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Hotels in Southeast Minnesota

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Tonight May 22 - May 23Next weekend May 27 - May 29

Last Minute Hot Rate® Hotel Deals in Southeast Minnesota

We Hide Hotel Names So You Can Find 4-Star Hotels At 2-Star Prices. Choose the Location, Star Rating & Amenities. Let Hotwire Find You the Best Deal. Book Today!

Choose from 612 Southeast Minnesota Hotel Deals

Med City Hotel & Suites
Med City Hotel & Suites
2.5 out of 5
4141 Maine Avenue SE, Rochester, MN, 55904
  • 10 min drive from Mayo Clinic
The price is $69 per night from Jun 8 to Jun 9
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the clean rooms in our reviews. ...
Med City Hotel & Suites
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN, 55904
  • 11 min drive from Mayo Clinic
The price is $94 per night from May 29 to May 30
Stay at this 3-star family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Express Suites Riverport Inn & Suites
Express Suites Riverport Inn & Suites
3 out of 5
900 Bruski Dr, Winona, MN, 55987
  • 2 hours drive from Mayo Clinic
The price is $120 per night from May 23 to May 24
Stay at this 3-star business-friendly hotel in Winona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Express Suites Riverport Inn & Suites
Even Hotel Rochester - Mayo Clinic Area
Even Hotel Rochester - Mayo Clinic Area
3.5 out of 5
101 11TH AVENUE SW, SUITE A, Rochester, MN, 55902
  • 17 min walk from Mayo Clinic
The price is $101 per night from May 30 to May 31
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a restaurant, and breakfast. Popular attractions Mayo Civic Center and Soldiers ...
Even Hotel Rochester - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area
3.5 out of 5
220 S Broadway, Rochester, MN, 55904
  • 6 min walk from Mayo Clinic
The price is $110 per night from May 28 to May 29
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast. Our guests praise the restaurant and the clean ...
Hotel Indigo Rochester – Mayo Clinic Area
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN, 55902
  • 2 min walk from Mayo Clinic
The price is $135 per night from Jun 3 to Jun 4
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the restaurant and the helpful staff ...
Kahler Grand Hotel
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
110 Civic Center Drive NW, Rochester, MN, 55901
  • 7 min walk from Mayo Clinic
The price is $110 per night from May 23 to May 24
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Popular attractions Mayo Civic Center and ...
Hyatt House Rochester/Mayo Clinic Area
Hampton Inn Rochester
Hampton Inn Rochester
2.5 out of 5
1755 S Broadway, Rochester, MN, 55904
  • 4 min drive from Mayo Clinic
The price is $100 per night from Jun 5 to Jun 6
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hampton Inn Rochester
Country Inn & Suites by Radisson, Albert Lea, MN
Country Inn & Suites by Radisson, Albert Lea, MN
2.5 out of 5
2214 E Main St, Albert Lea, MN, 56007
  • 3 hours drive from Mayo Clinic
The price is $101 per night from May 25 to May 26
Stay at this business-friendly hotel in Albert Lea. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Country Inn & Suites by Radisson, Albert Lea, MN
Microtel Inn & Suites by Wyndham Rochester South Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester South Mayo Clinic
3 out of 5
4165 Maine Ave SE, Rochester, MN, 55904
  • 10 min drive from Mayo Clinic
The price is $72 per night from May 25 to May 26
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
Microtel Inn & Suites by Wyndham Rochester South Mayo Clinic
Ramada by Wyndham Albert Lea
Ramada by Wyndham Albert Lea
3 out of 5
2301 E Main St, Albert Lea, MN, 56007
  • 3 hours drive from Mayo Clinic
The price is $72 per night from May 23 to May 24
Stay at this 3-star business-friendly hotel in Albert Lea. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Ramada by Wyndham Albert Lea
St James Hotel, a Historic Hotel of America
St James Hotel, a Historic Hotel of America
3.5 out of 5
406 Main St., Red Wing, MN, 55066
  • 2 hours drive from Mayo Clinic
The price is $138 per night from May 25 to May 26
Stay at this 3.5-star spa hotel in Red Wing. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the restaurant and the helpful staff in ...
St James Hotel, a Historic Hotel of America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southeast Minnesota

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southeast Minnesota hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southeast Minnesota.

Choosing the right hotel in Minnesota has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southeast Minnesota’s 612 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southeast Minnesota hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeast Minnesota. No matter your reason for visiting Southeast Minnesota, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeast Minnesota hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southeast Minnesota for as low as $69.

How many hotels are there in Southeast Minnesota?

With over 612 hotels in Southeast Minnesota, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Southeast Minnesota?

Finding a cheap car rental deal in Southeast Minnesota is as easy as scoring cheap hotels in Southeast Minnesota. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southeast Minnesota now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southeast Minnesota right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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