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Hotels in Northeast Florida

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Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
  • 6 min drive from Mayo Clinic Florida
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (4,019 reviews)
"Ok"

Reviewed on Jun 3, 2026

Margaritaville Jacksonville Beach
Guy Harvey Resort on St Augustine Beach

Guy Harvey Resort on St Augustine Beach

3 out of 5
860 A1A Beach Blvd St. Augustine FL
  • 1 hour drive from Mayo Clinic Florida
Book a stay at this beach hotel in St. Augustine. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
8.8/10 Excellent! (3,076 reviews)
"The front staff and the bartender/waitstaff were so friendly and helpful! I was there celebrating my birthday, and I will def will come back when I visit FL again! Great vibe and great stay!"

Reviewed on Jun 3, 2026

Guy Harvey Resort on St Augustine Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
  • 19 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,633 reviews)
"Excellent experience in every way 10/10"

Reviewed on Jun 3, 2026

Hyatt Regency Jacksonville
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road Jacksonville FL
  • 11 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast ...
8.4/10 Very Good! (1,419 reviews)
"The room itself is very outdated. Bedroom wall bubbled up due to the water damage from the bathroom."

Reviewed on Jun 3, 2026

Embassy Suites by Hilton Jacksonville Baymeadows
Amelia Hotel at the Beach

Amelia Hotel at the Beach

2.5 out of 5
1997 S Fletcher Ave Fernandina Beach FL
  • 1 hour drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Fernandina Beach. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and ...
8.6/10 Excellent! (2,161 reviews)
"Right at the beach."

Reviewed on Jun 3, 2026

Amelia Hotel at the Beach
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
  • 10 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (1,895 reviews)
"Wyndham Gardens has become my go to Jacksonville hotel for short trips and I have enjoyed the hotel. This location has been perfect for our 1-2 nights stays for concerts and shows. Only a 15 minute drive to the stadium and plenty of restaurants and attractions. The staff has always been friendly ..."

Reviewed on Jun 2, 2026

Wyndham Garden Jacksonville
Hyatt Place St. Augustine/Vilano Beach

Hyatt Place St. Augustine/Vilano Beach

3 out of 5
117 Vilano Road St. Augustine FL
  • 58 min drive from Mayo Clinic Florida
Stay at this hotel in St. Augustine. Enjoy free breakfast, free WiFi, and a free beach shuttle. Our guests praise the breakfast and the helpful staff in our ...
9.2/10 Wonderful! (1,361 reviews)
"Clean and well located"

Reviewed on Jun 2, 2026

Hyatt Place St. Augustine/Vilano Beach
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
1515 1st St N Jacksonville Beach FL
  • 7 min drive from Mayo Clinic Florida
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free breakfast, 2 outdoor pools, and a beach locale. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,669 reviews)
"Great staff giant room on short notice with ocean view. The pool was amazing and so big. We had a blast!!"

Reviewed on Jun 3, 2026

Hampton Inn Jacksonville Beach/Oceanfront
Villa 1565

Villa 1565

3 out of 5
137 San Marco Ave St. Augustine FL
  • 1 hour drive from Mayo Clinic Florida
Stay at this hotel in St. Augustine. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (2,040 reviews)
"2nd room met our expectations!"

Reviewed on Jun 3, 2026

Villa 1565
Weekly Inn

Weekly Inn

2 out of 5
8016 Arlington Expressway Service Rd Jacksonville FL
  • 14 min drive from Mayo Clinic Florida
Stay at this motel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our ...
7.6/10 Good! (1,305 reviews)
"Communication barrier due to foreign workers. Was there 4 three days with my baby and was given hand towels for bath towels stating they were out. It was a great price for a twin room. Clean-no bugs. Bad water pressure. Front desk was hard to deal with. Overall good stay for the money. Need ENGLISH ..."

Reviewed on Jun 3, 2026

Weekly Inn
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
  • 46 min drive from Mayo Clinic Florida
Book a stay at this beach vacation home in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in ...
8.4/10 Very Good! (1,212 reviews)
"We loved the trails and easy access to restaurants and shopping. The room was a little dated, and the shuttle was unreliable, but overall, it was a great trip. The grounds were immaculate and the service was spot on."

Reviewed on Jun 2, 2026

The Villas of Amelia Island
Quality Inn St Augustine Historic District Area

Quality Inn St Augustine Historic District Area

3 out of 5
2800 N. Ponce de Leon Blvd St. Augustine FL
  • 58 min drive from Mayo Clinic Florida
Book a stay at this business-friendly motel in St. Augustine. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the ...
8.6/10 Excellent! (2,091 reviews)
"The location is convenient to everything in Saint Augustine and Saint Augustine Beach. The staff was very professional. Breakfast was OK, not great, but OK. It seems all hotels are serving those fluorescent yellow reconstituted scrambled eggs. YUCK! I did have yogurt and hot coffee."

Reviewed on Jun 3, 2026

Quality Inn St Augustine Historic District Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Northeast Florida

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Frequently Asked Questions About Northeast Florida hotels

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How many hotels are there in Northeast Florida?

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