundtrip, found 2 hours ago
$375
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Mon, Aug 10 from Norfolk Intl. to Lambert-St. Louis Intl., returning Sat, Aug 15, priced at $375 found 2 hours ago

Cheap Flights to Southern Illinois

Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southern Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southern Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southern Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Southern Illinois.

What airport is best to fly into Southern Illinois?

When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.

How much are flights to Southern Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $250, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southern Illinois?

The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $250 right now, why wait?

Southern Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$231

Last Minute Hotel Deals in Southern Illinois

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (1,743 reviews)
"I liked how clean it was!"

Reviewed on Jul 20, 2026

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Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
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Drury Inn & Suites St. Louis Fairview Heights
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

2.5 out of 5
150 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.8/10 Good! (50 reviews)
"I was double charged due too there system messing up my dates for my stay!!!! I did not get refunded so I had too pay double! On the website I booked for july18-19th and when I arrived they couldn’t find my name and I checked my email and it changed it too july31/august1 and they wouldn’t give me ..."

Reviewed on Jul 19, 2026

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Best Western St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
"Our stay was okay!"

Reviewed on Jul 20, 2026

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Drury Inn & Suites Marion
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,006 reviews)
"Very Nice Stay!! Staff is soo helpful and Cordial. Planning to stay again."

Reviewed on Jul 19, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Super 8 by Wyndham O'Fallon
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

2.5 out of 5
137 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
6.4/10 (1,009 reviews)
"Smells badly, bed was comfy. Rugs need to be replaced. Inside needs an upgrade."

Reviewed on Jul 19, 2026

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Comfort Suites Fairview Heights - St. Louis
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2 out of 5
2431 Old Country Inn Dr Caseyville IL
Stay at this motel in Caseyville. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Pleasant Ridge Park and Cahokia Mounds State ...
6.4/10 (1,002 reviews)
"The room was clean and the air-conditioning worked well."

Reviewed on Jul 20, 2026

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Motel 6 Caseyville, IL - Caseyville Il
See all 1,156 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.