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Choose from 583 Mazeppa Hotel Deals
Kahler Grand Hotel
Clean, quiet, wonderful front desk staff, close to Mayo.
Reviewed on Feb 8, 2026
Aspen Suites
Everybody was polite. Morning breakfast was similar to other places I have stayed. In the afternoon they have light foods that were also complimentary. Hallways are tight coming off elevator.
Reviewed on Feb 8, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Front desk and cleaning staff are so kind and helpful! Rooms are clean and up to date! Comfortable beds and atmosphere! Definitely stay again.
Reviewed on Jan 31, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Could use more staff in hotel. Rooms were ok. Shuttle to Mayo was a little crowded at times.
Reviewed on Feb 3, 2026
Hyatt House Rochester/Mayo Clinic Area
Clean, comfortable. Most of the staff were very kind and accommodating. One particular evening front desk person was very unprofessional and rude. Overall, good stay.
Reviewed on Feb 6, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
clean, great customer service, when asked for towels and toilet paper got them fast, no noise complaints
Reviewed on Feb 2, 2026
Kahler Inn and Suites - Mayo Clinic Area
The room was comfortable, the bedding, nice. The hotel was quiet at night, but there's massive construction going on in every direction, from which the noise starts at 7:30am. Every hotel in the area would be the same for noise. Breakfast was good except the pancakes were tough like shoe leather, ...
Reviewed on Feb 6, 2026
Hampton Inn Rochester-South
Very friendly staff always willing to help. Great breakfast area with evening soup which was wonderful on these cold January nights. Housekeeping did not come one time during our stay and the front desk was accommodating to give us extra towels and supplies we needed for our room.
Reviewed on Feb 3, 2026
Spark by Hilton Rochester South
Room was very clean, staff was excellent in every way
Reviewed on Feb 7, 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Staff was very friendly, facilities were clean, nice breakfast area, pool area was clean. Room was very nice and large. We had no issues and will stay again at our next Mayo visit!
Reviewed on Jan 30, 2026
Brentwood Inn & Suites
Clean
Reviewed on Jan 27, 2026
St James Hotel, a Historic Hotel of America
Alyssa, the front desk staff, was outstanding. She went above and beyond to make sure our stay was comfortable. We love the St. James Hotel for a weekend getaway!
Reviewed on Feb 1, 2026
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