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Tenderloin Vacations

Pack those stellar shades. We have Tenderloin vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Tenderloin – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Tenderloin vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Tenderloin

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Tenderloin vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Tenderloin well.

Tenderloin Flight + Hotel packages

Top Hotel Deals

See all 687 Hotels in Tenderloin
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
    4.0 out of 5.0
     
     

    The Asian-inspired Hotel Nikko San Francisco is located downtown, a 4-minute walk from Union Square and the designer shops of Westfield San Francisco Centre. ...

    Hotel Nikko San Francisco$194

    Hotel Nikko San Francisco$194
    Hotel Spero

    Hotel Spero

    405 Taylor St, San Francisco
      4.0 out of 5.0
       
       

      The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks from the Powell Street cable car.

      Hotel Spero$159

      Hotel Spero$159
      Clift

      Clift

      495 Geary St, San Francisco
        4.0 out of 5.0
         
         

        Old-world elegance is suffused with modern glamour in this historic San Francisco hotel 2 blocks from Union Square, a half-mile from the Financial District, ...

        Clift$195

        Clift$195
        Parc 55 San Francisco - A Hilton Hotel

        Parc 55 San Francisco - A Hilton Hotel

        55 Cyril Magnin St, San Francisco
          4.0 out of 5.0
           
           

          Just off Market Street, downtown San Francisco's major thoroughfare, this contemporary 32-story hotel is 1 block from San Francisco Centre shops and 3 blocks ...

          Parc 55 San Francisco - A Hilton Hotel$161

          Parc 55 San Francisco - A Hilton Hotel$161
          Handlery Union Square Hotel

          Handlery Union Square Hotel

          351 Geary St, San Francisco
            3.5 out of 5.0
             
             

            A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the San Francisco Museum of Modern ...

            Handlery Union Square Hotel$149

            Handlery Union Square Hotel$149
            Tilden Hotel

            Tilden Hotel

            345 Taylor St, San Francisco
              4.0 out of 5.0
               
               

              The updated 1928 San Francisco hotel is blocks from Union Square and the Tenderloin which are set in the heart of the Downtown district. This area is a hub for ...

              Tilden Hotel$134

              Tilden Hotel$134
              Staypineapple at The Alise San Francisco

              Staypineapple at The Alise San Francisco

              580 Geary St, San Francisco
                4.0 out of 5.0
                 
                 

                Built in 1913, this handsomely updated boutique hotel is in the midst of San Francisco's Union Square district, 2 blocks from the Curran and ACT theaters, and ...

                Staypineapple at The Alise San Francisco$148

                Staypineapple at The Alise San Francisco$148
                Hilton San Francisco Union Square

                Hilton San Francisco Union Square

                333 O'Farrell St., San Francisco
                  4.0 out of 5.0
                   
                   

                  Iconic, AAA 4-Diamond hotel a few steps from Union Square, Cable Car station, theatre district, BART, Chinatown, SFMOMA, and Moscone Center. Upgraded rooms offer ...

                  Hilton San Francisco Union Square$161

                  Hilton San Francisco Union Square$161
                  Hotel Fusion, a C-Two Hotel

                  Hotel Fusion, a C-Two Hotel

                  140 Ellis Street, San Francisco
                    3.5 out of 5.0
                     
                     

                    Cable cars and the historic F-line streetcar stop just a block from the friendly Hotel Fusion; Union Square, major theaters, and the Westfield San Francisco ...

                    Hotel Fusion, a C-Two Hotel$139

                    Hotel Fusion, a C-Two Hotel$139
                    Hotel G San Francisco

                    Hotel G San Francisco

                    386 Geary Street, San Francisco
                      4.0 out of 5.0
                       
                       

                      This hotel is one block from shopping at Union Square, theaters, and historic cable cars, and less than a mile from San Francisco's MOMA, Financial District, ...

                      Hotel G San Francisco$146

                      Hotel G San Francisco$146

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.