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Florence Regional

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Cheap Flights to Florence Regional

Fall in love at first flight with your vacation to Florence Regional by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence Regional on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence Regional, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence Regional

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence Regional with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Florence Regional?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence Regional are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence Regional?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Florence Regional.

What airport is best to fly into Florence Regional?

When you’re planning your trip to Florence Regional, convenience is the name of the game. Luckily, Florence Regional Myrtle Beach Intl. Airport is nearby so you can deplane and get going on checking off everything on your Florence Regional must-do list.

How much are flights to Florence Regional?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence Regional on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence Regional?

The trick to saving a stack of cash on your flight to Florence Regional? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Florence Regional Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO

Last Minute Hotel Deals in Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,009 reviews)
Only stayed for a night, but everything was excellent.

Reviewed on Jan 4, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (611 reviews)
Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return.

Reviewed on Dec 23, 2025

Hotel Florence, Tapestry Collection by Hilton
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,532 reviews)
Only issue was frayed carpet and small tv. Loved mattress and quiet location.

Reviewed on Jan 4, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,234 reviews)
The stay was beautiful

Reviewed on Jan 3, 2026

Park Inn by Radisson Florence, SC
Best Western Inn

Best Western Inn

2.5 out of 5
1808 W Lucas Street Florence SC
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Dr. ...
7.6/10 Good! (1,005 reviews)
Good clean room and staff

Reviewed on Jan 1, 2026

Best Western Inn
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2 out of 5
1832 1/2 Lucas Street, I95 Exit 164 Florence SC
Stay at this motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
6.8/10 (1,004 reviews)
The staff was friendly.

Reviewed on Jan 3, 2026

Super 8 by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,688 reviews)
Staff was courteous and efficient, room was well kept and comfortable.

Reviewed on Jan 3, 2026

La Quinta Inn & Suites by Wyndham Florence
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 out of 5
2140 West Lucas Street Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,007 reviews)
My room was very spacious and clean and i enjoyed the surround sound tv and the floors and bathroom were clean. The staff was very nice.

Reviewed on Jan 5, 2026

Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.