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South San Francisco Vacations

Pack those stellar shades. We have South San Francisco vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to South San Francisco – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with South San Francisco vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to South San Francisco

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great South San Francisco vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows South San Francisco well.

South San Francisco Flight + Hotel packages

Top Hotel Deals

See all 723 Hotels in South San Francisco
Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd, South San Francisco
    2.0 out of 5.0
     
     

    This 200-room hotel is 2 miles north of San Francisco International Airport and 10 miles from downtown San Francisco.

    Travelodge by Wyndham San Francisco Airport North$67

    Travelodge by Wyndham San Francisco Airport North$67
    Best Western Plus Grosvenor Airport Hotel

    Best Western Plus Grosvenor Airport Hotel

    380 S Airport Boulevard, South San Francisco
      3.0 out of 5.0
       
       

      This high-rise hotel offers: complimentary shuttle service to and from the San Francisco airport, less than 2 miles away; easy access to downtown via BART connection ...

      Best Western Plus Grosvenor Airport Hotel$112

      Best Western Plus Grosvenor Airport Hotel$112
      Park Pointe Hotel

      Park Pointe Hotel

      245 S Airport Blvd, South San Francisco
        2.0 out of 5.0
         
         

        Ideal for a comfortable layover, Park Pointe Hotel places guests 1 mile (0.6 km) north of San Francisco International Airport. The hotel’s free shuttle gets ...

        Park Pointe Hotel$114

        Park Pointe Hotel$114
        Embassy Suites San Francisco Airport - South San Francisco

        Embassy Suites San Francisco Airport - South San Francisco

        250 Gateway Blvd, South San Francisco
          3.5 out of 5.0
           
           

          SFO airport is only 3 miles away, and there's a free trolley to downtown San Francisco on Fridays and Saturdays.

          Embassy Suites San Francisco Airport - South San Francisco$110

          Embassy Suites San Francisco Airport - South San Francisco$110
          La Quinta Inn & Suites San Francisco Airport North

          La Quinta Inn & Suites San Francisco Airport North

          20 Airport Blvd, South San Francisco
            2.5 out of 5.0
             
             

            2 blocks from the South San Francisco Conference Center and 1 mile from the airport, this hotel offers complimentary airport transportation, and downtown San ...

            La Quinta Inn & Suites San Francisco Airport North$109

            La Quinta Inn & Suites San Francisco Airport North$109
            Holiday Inn San Francisco International Airport

            Holiday Inn San Francisco International Airport

            275 S Airport Blvd, South San Francisco
              3.0 out of 5.0
               
               

              Located less than 3 miles from San Francisco International Airport, this South San Francisco hotel is also within 17 miles of the Golden Gate Bridge.

              Holiday Inn San Francisco International Airport$102

              Holiday Inn San Francisco International Airport$102
              Hotel Focus SFO

              Hotel Focus SFO

              111 Mitchell Ave, South San Francisco
                3.0 out of 5.0
                 
                 

                Hotel Focus SFO is 3 miles (4.8 km) from San Francisco International Airport and a 15-minute walk from So. California Caltrain Station. It's a half-hour drive ...

                Hotel Focus SFO$116

                Hotel Focus SFO$116
                Larkspur Landing South San Francisco - An All-Suite Hotel

                Larkspur Landing South San Francisco - An All-Suite Hotel

                690 Gateway Blvd, South San Francisco
                  3.0 out of 5.0
                   
                   

                  This all-suite hotel is conveniently located on a quiet street in an office park in South San Francisco, less than 4 miles from San Francisco International ...

                  Larkspur Landing South San Francisco - An All-Suite Hotel$127

                  Larkspur Landing South San Francisco - An All-Suite Hotel$127
                  Courtyard by Marriott SFO - Oyster Point Waterfront

                  Courtyard by Marriott SFO - Oyster Point Waterfront

                  1300 Veterans Way, South San Francisco
                    3.0 out of 5.0
                     
                     

                    Off Highway 101, this waterfront hotel is in South San Francisco, 3 miles from San Francisco International Airport (SFO) and Cow Palace. Downtown San Francisco ...

                    Courtyard by Marriott SFO - Oyster Point Waterfront$127

                    Courtyard by Marriott SFO - Oyster Point Waterfront$127
                    Hilton Garden Inn San Francisco Airport North

                    Hilton Garden Inn San Francisco Airport North

                    670 Gateway Blvd, South San Francisco
                      3.0 out of 5.0
                       
                       

                      Hilton Garden Inn San Francisco Airport North is 2 minutes by free shuttle from San Francisco International Airport. It’s a 10-minute walk to the BART metro ...

                      Hilton Garden Inn San Francisco Airport North$111

                      Hilton Garden Inn San Francisco Airport North$111

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.