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Perryville Vacations

Pack those stellar shades. We have Perryville vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Perryville – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Perryville vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Perryville

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Perryville vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Perryville well.

Top Hotel Deals

See all 33 Hotels in Perryville
Holiday Inn Express & Suites Perryville

Holiday Inn Express & Suites Perryville

2020 Jefferson St, Perryville
    2.5 out of 5.0
     
     

    Situated in Perryville, this hotel is close to Perryville Country Club and National Shrine of Our Lady of the Miraculous Medal.

    Holiday Inn Express & Suites Perryville$119

    Holiday Inn Express & Suites Perryville$119
    Microtel Inn & Suites by Wyndham Sainte Genevieve

    Microtel Inn & Suites by Wyndham Sainte Genevieve

    21958 Hwy 32, Ste Genevieve
      2.0 out of 5.0
       
       

      Located in the heart of Ste Genevieve, this hotel is within 25 mi (40 km) of Elzie C. Segar Memorial Park, National Shrine of Our Lady of the Miraculous Medal, ...

      Microtel Inn & Suites by Wyndham Sainte Genevieve$67

      Microtel Inn & Suites by Wyndham Sainte Genevieve$67
      Super 8 by Wyndham Perryville

      Super 8 by Wyndham Perryville

      1119 Vincent Dr, Perryville
        2.0 out of 5.0
         
         

        Situated in Perryville, this motel is 0.9 mi (1.5 km) from Perryville Country Club and 1.7 mi (2.8 km) from National Shrine of Our Lady of the Miraculous Medal. ...

        Super 8 by Wyndham Perryville$88

        Super 8 by Wyndham Perryville$88
        Days Inn by Wyndham Perryville

        Days Inn by Wyndham Perryville

        1500 Liberty Street, Perryville
          2.0 out of 5.0
           
           

          Situated in Perryville, this hotel is 1.1 mi (1.8 km) from Perryville Country Club and 1.9 mi (3.1 km) from National Shrine of Our Lady of the Miraculous Medal. ...

          Days Inn by Wyndham Perryville$70

          Days Inn by Wyndham Perryville$70
          Quality Inn

          Quality Inn

          1400 W Liberty St, Farmington
            2.5 out of 5.0
             
             

            Located in the heart of Farmington, this hotel is within 9 mi (15 km) of Crown Pointe Golf Club, Columbia Park, and Missouri Mines State Historic Site. Fort ...

            Quality Inn$60

            Quality Inn$60
            Comfort Inn Festus

            Comfort Inn Festus

            1303 Veterans Blvd, Festus
              2.5 out of 5.0
               
               

              Situated in Festus, this hotel is within 20 mi (32 km) of Mastodon State Historic Site, Sunridge Park, and Persimmon Ridge Winery. Suson Park and Swing-A-Round ...

              Comfort Inn Festus$92

              Comfort Inn Festus$92
              Holiday Inn Express & Suites Farmington

              Holiday Inn Express & Suites Farmington

              820 Market St, Farmington
                2.5 out of 5.0
                 
                 

                Situated in Farmington, this hotel is 2 mi (3.2 km) from Crown Pointe Golf Club and within 9 mi (15 km) of Columbia Park and Missouri Mines State Historic Site. ...

                Holiday Inn Express & Suites Farmington$107

                Holiday Inn Express & Suites Farmington$107
                La Quinta Inn & Suites Festus - St. Louis South

                La Quinta Inn & Suites Festus - St. Louis South

                1001 Veterans Blvd, Festus
                  2.5 out of 5.0
                   
                   

                  Situated in a rural location, this hotel is within 20 mi (32 km) of Mastodon State Historic Site, Sunridge Park, and Persimmon Ridge Winery. Suson Park and Swing-A-Round ...

                  La Quinta Inn & Suites Festus - St. Louis South$108

                  La Quinta Inn & Suites Festus - St. Louis South$108
                  Super 8 by Wyndham Farmington

                  Super 8 by Wyndham Farmington

                  930 Valley Creek Dr, Farmington
                    2.0 out of 5.0
                     
                     

                    Situated in Farmington, this motel is 2.2 mi (3.5 km) from Crown Pointe Golf Club and within 9 mi (15 km) of Columbia Park and Missouri Mines State Historic ...

                    Super 8 by Wyndham Farmington$54

                    Super 8 by Wyndham Farmington$54
                    Quality Inn

                    Quality Inn

                    1200 W Gannon Dr, Festus
                      3.0 out of 5.0
                       
                       

                      Situated in the business district, this hotel is within 20 mi (32 km) of Mastodon State Historic Site, Sunridge Park, and Persimmon Ridge Winery. Kennedy Rink ...

                      Quality Inn$84

                      Quality Inn$84

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.