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Hotels in Southwest Coast Florida

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Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy, Sarasota, FL
  • 20 min drive from Siesta Key Beach
Stay at this 3-star business-friendly hotel in Sarasota. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (4,596 reviews)
The breakfast was amazing

Reviewed on Nov 8, 2025

Kompose Boutique Hotel
Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

4 out of 5
5500 Sunseeker Way, 785, Punta Gorda, FL
  • 1 hour drive from Siesta Key Beach
Stay at this 4-star spa resort in Punta Gorda. Enjoy 2 outdoor pools, a full-service spa, and 7 restaurants. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,600 reviews)
Clean room friendly staff

Reviewed on Nov 6, 2025

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 4-star beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,619 reviews)
Great staff and clean and comfortable room.

Reviewed on Nov 11, 2025

Margaritaville Beach Resort Fort Myers
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4.5-star luxury resort in Naples. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,910 reviews)
Great staff and beautiful hotel.

Reviewed on Nov 10, 2025

Naples Grande Beach Resort
Hilton Marco Island Beach Resort and Spa

Hilton Marco Island Beach Resort and Spa

4 out of 5
560 S Collier Blvd, Marco Island, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4-star beach resort in Marco Island. Enjoy a full-service spa, a beach locale, and room service. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (1,641 reviews)
Pool, beach, staff, room, amenities, location, everything was perfect!

Reviewed on Nov 3, 2025

Hilton Marco Island Beach Resort and Spa
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 3.5-star beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ...
8.8/10 Excellent! (1,016 reviews)
Great beachfront location with gorgeous view from balcony. Staff very friendly and always available. As a non-smoker, it was unpleasant to sit on balcony and smell cigarette smoke

Reviewed on Nov 10, 2025

Lani Kai Beachfront Resort
Spark by Hilton Sarasota Siesta Key Gateway

Spark by Hilton Sarasota Siesta Key Gateway

3 out of 5
6600 S Tamiami Trl, Sarasota, FL
  • 25 min walk from Siesta Key Beach
Stay at this 3-star business-friendly hotel in Sarasota. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (1,819 reviews)
Clean, friendly staff, bed was actually pretty comfortable for a hotel bed.

Reviewed on Nov 7, 2025

Spark by Hilton Sarasota Siesta Key Gateway
The Westin Sarasota

The Westin Sarasota

4 out of 5
100 Marina View Drive, Sarasota, FL
  • 12 min drive from Siesta Key Beach
Stay at this 4-star spa hotel in Sarasota. Enjoy a full-service spa, 2 restaurants, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,127 reviews)
Stunning view on the rooftop

Reviewed on Nov 8, 2025

The Westin Sarasota
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E, Cape Coral, FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Room was clean beds comfortable central location. Very good!

Reviewed on Nov 10, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive, Bonita Springs, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 4-star golf aparthotel in Bonita Springs. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Coconut Point Mall and Bonita ...
9/10 Wonderful! (700 reviews)
Rooms were super nice. Pools were amazing, the guys at the restaurant on site were all amazing but needed more than 2 people working and we waited a little while just to order take out.All in all a great weekend getaway.

Reviewed on Nov 9, 2025

Hyatt Vacation Club at Coconut Cove, Bonita Springs
Carlisle Inn

Carlisle Inn

3.5 out of 5
3727 Bahia Vista, Sarasota, FL
  • 11 min drive from Siesta Key Beach
Stay at this 3.5-star hotel in Sarasota. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.8/10 Exceptional! (2,078 reviews)
This hotel has been a favorite for our Florida trip, and we plan to become regulars when we visit my parents. Breakfast is exceptional, as is the cleanliness, housekeeping, and staff. Our only comment is that the beds were a bit soft for our tastes (lower back issues), but everything was comfortable ...

Reviewed on Nov 7, 2025

Carlisle Inn
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 3-star beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9/10 Wonderful! (1,399 reviews)
We were upgraded to a suite which was very clean and spacious. Unfortunately the bed was not very. comfortable, but the location and amenities more than made up for this one negative aspect and we would happily return to this resort.

Reviewed on Nov 9, 2025

Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southwest Coast Florida

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southwest Coast Florida.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southwest Coast Florida’s 45,467 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $98. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southwest Coast Florida hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southwest Coast Florida. No matter your reason for visiting Southwest Coast Florida, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southwest Coast Florida hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southwest Coast Florida for as low as $98.

How many hotels are there in Southwest Coast Florida?

With over 45,467 hotels in Southwest Coast Florida, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $98.

How to find cheap car rentals in Southwest Coast Florida?

Finding a cheap car rental deal in Southwest Coast Florida is as easy as scoring cheap hotels in Southwest Coast Florida. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.