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Southern Illinois

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Southern Illinois Flights as Low as $56

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Sep 30 - Tue, Oct 13
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$56 Roundtrip, found 9 hours ago
$56
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Wed, Sep 30 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Oct 13, priced at $56 found 9 hours ago
Frontier Airlines
Wed, Sep 16 - Wed, Sep 30
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$57 Roundtrip, found 9 hours ago
$57
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Wed, Sep 16 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Sep 30, priced at $57 found 9 hours ago
Frontier Airlines
Mon, Sep 28 - Tue, Oct 13
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$61 Roundtrip, found 9 hours ago
$61
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Mon, Sep 28 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Oct 13, priced at $61 found 9 hours ago
Frontier Airlines
Mon, Sep 14 - Wed, Sep 30
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$62 Roundtrip, found 9 hours ago
$62
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Mon, Sep 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Sep 30, priced at $62 found 9 hours ago
Frontier Airlines
Sat, Sep 26 - Tue, Oct 13
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$66 Roundtrip, found 9 hours ago
$66
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sat, Sep 26 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Oct 13, priced at $66 found 9 hours ago
Frontier Airlines
Sat, Sep 12 - Wed, Sep 30
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$67 Roundtrip, found 9 hours ago
$67
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sat, Sep 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Sep 30, priced at $67 found 9 hours ago
Frontier Airlines
Thu, Sep 17 - Wed, Sep 30
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$71 Roundtrip, found 9 hours ago
$71
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Thu, Sep 17 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Sep 30, priced at $71 found 9 hours ago
Frontier Airlines
Sat, Sep 12 - Mon, Sep 28
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$72 Roundtrip, found 9 hours ago
$72
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sat, Sep 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Sep 28, priced at $72 found 9 hours ago
Frontier Airlines
Thu, Sep 17 - Mon, Sep 28
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$76 Roundtrip, found 9 hours ago
$76
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Thu, Sep 17 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Sep 28, priced at $76 found 9 hours ago
Frontier Airlines
Sun, Sep 27 - Tue, Oct 13
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$77 Roundtrip, found 9 hours ago
$77
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sun, Sep 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Oct 13, priced at $77 found 9 hours ago
Frontier Airlines
Sun, Sep 13 - Wed, Sep 30
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$79 Roundtrip, found 9 hours ago
$79
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sun, Sep 13 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Sep 30, priced at $79 found 9 hours ago
Delta
Tue, Sep 15 - Tue, Sep 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$114 Roundtrip, found 5 days ago
$114
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Sep 15, priced at $114 found 5 days ago
American Airlines
Thu, Aug 27 - Sat, Sep 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$161 Roundtrip, found 18 hours ago
$161
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Thu, Aug 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Sep 12, priced at $161 found 18 hours ago
Bargain Flight
Wed, Aug 5 - Wed, Aug 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$222 Roundtrip, found 9 hours ago
$222
Roundtrip
found 9 hours ago
Select Bargain Flight flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $222 found 9 hours ago
Delta
Fri, Aug 14 - Sun, Aug 23
ATL
Hartsfield-Jackson Atlanta Intl.
EVV
Evansville Regional
$303 Roundtrip, found 18 hours ago
$303
Roundtrip
found 18 hours ago
Select Delta flight, departing Fri, Aug 14 from Hartsfield-Jackson Atlanta Intl. to Evansville Regional, returning Sun, Aug 23, priced at $303 found 18 hours ago
Delta
Sat, Aug 29 - Sat, Sep 12
LAN
Capital Region Intl.
STL
Lambert-St. Louis Intl.
$309 Roundtrip, found 6 hours ago
$309
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, Aug 29 from Capital Region Intl. to Lambert-St. Louis Intl., returning Sat, Sep 12, priced at $309 found 6 hours ago

Cheap Flights to Southern Illinois

Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southern Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southern Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southern Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Southern Illinois.

What airport is best to fly into Southern Illinois?

When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.

How much are flights to Southern Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $56, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southern Illinois?

The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $56 right now, why wait?

Southern Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$56

Last Minute Hotel Deals in Southern Illinois

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Get rates
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,012 reviews)
"Wonderful staff! My go to hotel when we travel down south."

Reviewed on Jul 24, 2026

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Drury Inn & Suites Marion
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
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Drury Plaza Hotel Mt. Vernon
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

2.5 out of 5
150 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.8/10 Good! (55 reviews)
"Upon my arrival I checked in as normal. The reception gave me my room key arriving to my room. I opened the door and someone was already staying in the room that I was checked into. I went back downstairs, spoke with the attendant at the desk and told him someone was already in that room. He apologize ..."

Reviewed on Jul 23, 2026

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Best Western St. Louis Fairview Heights
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

3 out of 5
140 Ludwig Drive Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
6.6/10 (86 reviews)
"The staff was helpful and she was really nice. It was only two problems it had an odor and the stopper didn’t work, but besides that the stay was awesome. The location was the BEST!! You have everything and anything you want and need."

Reviewed on Jul 24, 2026

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Country Inn & Suites by Radisson, Fairview Heights, IL
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Drury Inn & Suites St. Louis O'Fallon, IL
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Super 8 by Wyndham O'Fallon
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

2.5 out of 5
137 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
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Comfort Suites Fairview Heights - St. Louis
See all 1,156 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.