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About South Carolina

Hotwire offers flights to South Carolina to meet every traveler's needs. Whatever your flight need - Hotwire has the flight for you. So choose from flights to South Carolina or destinations around the world and discover how easy it is to make your flight reservations on Hotwire.

Airports in South Carolina

  • Myrtle Beach, SC (MYR) (MYR)
  • Charleston Intl. (CHS)
  • Columbia Metropolitan (CAE)
  • Greenville-Spartanburg Intl. (GSP)
  • Hilton Head Island, SC (HHH) (HHH)
  • Florence Regional (FLO)
  • Spartanburg Downtown Memorial (SPA)
  • Greenville Downtown (GMU)
  • Sumter Municipal (SUM)
  • Anderson County Regional (AND)
  • Rock Hill-York County (RKH)
  • Georgetown County (GGE)

Explore South Carolina

Heading to South Carolina? Explore South Carolina with Expedia's Travel Guides to find the best hotels, city breaks, car hire deals and more!

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