Search for Cheap Deals on
Hotels in Hannibal

Choose from 179 Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 8 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,013 reviews)
Great hotel.. one of the nicer ones in Hannibal… hope you like cameras because they have a lot of them… friendly staff, safe place to stay.

Reviewed on May 11, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 4 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,014 reviews)
Right downtown, restaurants in walking distance.. pool was cool, dated property.. parking available and safe place to stay. We would stay again

Reviewed on May 11, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 4 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,003 reviews)
beds are hard and lumpy. the young man gave us the room closest to the lobby so you heard everyone which woke me up quite a few times.

Reviewed on May 10, 2026

Motel 6 Hannibal, MO
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 8 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,002 reviews)
Clean , comfortable, safe , good bfast . Friendly and happy employees. Highly recommended!

Reviewed on May 7, 2026

Sleep Inn & Suites Hannibal West
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 5 min drive from Mark Twain Cave
Book a stay at this family-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.4/10 (763 reviews)
For the price it doesn’t get much better. Rooms are clean and the front desk guy will truly brighten your day. The outside, is dated. The layout of the hotel is odd, and there is this massive indoor pool that connects each wing of the hotel. I bet in the 70s this place was awesome lol. The new owners ...

Reviewed on May 7, 2026

Baymont by Wyndham Hannibal
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 5 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (690 reviews)
Very clean hotel, nothing fancy but everything was very nice. Would recommend.

Reviewed on Apr 28, 2026

Comfort Inn & Suites - Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 5 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.4/10 Good! (236 reviews)
Light and lamp in bathroom sounded like a freight train coming through the wall and the yard was not maintained and was long even for pets to potty. The fridge sounded rattled all night long. The breakfast and bed were amazing.

Reviewed on May 9, 2026

Days Inn by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 5 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (166 reviews)
The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful

Reviewed on May 6, 2026

Howard Johnson BY Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 5 min drive from Mark Twain Cave
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
9/10 Wonderful! (27 reviews)
AMAZING PLACE! Everything was incredible. Bed was comfortable, tv was large, hot tub big enough for 2, shower was gorgeous, decor was just top notch. This hidden gem needs more attention!

Reviewed on May 3, 2026

Lighthouse Inn & Suites
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 4 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,003 reviews)
Yes

Reviewed on May 11, 2026

Super 8 by Wyndham Hannibal
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
111 Bird St Hannibal MO
  • 4 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.4/10 Exceptional! (172 reviews)
No check-in instructions!!!! Very expensive! Other wise OK

Reviewed on Apr 14, 2026

Riverside Inn Hannibal
Garden House Bed and Breakfast

Garden House Bed and Breakfast

2 out of 5
301 N 5th St Hannibal MO
  • 4 min drive from Mark Twain Cave
Stay at this B&B in Hannibal. Enjoy free parking, breakfast (surcharge), and bathrobes. Popular attractions Big River Train Town and Jim's Journey: The Huck ...
8.4/10 Very Good! (43 reviews)
Our room was delightful. The bath was down the hall but not inconvenient. We did not select the breakfast option. We did not have the opportunity on this trip to partake of the nearby shops.

Reviewed on Apr 28, 2026

Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Hannibal hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Hannibal.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Hannibal’s 179 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Hannibal hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Hannibal. No matter your reason for visiting Hannibal, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Hannibal hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Hannibal for as low as $69.

How many hotels are there in Hannibal?

With over 179 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Hannibal?

Finding a cheap car rental deal in Hannibal is as easy as scoring cheap hotels in Hannibal. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.