Search for Cheap Deals on
Winery Hotels in Durham

Check Last Minute Durham Hotel Deals

Tonight Sep 26 - Sep 27This weekend Sep 26 - Sep 28

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured Durham Winery Hotels

The Durham Hotel

The Durham Hotel

4 out of 5
315 East Chapel Hill Street, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Durham. Enjoy free WiFi, 2 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
The Durham Hotel
Durham Marriott City Center

Durham Marriott City Center

3.5 out of 5
201 Foster St, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Durham. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
Durham Marriott City Center
21c Museum Hotel Durham

21c Museum Hotel Durham

4 out of 5
111 North Corcoran Street, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in Durham. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. ...
21c Museum Hotel Durham
Aloft Durham Downtown

Aloft Durham Downtown

3 out of 5
345 Blackwell Street, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Durham. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in ...
Aloft Durham Downtown
Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr

3 out of 5
1108 West Main Street, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Durham. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff in our reviews. ...
Residence Inn Durham McPherson/Duke University Medical Cntr
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

2.5 out of 5
1542 North Gregson Street, Durham, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Durham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Hampton Inn & Suites Durham/North I-85
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

3 out of 5
2102 West Main Street, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Durham. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hilton Garden Inn Durham/University Medical Center
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

2 out of 5
502 Elf St, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Durham. Enjoy free WiFi, a free area shuttle, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
University Inn Durham next to Duke University Medical Center
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

3 out of 5
2306 Elba St, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Durham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
The Lodge at Duke Medical Center
Super 8 by Wyndham Durham/University Area NC

Super 8 by Wyndham Durham/University Area NC

2 out of 5
2337 Guess Rd, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this motel in Durham. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Duke Homestead and Northgate Mall are located nearby.
Super 8 by Wyndham Durham/University Area NC
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

2.5 out of 5
2516 Guess Rd, Durham, NC
Fully refundable
Book a stay at this business-friendly hotel in Durham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Holiday Inn Express Durham by IHG
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

2 out of 5
1915 N Pointe Drive, Durham, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Durham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Red Roof Inn Durham - Duke Univ Medical Center
See all 782 properties in Durham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.