Search Cheap Flights to
Wytheville

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Wytheville Flights as Low as $226

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Wed, Aug 20 - Sun, Aug 31
BUF
Buffalo Niagara Intl.
ROA
Roanoke Regional
$226 Roundtrip, just found
$226
Roundtrip
just found
Select Delta flight, departing Wed, Aug 20 from Buffalo Niagara Intl. to Roanoke Regional, returning Sun, Aug 31, priced at $226 just found
American Airlines
Wed, Sep 10 - Sat, Sep 13
ALB
Albany Intl.
ROA
Roanoke Regional
$229 Roundtrip, found 13 hours ago
$229
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Sep 10 from Albany Intl. to Roanoke Regional, returning Sat, Sep 13, priced at $229 found 13 hours ago
American Airlines
Tue, Jul 29 - Tue, Aug 5
IAH
George Bush Intercontinental
TRI
Tri-Cities Regional
$235 Roundtrip, found 1 hour ago
$235
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Jul 29 from George Bush Intercontinental to Tri-Cities Regional, returning Tue, Aug 5, priced at $235 found 1 hour ago
Delta
Tue, Jul 1 - Fri, Jul 4
DAL
Love Field
ROA
Roanoke Regional
$241 Roundtrip, found 19 hours ago
$241
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Jul 1 from Love Field to Roanoke Regional, returning Fri, Jul 4, priced at $241 found 19 hours ago
Bargain Flight
Sat, Oct 4 - Tue, Oct 7
SAT
San Antonio Intl.
ROA
Roanoke Regional
$241 Roundtrip, just found
$241
Roundtrip
just found
Select Bargain Flight flight, departing Sat, Oct 4 from San Antonio Intl. to Roanoke Regional, returning Tue, Oct 7, priced at $241 just found
Delta
Tue, Jul 15 - Thu, Jul 24
TUL
Tulsa Intl.
ROA
Roanoke Regional
$249 Roundtrip, found 22 hours ago
$249
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Jul 15 from Tulsa Intl. to Roanoke Regional, returning Thu, Jul 24, priced at $249 found 22 hours ago
Delta
Tue, Jul 15 - Wed, Jul 23
ORD
O'Hare Intl.
ROA
Roanoke Regional
$263 Roundtrip, found 22 hours ago
$263
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Jul 15 from O'Hare Intl. to Roanoke Regional, returning Wed, Jul 23, priced at $263 found 22 hours ago
American Airlines
Thu, Jul 17 - Tue, Jul 22
IAH
George Bush Intercontinental
ROA
Roanoke Regional
$263 Roundtrip, found 9 hours ago
$263
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Thu, Jul 17 from George Bush Intercontinental to Roanoke Regional, returning Tue, Jul 22, priced at $263 found 9 hours ago
Bargain Flight
Tue, Sep 16 - Tue, Sep 23
LGA
LaGuardia
ROA
Roanoke Regional
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Sep 16 from LaGuardia to Roanoke Regional, returning Tue, Sep 23, priced at $267 found 1 day ago
United
Thu, Jul 17 - Mon, Jul 21
ORD
O'Hare Intl.
ROA
Roanoke Regional
$285 Roundtrip, found 22 hours ago
$285
Roundtrip
found 22 hours ago
Select United flight, departing Thu, Jul 17 from O'Hare Intl. to Roanoke Regional, returning Mon, Jul 21, priced at $285 found 22 hours ago
American Airlines
Thu, Aug 14 - Mon, Aug 18
PHX
Sky Harbor Intl.
ROA
Roanoke Regional
$294 Roundtrip, found 3 hours ago
$294
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Aug 14 from Sky Harbor Intl. to Roanoke Regional, returning Mon, Aug 18, priced at $294 found 3 hours ago
American Airlines
Wed, Sep 10 - Sat, Sep 13
BUF
Buffalo Niagara Intl.
TRI
Tri-Cities Regional
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 10 from Buffalo Niagara Intl. to Tri-Cities Regional, returning Sat, Sep 13, priced at $297 found 2 days ago
Delta
Tue, Oct 14 - Tue, Oct 21
LGA
LaGuardia
TRI
Tri-Cities Regional
$347 Roundtrip, found 14 hours ago
$347
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Oct 14 from LaGuardia to Tri-Cities Regional, returning Tue, Oct 21, priced at $347 found 14 hours ago
Delta
Tue, Sep 9 - Wed, Sep 10
PHX
Sky Harbor Intl.
TRI
Tri-Cities Regional
$349 Roundtrip, found 11 hours ago
$349
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Sep 9 from Sky Harbor Intl. to Tri-Cities Regional, returning Wed, Sep 10, priced at $349 found 11 hours ago
Bargain Flight
Thu, Jul 3 - Tue, Jul 8
SEA
Seattle - Tacoma Intl.
ROA
Roanoke Regional
$356 Roundtrip, found 22 hours ago
$356
Roundtrip
found 22 hours ago
Select Bargain Flight flight, departing Thu, Jul 3 from Seattle - Tacoma Intl. to Roanoke Regional, returning Tue, Jul 8, priced at $356 found 22 hours ago
Delta
Tue, Sep 16 - Tue, Sep 23
DAL
Love Field
TRI
Tri-Cities Regional
$365 Roundtrip, found 1 day ago
$365
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 16 from Love Field to Tri-Cities Regional, returning Tue, Sep 23, priced at $365 found 1 day ago

Cheap Flights to Wytheville

Fall in love at first flight with your vacation to Wytheville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Wytheville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Wytheville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Wytheville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Wytheville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the ROA airport.

What is the cheapest month to fly to Wytheville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Wytheville are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Wytheville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Wytheville.

What airport is best to fly into Wytheville?

When you’re planning your trip to Wytheville, convenience is the name of the game. Luckily, Wytheville Virginia Highlands Airport is nearby so you can deplane and get going on checking off everything on your Wytheville must-do list.

How much are flights to Wytheville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Wytheville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $226, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Wytheville?

The trick to saving a stack of cash on your flight to Wytheville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $226 right now, why wait?

Wytheville Flight Information
Destination airport
Tri-Cities Regional
Destination airport IATA code
TRI
Roundtrip price
$223

Last Minute Hotel Deals in Wytheville

Ramada by Wyndham Wytheville
Ramada by Wyndham Wytheville
2.5 out of 5
955 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (1,257 reviews)
"They were very accommodating we asked for a room near easy parking and by the pool, when we got into the room we walked in and it smelled terribly bad like cigarette smoke asked the front desk to move us to a different room. No problem. The morning breakfast is nothing to write home about. But the ..."

Reviewed on Jun 23, 2025

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Ramada by Wyndham Wytheville
Days Inn by Wyndham Wytheville
Days Inn by Wyndham Wytheville
2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,009 reviews)
"Room was ok. Bed was pretty good, but bathroom was old and dimly lit in the shower. Some good restaurants within walking distance."

Reviewed on Jun 22, 2025

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Days Inn by Wyndham Wytheville
Sleep Inn Wytheville I-77 and I-81
Sleep Inn Wytheville I-77 and I-81
2.5 out of 5
135 Nye Cir, Wytheville, VA
Stay at this hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,588 reviews)
"Very comfortable stay. Stayed on our way to the Smokies and on the way back."

Reviewed on Jun 23, 2025

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Sleep Inn Wytheville I-77 and I-81
Travelodge by Wyndham Wytheville
Travelodge by Wyndham Wytheville
2 out of 5
140 Lithia Rd, Wytheville, VA
Book a stay at this business-friendly motel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,332 reviews)
"Nice, clean room"

Reviewed on Jun 22, 2025

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Travelodge by Wyndham Wytheville
Country Inn & Suites by Radisson, Wytheville, VA
Country Inn & Suites by Radisson, Wytheville, VA
3 out of 5
697 Peppers Ferry Road, Wytheville, VA
Stay at this 3-star business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,005 reviews)
"Parking was convenient. It was clean. There was an indoor pool and a hot tub"

Reviewed on Jun 23, 2025

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Country Inn & Suites by Radisson, Wytheville, VA
Comfort Suites Wytheville
Comfort Suites Wytheville
2.5 out of 5
695 Peppers Ferry Rd, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.6/10 Excellent! (1,005 reviews)
"Overall was a great experience. The hot tub being broken was our only let down. Staff was very friendly and plenty of food to eat at breakfast."

Reviewed on Jun 20, 2025

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Comfort Suites Wytheville
Super 8 by Wyndham Wytheville
Super 8 by Wyndham Wytheville
2 out of 5
130 Nye Circle, I-77 exit 41, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,009 reviews)
"👍"

Reviewed on Jun 20, 2025

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Super 8 by Wyndham Wytheville
Holiday Inn Express and Suites Wytheville by IHG
Holiday Inn Express and Suites Wytheville by IHG
2.5 out of 5
165 Malin Dr, Wytheville, VA
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,004 reviews)
"Kids had fun at the pool"

Reviewed on Jun 23, 2025

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Holiday Inn Express and Suites Wytheville by IHG
See all 366 properties in Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.