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Hotels in Southwest Coast Florida

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Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy Sarasota FL
  • 20 min drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Sarasota. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (4,661 reviews)
Staff was great! Room clean! Food and drink was tasty 😊

Reviewed on Nov 21, 2025

Kompose Boutique Hotel
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,658 reviews)
Very clean and friendly resort

Reviewed on Nov 23, 2025

Margaritaville Beach Resort Fort Myers
Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

4 out of 5
5500 Sunseeker Way Punta Gorda FL
  • 1 hour drive from Siesta Key Beach
Book a stay at this spa resort in Punta Gorda. Enjoy 2 outdoor pools, a full-service spa, and 7 restaurants. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,626 reviews)
The team at work that I booked this for loved this hotel!

Reviewed on Nov 20, 2025

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive Naples FL
  • 3 hours drive from Siesta Key Beach
Book a stay at this luxury resort in Naples. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,927 reviews)
THE STAFF AND ROOMS WERE GREAT. THE LOCATION IS CLOSE TO EVERYTHING AND ENJOYED THE FOOD AND DRINKS AT THE BAR EXCELLENT CHOICE OF BOURBONS

Reviewed on Nov 21, 2025

Naples Grande Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ...
8.8/10 Excellent! (1,020 reviews)
Great and clean room. The front desk people were very nice friendly and helpful the restaurant was good and the coffee shop and the beach maintenance was superb.

Reviewed on Nov 21, 2025

Lani Kai Beachfront Resort
Carlisle Inn

Carlisle Inn

3.5 out of 5
3727 Bahia Vista Sarasota FL
  • 11 min drive from Siesta Key Beach
Stay at this hotel in Sarasota. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.8/10 Exceptional! (2,097 reviews)
Beautiful, clean and smelled amazing! Also free cookies in the evening!

Reviewed on Nov 19, 2025

Carlisle Inn
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive Bonita Springs FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this golf aparthotel in Bonita Springs. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Coconut Point Mall and Bonita ...
9/10 Wonderful! (706 reviews)
Property was lovely. View of the golf course from the balcony was nice!

Reviewed on Nov 19, 2025

Hyatt Vacation Club at Coconut Cove, Bonita Springs
Golden Host Resort - Sarasota

Golden Host Resort - Sarasota

3 out of 5
4675 N Tamiami Trl Sarasota FL
  • 18 min drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Sarasota. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (2,151 reviews)
Not sure what the negatives reviewers experienced but my husband & I had a wonderful stay. From the delightful & friendly woman at check-in to the clean & quiet room at a very reasonable rate. I always enjoy staying in place that also have charm and the Golden Host Resort had that too - a cool vintage ...

Reviewed on Nov 22, 2025

Golden Host Resort - Sarasota
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9/10 Wonderful! (1,422 reviews)
Room 129 has some wall damage between the toilet and shower. Also under the toilet tank (l had something fall back there) looked like it was leftover construction debris and dust. When l first went in the room l found a peanut M&M on the floor. It’s busy season. Maids are probably pushed to their ...

Reviewed on Nov 21, 2025

Sanibel Island Beach Resort
Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound

4 out of 5
12324 Manatee Avenue West Bradenton FL
  • 41 min drive from Siesta Key Beach
Stay at this hotel in Bradenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,850 reviews)
The hotel was very clean. The breakfast was excellent. The location of the hotel is very close to beaches and the hotel has great views to the marina.

Reviewed on Nov 19, 2025

Compass Hotel by Margaritaville Anna Maria Sound
Hilton Marco Island Beach Resort and Spa

Hilton Marco Island Beach Resort and Spa

4 out of 5
560 S Collier Blvd Marco Island FL
  • 3 hours drive from Siesta Key Beach
Book a stay at this beach resort in Marco Island. Enjoy a full-service spa, a beach locale, and room service. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (1,654 reviews)
Great place all around

Reviewed on Nov 23, 2025

Hilton Marco Island Beach Resort and Spa
La Quinta Inn & Suites by Wyndham Naples Downtown

La Quinta Inn & Suites by Wyndham Naples Downtown

2.5 out of 5
1555 5th Ave S Naples FL
  • 3 hours drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Naples. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,752 reviews)
Check in was seamless and the room was clean!

Reviewed on Nov 22, 2025

La Quinta Inn & Suites by Wyndham Naples Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southwest Coast Florida

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southwest Coast Florida.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southwest Coast Florida’s 45,744 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $84. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southwest Coast Florida hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southwest Coast Florida. No matter your reason for visiting Southwest Coast Florida, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southwest Coast Florida hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southwest Coast Florida for as low as $84.

How many hotels are there in Southwest Coast Florida?

With over 45,744 hotels in Southwest Coast Florida, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $84.

How to find cheap car rentals in Southwest Coast Florida?

Finding a cheap car rental deal in Southwest Coast Florida is as easy as scoring cheap hotels in Southwest Coast Florida. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.