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Hotels in Southwest Coast Florida

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Choose from 44160 Southwest Coast Florida Hotel Deals

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy, Sarasota, FL
  • 20 min drive from Siesta Key Beach
Stay at this 3-star business-friendly hotel in Sarasota. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
9/10 Wonderful! (4,341 reviews)
"Everything was excellent. I definitely will return. I do have allergies to dander and even with how clean everything was I ended up with really bad allergies. Take allergy meds if you have my same problem. I was a bit humiliated when I approached the breakfast buffet to check it out prior to deciding ..."

Reviewed on Sep 9, 2025

Kompose Boutique Hotel
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4.5-star luxury resort in Naples. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,757 reviews)
"Love it."

Reviewed on Sep 9, 2025

Naples Grande Beach Resort
Inn on Fifth

Inn on Fifth

4 out of 5
699 5th Ave S, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4-star spa hotel in Naples. Enjoy a full-service spa, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,003 reviews)
"Staff was very friendly and helpful. Pool was clean with bar and hot tub. Nice gym. Located right in the heart of old Naples. They have shuttle to the beach and offer chairs and umbrellas."

Reviewed on Sep 10, 2025

Inn on Fifth
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 4-star beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,457 reviews)
"Relax place"

Reviewed on Sep 10, 2025

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 3.5-star beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ...
8.6/10 Excellent! (1,019 reviews)
"The room was very clean and beautiful balcony view of the ocean. The staff were very friendly. There was a pretty dining room were we had a good breakfast. I wish they would had offered a small token (maybe a free drink or appetizer) when we let them know we were celebrating our anniversary. The ..."

Reviewed on Sep 9, 2025

Lani Kai Beachfront Resort
Sunseeker Resort Charlotte Harbor

Sunseeker Resort Charlotte Harbor

4.5 out of 5
5500 Sunseeker Way, 785, Punta Gorda, FL
  • 1 hour drive from Siesta Key Beach
Stay at this 4.5-star luxury resort in Punta Gorda. Enjoy 2 outdoor pools, a full-service spa, and 7 restaurants. Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,470 reviews)
"Great resort! Will definitely come back."

Reviewed on Sep 12, 2025

Sunseeker Resort Charlotte Harbor
Hilton Marco Island Beach Resort and Spa

Hilton Marco Island Beach Resort and Spa

4 out of 5
560 S Collier Blvd, Marco Island, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4-star beach resort in Marco Island. Enjoy a full-service spa, a beach locale, and room service. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (1,550 reviews)
"Love the hotel"

Reviewed on Sep 11, 2025

Hilton Marco Island Beach Resort and Spa
Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound

4 out of 5
12324 Manatee Avenue West, Bradenton, FL
  • 41 min drive from Siesta Key Beach
Stay at this 4-star hotel in Bradenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,710 reviews)
"The place is especial"

Reviewed on Sep 8, 2025

Compass Hotel by Margaritaville Anna Maria Sound
Carlisle Inn

Carlisle Inn

3.5 out of 5
3727 Bahia Vista, Sarasota, FL
  • 11 min drive from Siesta Key Beach
Stay at this 3.5-star hotel in Sarasota. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.8/10 Exceptional! (2,008 reviews)
Awesome Place to stay.
"This is the best place I have ever stayed, cleanest, friendliest, and nicest place we have ever stayed, I have stayed here before, and love it and will stay here every time that I stay in Sarasota in the future if they have any rooms available."

Reviewed on Sep 8, 2025

Carlisle Inn
Hyatt House Naples/5th Avenue

Hyatt House Naples/5th Avenue

3.5 out of 5
1345 5th Avenue South, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 3.5-star business-friendly hotel in Naples. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,444 reviews)
"Súper limpio y acogedor"

Reviewed on Sep 8, 2025

Hyatt House Naples/5th Avenue
The Westin Sarasota

The Westin Sarasota

4 out of 5
100 Marina View Drive, Sarasota, FL
  • 12 min drive from Siesta Key Beach
Stay at this 4-star spa hotel in Sarasota. Enjoy a full-service spa, 2 restaurants, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,072 reviews)
"$50 per valet without other option is too high"

Reviewed on Sep 8, 2025

The Westin Sarasota
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E, Cape Coral, FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Pool! 5/5"

Reviewed on Sep 11, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southwest Coast Florida

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southwest Coast Florida.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southwest Coast Florida’s 44,160 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $81. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southwest Coast Florida hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southwest Coast Florida. No matter your reason for visiting Southwest Coast Florida, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southwest Coast Florida hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southwest Coast Florida for as low as $81.

How many hotels are there in Southwest Coast Florida?

With over 44,160 hotels in Southwest Coast Florida, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $81.

How to find cheap car rentals in Southwest Coast Florida?

Finding a cheap car rental deal in Southwest Coast Florida is as easy as scoring cheap hotels in Southwest Coast Florida. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.