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Hotels in Clayton Station

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Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 5 min drive from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,077 reviews)
Room comfortable and clean. Dtaff very polite, professional, and helpful.

Reviewed on Jan 25, 2026

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Clayton Plaza Hotel & Extended Stay
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
  • 6 min drive from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,054 reviews)
Clean room and great staff

Reviewed on Jan 27, 2026

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Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
  • 5 min drive from St. Louis Zoo
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (556 reviews)
Very courteo

Reviewed on Jan 13, 2026

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The Ritz-Carlton, St. Louis
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
  • 29 min walk from St. Louis Zoo
Book a stay at this boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ...
9/10 Wonderful! (1,918 reviews)
Very friendly staff. Tony was a superb concierge!

Reviewed on Jan 30, 2026

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Moonrise Hotel
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE St. Louis MO
  • 26 min walk from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (699 reviews)
Always stay here! Great Staff and when we got stuck in the snow they all came to help !!!!!10/10!!!

Reviewed on Jan 28, 2026

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AC Hotel St. Louis Central West End
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

3 out of 5
828 N New Ballas Rd St. Louis MO
  • 16 min drive from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,000 reviews)
Spacious and clean room with very comfortable beds!

Reviewed on Jan 28, 2026

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Courtyard by Marriott St Louis Creve Coeur
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
  • 24 min walk from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,333 reviews)
The staff was nice and welcoming.

Reviewed on Jan 28, 2026

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Forest Park Hotel by MDR
Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park

2.5 out of 5
5650 Oakland Avenue St. Louis MO
  • 11 min walk from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
Great location

Reviewed on Jan 22, 2026

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Hampton Inn & Suites St. Louis at Forest Park
St. Louis Airport Hotel

St. Louis Airport Hotel

3.5 out of 5
9600 Natural Bridge Road St. Louis MO
  • 16 min drive from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
7.4/10 Good! (1,004 reviews)
Friendly staff and comfortable beds, but watch the parking! The rooms are clean and the bed was great, though the walls could use some new paint. My main issue was the parking lot—the spaces near the door are very narrow, and my new car ended up with $1,500 in damage from a door ding. Also, keep ...

Reviewed on Jan 31, 2026

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St. Louis Airport Hotel
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
  • 24 min walk from St. Louis Zoo
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in ...
9/10 Wonderful! (1,000 reviews)
The room was amazing and the staff made our stay perfect! There is so much to do at the hotel from the movie theatre to dining and drinks you really don’t have to leave.

Reviewed on Jan 23, 2026

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The Royal Sonesta Chase Park Plaza St. Louis
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
  • 4 min drive from St. Louis Zoo
Stay at this hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions St. Louis Union Station and Gateway ...
8.4/10 Very Good! (422 reviews)
The room was clean. Nothing fancy. Very small but felt cozy.

Reviewed on Jan 23, 2026

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The West End
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
  • 17 min drive from St. Louis Zoo
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,068 reviews)
All was OK

Reviewed on Jan 25, 2026

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Renaissance St. Louis Airport Hotel
See all 745 properties in Clayton Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.