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Hotels in Seneca

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Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
  • 11 min drive from Keowee Reservoir
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
Clean room, outdoor fire pit but restaurant closed was hoping for a good meal

Reviewed on Dec 4, 2025

Lakeside Lodge Clemson
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
  • 14 min drive from Keowee Reservoir
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (718 reviews)
Very nice and helpful at the fronte desk. Nice room and very comfortable bed

Reviewed on Nov 30, 2025

Days Inn by Wyndham Seneca / Clemson Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
  • 11 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (788 reviews)
safe

Reviewed on Dec 2, 2025

Tru by Hilton Seneca Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
  • 10 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (664 reviews)
Property, room, and front desk were all very nice. Safety strips in the bathtub would be my only suggestion.

Reviewed on Nov 28, 2025

Quality Inn Seneca Clemson Area US-123
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
  • 7 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (660 reviews)
X

Reviewed on Nov 29, 2025

Hampton Inn & Suites Seneca-Clemson Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
  • 8 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (637 reviews)
The stay was amazing

Reviewed on Dec 1, 2025

Best Western Seneca-Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123 Seneca SC
  • 10 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (204 reviews)
Very

Reviewed on Oct 18, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
  • 20 min drive from Keowee Reservoir
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.6/10 Exceptional! (49 reviews)
The cabin was very cozy.

Reviewed on Nov 4, 2025

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
  • 43 min drive from Keowee Reservoir
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,003 reviews)
I always love when work leads me to this town because right in the heart of it all sits this hidden home like gem. Ive stayed here a few times and its always my top pick when coming to Anderson. I checked in tonight & was actually offered an upgrade, i took the offer not knowing i was stepping in ...

Reviewed on Dec 9, 2025

Days Inn by Wyndham Anderson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
  • 16 min drive from Keowee Reservoir
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
Everything was good except the bacon. Please make crispier

Reviewed on Dec 2, 2025

Best Western Plus Clemson Hotel & Conference Center
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
  • 16 min drive from Keowee Reservoir
Stay at this cottage in Clemson. Enjoy air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy Waterfront Park are ...
Wooded Cottage - 3 Mi to Clemson University
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
  • 15 min drive from Keowee Reservoir
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (736 reviews)
Clean room, friendly staff 2nd floor a bit loud with the bar upstairs and chairs moving across the floor (ceiling of room)

Reviewed on Dec 2, 2025

The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Seneca

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Frequently Asked Questions About Seneca hotels

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How many hotels are there in Seneca?

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