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Tonight Dec 9 - Dec 10Next weekend Dec 15 - Dec 17

Choose from 126 Hannibal Hotel Deals

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
The price is $48 per night from Jan 1 to Jan 2
$48
per night
Jan 1 - Jan 2
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (981 reviews)
"Very bare bones. Almost no amenities. Not even a box of Kleenex. It was clean and quiet, tho, and the staff was very nice. Didn't use the shower, so can't comment on that. Pool was closed, and the pop machine was out of order. All in all, it was good for the price. If you're just looking for a comfy ..."

Reviewed on Nov 30, 2023

Motel 6 Hannibal, MO
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $67 per night from Dec 26 to Dec 27
$67
per night
Dec 26 - Dec 27
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,000 reviews)
"Very nice hotel. Very clean. Wonderful breakfast. Nice two room suite. Highly recommended"

Reviewed on Dec 4, 2023

Quality Inn & Suites Hannibal
Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 1 min walk from Mark Twain Boyhood Home and Museum
The price is $97 per night from Dec 10 to Dec 11
$97
per night
Dec 10 - Dec 11
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,000 reviews)
"Clean and safe"

Reviewed on Dec 3, 2023

Best Western On The River
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $101 per night from Dec 10 to Dec 11
$101
per night
Dec 10 - Dec 11
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (864 reviews)
"Friendly staff and clean hotel. Breakfast was great."

Reviewed on Nov 27, 2023

Sleep Inn & Suites
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
The price is $56 per night from Dec 10 to Dec 11
$56
per night
Dec 10 - Dec 11
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (999 reviews)
"It was close"

Reviewed on Nov 14, 2023

Super 8 by Wyndham Hannibal
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 5 min drive from Mark Twain Boyhood Home and Museum
The price is $81 per night from Dec 17 to Dec 18
$81
per night
Dec 17 - Dec 18
Stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (416 reviews)
"Tv didnt work in first room, however staff promptly switched our room. Second room, tub didnt drain properly but again staff was attentive to us when we notified them. Staff was friendly and kind and made the minor inconveniences less of a bother. Would recommend."

Reviewed on Nov 27, 2023

Comfort Inn & Suites - Hannibal
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
2.5 out of 5
120 Shinn Lane, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $121 per night from Dec 21 to Dec 22
$121
per night
Dec 21 - Dec 22
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (354 reviews)
"Excellent place."

Reviewed on Dec 3, 2023

Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $57 per night from Dec 26 to Dec 27
$57
per night
Dec 26 - Dec 27
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (496 reviews)
"Its a great place to stay"

Reviewed on Nov 5, 2023

Baymont by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2.5 out of 5
4141B MARKET ST, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (54 reviews)
"able to park at our room door"

Reviewed on Nov 20, 2023

Howard Johnson BY Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $61 per night from Dec 10 to Dec 11
$61
per night
Dec 10 - Dec 11
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sodalis Nature Preserve and Rockcliffe ...
6.8/10 (35 reviews)
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"Comfortable"

Reviewed on Nov 19, 2023

Days Inn by Wyndham Hannibal
Main Street Bed & Breakfast
Main Street Bed & Breakfast
3.5 out of 5
Corner of Main and Center, 201 North Main, Hannibal, MO
  • 2 min walk from Mark Twain Boyhood Home and Museum
The price is $125 per night from Dec 12 to Dec 13
$125
per night
Dec 12 - Dec 13
Stay at this 3.5-star B&B in Hannibal. Enjoy free parking, internet, and daily housekeeping. Popular attractions Planters Barn Theater and Bluff City Theater ...
9/10 Wonderful! (160 reviews)
"The proprietor met us at the door and helped us carry our baggage to our room. He provided us with a continental breakfast which included homemade bread. Everywhere we wanted to go was walkable with a great restaurant just across the street. My wife and I enjoyed staying there and will do so again ..."

Reviewed on Dec 2, 2023

Main Street Bed & Breakfast
Lighthouse Hospitality Hannibal
Lighthouse Hospitality Hannibal
2.5 out of 5
111 Bird St, Hannibal, MO
  • 2 min walk from Mark Twain Boyhood Home and Museum
The price is $200 per night from Jan 8 to Jan 9
$200
per night
Jan 8 - Jan 9
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.2/10 Wonderful! (86 reviews)
"This is our second time staying and we love it. I love the jetted tub after walking around Hannibal and going to the Christmas events. There was a lot going on around town, so we toured the boyhood home of Mark Twain, did some Christmas shopping, went out to eat and had drinks. It's a nice walkable ..."

Reviewed on Dec 4, 2023

Lighthouse Hospitality Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Hannibal

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Hannibal.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Hannibal’s 126 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $48. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Hannibal hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Hannibal. No matter your reason for visiting Hannibal, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Hannibal hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Hannibal for as low as $48.

How many hotels are there in Hannibal?

With over 126 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $48.

How to find cheap car rentals in Hannibal?

Finding a cheap car rental deal in Hannibal is as easy as scoring cheap hotels in Hannibal. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Hannibal now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Hannibal right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.