About South Carolina

Hotwire offers flights to South Carolina to meet every traveler's needs. Whatever your flight need - Hotwire has the flight for you. So choose from flights to South Carolina or destinations around the world and discover how easy it is to make your flight reservations on Hotwire.

Airports in South Carolina

  • Charleston Intl. (CHS)
  • Myrtle Beach, SC (MYR) (MYR)
  • Columbia Metropolitan (CAE)
  • Greenville-Spartanburg Intl. (GSP)
  • Hilton Head Island, SC (HHH) (HHH)
  • Florence Regional (FLO)
  • Greenville Downtown (GMU)
  • Spartanburg Downtown Memorial (SPA)
  • Rock Hill-York County (RKH)
  • Oconee County Regional (CEU)
  • Sumter Municipal (SUM)
  • Anderson County Regional (AND)

Explore South Carolina

Heading to South Carolina? Explore South Carolina with Expedia's Travel Guides to find the best hotels, city breaks, car hire deals and more!

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