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South Carolina from $109

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Cheap round-trip flights to South Carolina

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Flights to South Carolina starting at $109

Have you been telling yourself, “2025 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to South Carolina is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in South Carolina that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to South Carolina? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to South Carolina by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to South Carolina. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $109 to $367.
  • Duration: Want to get to South Carolina as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to South Carolina today and get going.

Last Minute Hotel Deals in South Carolina

Emeline

Emeline

4 out of 5
181 Church St, Charleston, SC
Stay at this 4-star luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the bar in ...
9.2/10 Wonderful! (1,675 reviews)
"The walls are extremely thin, so we could hear the folks in the room next door as well as we would have if they had been in our room. We thoroughly enjoyed the location of the hotel and its accessibility to shopping, the historic district and restaurants. The staff were professional, upbeat, and ..."

Reviewed on Oct 17, 2025

Opens in a new windowEmeline
Sea Crest Oceanfront Resort

Sea Crest Oceanfront Resort

3 out of 5
803 S Ocean Blvd, Myrtle Beach, SC
Stay at this 3-star beach aparthotel in Myrtle Beach. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the pool and the bar in our reviews. ...
7.8/10 Good! (4,628 reviews)
"Pool was very clean"

Reviewed on Oct 17, 2025

Opens in a new windowSea Crest Oceanfront Resort
Holiday Inn Charleston Riverview by IHG

Holiday Inn Charleston Riverview by IHG

3 out of 5
301 Savannah Hwy, Charleston, SC
Stay at this 3-star business-friendly hotel in Charleston. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the bar in ...
8/10 Very Good! (1,022 reviews)
"Checking in was wonderful, went over everything with shuttle time, provided maps. I will stay here again. The breakfast was great and the view on the Roof was stunning!"

Reviewed on Oct 16, 2025

Opens in a new windowHoliday Inn Charleston Riverview by IHG
Save an average of 15% on thousands of hotels when you're signed in
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

4 out of 5
130 Shipyard Drive, Hilton Head Island, SC
Stay at this 4-star beach hotel in Hilton Head Island. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,117 reviews)
"Love it"

Reviewed on Oct 16, 2025

Opens in a new windowSonesta Resort Hilton Head Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.