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Hotels in Hannibal

Choose from 173 Hannibal Hotel Deals

Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 7 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,011 reviews)
This was an amazing overall stay, we loved that it was within walking distance of everything we wanted access to. The pool is in the main lobby of the hotel which was interesting but no big deal. We did purchase some drinks from the gift shop area and paid with our card and almost got charged again ...

Reviewed on Mar 23, 2026

Best Western On The River
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,007 reviews)
No question the nicest motel in the price range that we paid. Breakfast was better than any other motel that we’ve previously stayed in that price range. And the motel was much nicer.

Reviewed on Mar 23, 2026

Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
Pam who checked us in I think, was wonderful.

Reviewed on Mar 24, 2026

Sleep Inn & Suites Hannibal West
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Book a stay at this family-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.4/10 (746 reviews)
Great

Reviewed on Mar 20, 2026

Baymont by Wyndham Hannibal
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (679 reviews)
The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location.

Reviewed on Mar 15, 2026

Comfort Inn & Suites - Hannibal
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,003 reviews)
Pool closed, looked pretty permanent but was told closed for maintenance. That was disappointing, I picked the place partly because it had a pool. Hannibal is great to explore. Motel 6 was just a place to sleep one night & shower so the place was fine for that.

Reviewed on Mar 24, 2026

Motel 6 Hannibal, MO
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,002 reviews)
Very clean with friendly staff and a very reasonable price. We’ve spent a lot more on hotels that didn’t come close to this one in cleanliness. Will definitely stay here again if we are ever in the area.

Reviewed on Mar 22, 2026

Super 8 by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 7 min drive from Mark Twain Cave
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
8.8/10 Excellent! (25 reviews)
Nice room. Matched the pictures. Exactly what we were looking for.

Reviewed on Jan 18, 2026

Lighthouse Inn & Suites
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (159 reviews)
Yes pet friendly only charge$10 / night for your pet. A/C was very cold . Pool is nice breakfast is good friendly accommodating staff . One of the best places in town my favorite

Reviewed on Mar 24, 2026

Howard Johnson BY Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (227 reviews)
Clean room. Comfortable bed. The staff were friendly. Convenient on/off location.

Reviewed on Mar 15, 2026

Days Inn by Wyndham Hannibal
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
111 Bird St Hannibal MO
  • 7 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.4/10 Exceptional! (170 reviews)
Great value .. excellent amentities and location... Very comfortable

Reviewed on Mar 17, 2026

Riverside Inn Hannibal
Holiday Inn Express & Suites Hannibal - Medical Center by IHG

Holiday Inn Express & Suites Hannibal - Medical Center by IHG

2.5 out of 5
120 Shinn Lane Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Hannibal - Medical Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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How many hotels are there in Hannibal?

With over 173 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

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