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Hotels in Florida Keys

Choose from 8285 Florida Keys Hotel Deals

Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,322 reviews)
"All good !!!!!!!!!!!!!!!"

Reviewed on Jun 8, 2026

Cheeca Lodge & Spa
Reefhouse Resort & Marina

Reefhouse Resort & Marina

4.5 out of 5
103800 Overseas Hwy Key Largo FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this luxury hotel in Key Largo. Enjoy free parking, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
9.4/10 Exceptional! (1,476 reviews)
"Very good"

Reviewed on Jun 7, 2026

Reefhouse Resort & Marina
Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this beach hotel in Islamorada. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the pool in our reviews. ...
9.2/10 Wonderful! (1,746 reviews)
"A beautiful place to stay on the Florida Keys! The staff were all so nice, breakfast was good, and the views were unbeatable. We would definitely consider returning!"

Reviewed on Jun 7, 2026

Chesapeake Beach Resort
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
  • 2 hours drive from Florida Keys Beaches
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,012 reviews)
"It was ok"

Reviewed on Jun 7, 2026

Hawks Cay Resort
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

5 out of 5
1 Knights Key Boulevard Marathon FL
  • 1 hour drive from Florida Keys Beaches
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
9.2/10 Wonderful! (1,180 reviews)
"Nuestra experiencia fue excelente. El hotel está muy limpio, las instalaciones son hermosas y bien cuidadas. El personal fue amable y atento en todo momento, haciéndonos sentir como en casa. Disfrutamos mucho de la piscina, las áreas comunes y la tranquilidad del lugar. Sin duda volveríamos y lo ..."

Reviewed on Jun 9, 2026

Isla Bella Beach Resort & Spa
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
  • 3 hours drive from Florida Keys Beaches
Stay at this hotel in Key Largo. Enjoy free WiFi, a marina, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,385 reviews)
"Nice location. Great staff."

Reviewed on Jun 9, 2026

Waterside Suites & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this beach resort in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,082 reviews)
"Amo este hotel . Es espectacular"

Reviewed on Jun 8, 2026

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
  • 2 hours drive from Florida Keys Beaches
Book a stay at this beach resort in Long Key. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,307 reviews)
"Great resort! Will be back!!!"

Reviewed on Jun 8, 2026

Lime Tree Bay Resort
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this beach hotel in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,040 reviews)
"Great place to stay will come back again has many amenities that other resorts change extra for"

Reviewed on Jun 8, 2026

Islander Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
  • 2 hours drive from Florida Keys Beaches
Book a stay at this beach resort in Islamorada. Enjoy 2 restaurants, a private beach, and 3 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,300 reviews)
"Although this is priced at a high end resort, there is nothing high end about it. Needs a lot of updating. Our room was very much in need of some deep cleaning and updating. We stayed on the 5th floor which smelled of pot the whole stay. Housekeeping was ok but very inconsistent. There is absolutely ..."

Reviewed on Jun 9, 2026

Amara Cay Resort
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy Key Largo FL
  • 3 hours drive from Florida Keys Beaches
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,758 reviews)
"Great place to stay!"

Reviewed on Jun 8, 2026

Bayside Inn Key Largo
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

3 out of 5
13201 Overseas Hwy Marathon FL
  • 1 hour drive from Florida Keys Beaches
Book a stay at this business-friendly hotel in Marathon. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the restaurant ...
9.2/10 Wonderful! (1,155 reviews)
"Nos encanto el hotel, muy comodo y con todo lo que necesitas para pasar una linda estadia en Marathon, tiene dos restaurantes cerca y muchas opciones de entretenimiento."

Reviewed on Jun 8, 2026

Fairfield Inn & Suites by Marriott Marathon Florida Keys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florida Keys

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $179. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florida Keys hotel deals at the last minute.

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Frequently Asked Questions About Florida Keys hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Florida Keys?

With over 8,285 hotels in Florida Keys, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $179.

How to find cheap car rentals in Florida Keys?

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