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Choose from 3019 Northeast Missouri Hotel Deals
Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport
Renaissance St. Louis Airport Hotel
"The staff is so nice!"
Reviewed on Sep 13, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
"Close to venues for concerts for walking distance. Parking was on-site. We were early enough to get a spot, but it's shared with the public, Eclectic little spot, loved it."
Reviewed on Sep 13, 2026
Drury Plaza Hotel St. Louis Union Station
21C Museum Hotel St Louis
"Nice place but very disappointing"
Reviewed on Sep 14, 2026
Pear Tree Inn St. Louis Near Union Station
"Hotel is a bit old and could use a refresher and deeper clean. Location was great, right next to soccer stadium, 30 min walk to the baseball stadium, and 20 min walk to city museum. Breakfast was good and it was nice to have snacks and drinks in the evening."
Reviewed on Sep 13, 2026
Hollywood Casino & Hotel St. Louis
"Clean Bed was sooo comfy"
Reviewed on Sep 13, 2026
Sonesta ES Suites St. Louis - Chesterfield
"The staff was friendly but the room was pretty rough. The room smelled musty, the dead bolt was broke on the door, and we had blood spots on the mirror by the bathroom."
Reviewed on Sep 13, 2026
Home2 Suites by Hilton St. Louis Downtown
"Everything and everyone was good"
Reviewed on Sep 12, 2026
Live by Loews - St.Louis
"Very clean, close to ballpark village,very friendly staff"
Reviewed on Sep 14, 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day ..."
Reviewed on Sep 10, 2026
Find cheap hotels in Northeast Missouri
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Northeast Missouri.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Northeast Missouri’s 3,019 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $106. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Northeast Missouri hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Northeast Missouri. No matter your reason for visiting Northeast Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Northeast Missouri hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Northeast Missouri?
With over 3,019 hotels in Northeast Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $106.
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- Downtown St. Louis Hotels
- Clayton Hotels
- Central West End Hotels
- Creve Coeur Hotels
- St. Charles Historic District Hotels
- Soulard Hotels
- University City Hotels
- Ladue Hotels
- The Grove Hotels
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- Botanical Heights Hotels
- Kosciusko Hotels
- Laclede's Landing Hotels
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- Hotels near St. Louis Union Station
- Hotels near St. Louis Zoo
- Hotels near Enterprise Center
- Hotels near Busch Stadium
- Hotels near Dome at America’s Center
- Hotels near Washington University in St. Louis
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- Hotels near Forest Park
- Hotels near Six Flags St. Louis
- Hotels near America's Center Convention Complex
- Hotels near Mississippi River
- Hotels near Barnes Jewish Hospital
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- Hotels near Westport Plaza
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St Charles Convention Center
- Hotels near Saint Louis Galleria Mall
- Hotels near Meramec Caverns
- Hotels near Magic House - St. Louis Children's Museum
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- Columbia Hotels
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- Alton Hotels
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- Ozarks Hotels
- Fenton Hotels
- Wentzville Hotels
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