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Choose from 385 Wytheville Hotel Deals

Sleep Inn Wytheville I-77 and I-81

Sleep Inn Wytheville I-77 and I-81

2.5 out of 5
135 Nye Cir Wytheville VA
  • 12 min walk from Wytheville Meeting Center
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,963 reviews)
"Breakfast was fresh and good room was nice and clean staff were friendly and helpful"

Reviewed on May 20, 2026

Sleep Inn Wytheville I-77 and I-81
Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

2.5 out of 5
955 Peppers Ferry Rd Wytheville VA
  • 7 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (1,570 reviews)
"Hotel is under renovation and it appears hotel is renting to long term customers (90% empty). TV didn't work, no satellite connection. No soap in bathroom sink. Skimpy breakfast - only dried cereal & some fruit, pancake machine."

Reviewed on May 19, 2026

Ramada by Wyndham Wytheville
Spark by Hilton Wytheville Holston Rd I 81

Spark by Hilton Wytheville Holston Rd I 81

2.5 out of 5
315 Holston Rd Wytheville VA
  • 26 min walk from Wytheville Meeting Center
Stay at this hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (218 reviews)
"Easy on and off from highway, clean and comfortable."

Reviewed on May 17, 2026

Spark by Hilton Wytheville Holston Rd I 81
Tru by Hilton Wytheville

Tru by Hilton Wytheville

2.5 out of 5
245 Boyd Ave Wytheville VA
  • 9 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
"Everything was great for a quick trip."

Reviewed on May 20, 2026

Tru by Hilton Wytheville
Spark by Hilton Wytheville East Main Street

Spark by Hilton Wytheville East Main Street

2.5 out of 5
2015 East Main Street Wytheville VA
  • 22 min walk from Wytheville Meeting Center
Stay at this hotel in Wytheville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wohlfahrt Haus Dinner Theatre and Mountainview ...
8.8/10 Excellent! (133 reviews)
"Basically a little roadside hotel, fine for what it is"

Reviewed on May 16, 2026

Spark by Hilton Wytheville East Main Street
Red Roof Inn Wytheville

Red Roof Inn Wytheville

3 out of 5
220 Lithia Rd Wytheville VA
  • 21 min walk from Wytheville Meeting Center
Stay at this motel in Wytheville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wohlfahrt Haus Dinner Theatre and Mountainview ...
8.4/10 Very Good! (381 reviews)
"Good overnight stay."

Reviewed on May 20, 2026

Red Roof Inn Wytheville
Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville

2 out of 5
140 Lithia Rd Wytheville VA
  • 20 min walk from Wytheville Meeting Center
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,221 reviews)
"The pancake machine had issues. Room was clean. Staff was responsive. Breakfast was ok. Parking was good."

Reviewed on May 19, 2026

Travelodge by Wyndham Wytheville
Quality Inn & Suites

Quality Inn & Suites

2 out of 5
1900 E Main St Wytheville VA
  • 19 min walk from Wytheville Meeting Center
Stay at this hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Wohlfahrt ...
7.8/10 Good! (149 reviews)
"Nothing!"

Reviewed on May 18, 2026

Quality Inn & Suites
The Bolling Wilson Hotel

The Bolling Wilson Hotel

3 out of 5
170 East Main Street Wytheville VA
  • 17 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
9.6/10 Exceptional! (874 reviews)
"It’s an amazing building with a lot of history. The staff was very polite and helpful."

Reviewed on May 20, 2026

The Bolling Wilson Hotel
Comfort Suites Wytheville near Conference Center

Comfort Suites Wytheville near Conference Center

2.5 out of 5
695 Peppers Ferry Rd Wytheville VA
  • 4 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,001 reviews)
"Room was extremely nice and clean. The breakfast had lots of choices and met our expectations. I would definitely stay here again!"

Reviewed on May 19, 2026

Comfort Suites Wytheville near Conference Center
Days Inn by Wyndham Wytheville

Days Inn by Wyndham Wytheville

2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73 Wytheville VA
  • 25 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,002 reviews)
"The room and bed were clean and comfortable."

Reviewed on May 20, 2026

Days Inn by Wyndham Wytheville
Garner Hotel Wytheville East by IHG

Garner Hotel Wytheville East by IHG

3 out of 5
1800 East Main Street Wytheville VA
  • 21 min walk from Wytheville Meeting Center
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,001 reviews)
"Clean room nice beds"

Reviewed on May 17, 2026

Garner Hotel Wytheville East by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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