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Hotels in Seneca

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Last Minute Hot Rate® Hotel Deals in Seneca

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Choose from 1255 Seneca Hotel Deals

Days Inn by Wyndham Easley/Greenville/Clemson Area
Days Inn by Wyndham Easley/Greenville/Clemson Area
2 out of 5
121 Days Inn Dr, Easley, SC
  • 58 min drive from Keowee Reservoir
The price is $64 per night from Jun 10 to Jun 11
$64
per night
Jun 10 - Jun 11
Stay at this business-friendly motel in Easley. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
5.8/10 (560 reviews)
"Staff"

Reviewed on May 30, 2023

Days Inn by Wyndham Easley/Greenville/Clemson Area
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $109 per night from Jun 11 to Jun 12
$109
per night
Jun 11 - Jun 12
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (467 reviews)
Great Stay!
"It was great! We only stayed 1 night since we were just passing thru. Clean rooms and comfort beds."

Reviewed on May 29, 2023

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $102 per night from Jul 4 to Jul 5
$102
per night
Jul 4 - Jul 5
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.2/10 Wonderful! (447 reviews)
"The staff was great. Hannah always had a smile and very helpful. The young woman handling the breakfast was wonderful as well"

Reviewed on Jun 4, 2023

Tru by Hilton Seneca Clemson
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $83 per night from Jun 24 to Jun 25
$83
per night
Jun 24 - Jun 25
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (424 reviews)
"Staff was friendly and helpful. Room was clean and everything worked but a little outdated."

Reviewed on May 30, 2023

Quality Inn Seneca US-123
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $129 per night from Jun 9 to Jun 10
$129
per night
Jun 9 - Jun 10
Stay at this business-friendly hotel in Seneca. Enjoy free WiFi, free parking, and a fitness center. Popular attraction Keowee Reservoir is located nearby. Discover ...
9.2/10 Wonderful! (52 reviews)
Great Hotel
"Beautiful views and nice hotel. Breakfast was good. Bed and pillows need improvement"

Reviewed on Jun 6, 2023

Fairfield Inn & Suites Seneca Clemson Univ Area
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $89 per night from Jun 23 to Jun 24
$89
per night
Jun 23 - Jun 24
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (854 reviews)
Great location for Clemson
"Great location for visits to Clemson. Could use a little sprucing up here and there. Complimentary breakfast is a nice way to start the day."

Reviewed on May 14, 2023

Comfort Inn & Suites Clemson - University Area
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $88 per night from Jun 19 to Jun 20
$88
per night
Jun 19 - Jun 20
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
8.2/10 Very Good! (605 reviews)
"Staff were very friendly and responsive."

Reviewed on May 26, 2023

Best Western Plus Clemson Hotel & Conference Center
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
2 out of 5
102 Electric City Blvd, Anderson, SC
  • 42 min drive from Keowee Reservoir
The price is $80 per night from Jun 14 to Jun 15
$80
per night
Jun 14 - Jun 15
Stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8/10 Very Good! (1,004 reviews)
"The front desk attendent was very helpful. Our fold out couch was broken and she promptly moved us to another room."

Reviewed on Jun 1, 2023

Microtel Inn & Suites by Wyndham Anderson/Clemson
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
2 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Keowee Reservoir
The price is $179 per night from Jun 18 to Jun 19
$179
per night
Jun 18 - Jun 19
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast, and valet parking. Popular attractions Larry W. Abernathy Waterfront Park and Fort Hill are located ...
9.8/10 Exceptional! (78 reviews)
"GREAT hotel!! Very clean and very friendly staff."

Reviewed on Jun 5, 2023

The Shepherd Hotel Downtown Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $99 per night from Jun 9 to Jun 10
$99
per night
Jun 9 - Jun 10
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy rooms in ...
8/10 Very Good! (996 reviews)
"Watched college baseball regionals during our stay. Great weekend GO VOLS"

Reviewed on Jun 6, 2023

Inn @ Clemson
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3 out of 5
240 Madren Center Drive, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $149 per night from Jun 9 to Jun 10
$149
per night
Jun 9 - Jun 10
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, a golf course, and breakfast. Our guests praise the restaurant and the helpful staff in our reviews. ...
9.4/10 Exceptional! (588 reviews)
"Really great resort! Super clean and staff is really nice. Would definitely visit again!"

Reviewed on May 30, 2023

Clemson University's James F. Martin Inn
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 17 min drive from Keowee Reservoir
The price is $113 per night from Jun 19 to Jun 20
$113
per night
Jun 19 - Jun 20
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (701 reviews)
"Hotel was nice."

Reviewed on May 7, 2023

Holiday Inn Express & Suites Clemson, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Seneca

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Seneca hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Seneca.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Seneca’s 1,255 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Seneca hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Seneca. No matter your reason for visiting Seneca, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Seneca hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Seneca for as low as $64.

How many hotels are there in Seneca?

With over 1,255 hotels in Seneca, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Seneca?

Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Seneca now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Seneca right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.