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Hotels in Florida Keys

Choose from 8122 Florida Keys Hotel Deals

Chesapeake Beach Resort
Chesapeake Beach Resort
3.5 out of 5
83409 Overseas Hwy, Islamorada, FL
  • 3 hours drive from Duval Street
Stay at this 3.5-star beach hotel in Islamorada. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,479 reviews)
"Super nice staff! Great place to stay!"

Reviewed on Jul 2, 2025

Chesapeake Beach Resort
Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
5 out of 5
1 Knights Key Boulevard, MM 47, Marathon, FL
  • 2 hours drive from Duval Street
Stay at this 5-star luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,006 reviews)
"Wonderful"

Reviewed on Jul 5, 2025

Isla Bella Beach Resort & Spa
Cheeca Lodge & Spa
Cheeca Lodge & Spa
5 out of 5
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
  • 3 hours drive from Duval Street
Stay at this 5-star luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,113 reviews)
"Amazing, we will be back as soon as possible. Luxury vacation!"

Reviewed on Jul 4, 2025

Cheeca Lodge & Spa
Hampton Inn Key Largo Manatee Bay
Hampton Inn Key Largo Manatee Bay
2.5 out of 5
102400 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
Book a stay at this beach hotel in Key Largo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,001 reviews)
"This is a great property with its own small beach, a tiki bar and a nice pool. Good breakfast included. Spacious rooms with outside seating area. Would recommend a stay here."

Reviewed on Jul 4, 2025

Hampton Inn Key Largo Manatee Bay
Hawks Cay Resort
Hawks Cay Resort
4 out of 5
61 Hawks Cay Blvd, Marathon, FL
  • 2 hours drive from Duval Street
Book a stay at this beach hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8/10 Very Good! (1,002 reviews)
Our stay at the Hawks Cay Reaort
"It was our first stay at this hotel. The room was comfortable and an ample space. We loved that the flooring has been replaced with imitation of wood. The shower very nice and separated with a door from the toilet area. The ceiling fan needs to be clean, we noticed it was dirty. From what other family ..."

Reviewed on Jul 4, 2025

Hawks Cay Resort
Amara Cay Resort
Amara Cay Resort
4 out of 5
80001 Overseas Hwy, Islamorada, FL
  • 3 hours drive from Duval Street
Stay at this 4-star beach resort in Islamorada. Enjoy 2 restaurants, a private beach, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (1,220 reviews)
"Place was clean and the amenities are really nice. This is our third time in this hotel and we missed the store to buy essentials and souvenirs and we missed also the ice creams options, the ice cream fridge was empty."

Reviewed on Jun 30, 2025

Amara Cay Resort
Islander Resort
Islander Resort
4 out of 5
82100 Overseas Highway, Islamorada, FL
  • 3 hours drive from Duval Street
Stay at this 4-star beach hotel in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Everything is as described. Great environment and beautiful staying places."

Reviewed on Jul 3, 2025

Islander Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Baker's Cay Resort Key Largo, Curio Collection by Hilton
4 out of 5
97000 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
Book a stay at this beach resort in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,001 reviews)
"The property is great for families"

Reviewed on Jun 30, 2025

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Fairfield Inn & Suites by Marriott Marathon Florida Keys
Fairfield Inn & Suites by Marriott Marathon Florida Keys
2.5 out of 5
13201 Overseas Hwy, Marathon, FL
  • 2 hours drive from Duval Street
Book a stay at this business-friendly hotel in Marathon. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (1,005 reviews)
"love i"

Reviewed on Jul 3, 2025

Fairfield Inn & Suites by Marriott Marathon Florida Keys
Bayside Inn Key Largo
Bayside Inn Key Largo
3 out of 5
99490 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
Stay at this 3-star beach hotel in Key Largo. Enjoy free WiFi, a private beach, and a 24-hour fitness center. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (1,528 reviews)
"good"

Reviewed on Jul 6, 2025

Bayside Inn Key Largo
Reefhouse Resort & Marina
Reefhouse Resort & Marina
3.5 out of 5
103800 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
Stay at this 3.5-star beach hotel in Key Largo. Enjoy free parking, a full-service spa, and 3 restaurants. Our guests praise the pool and the bar in our reviews. ...
9.2/10 Wonderful! (1,306 reviews)
"We had a great time and loved the hotel!"

Reviewed on Jul 1, 2025

Reefhouse Resort & Marina
Playa Largo Resort & Spa, Autograph Collection
Playa Largo Resort & Spa, Autograph Collection
4.5 out of 5
97450 Overseas Highway, Key Largo, FL
  • 4 hours drive from Duval Street
Stay at this 4.5-star luxury resort in Key Largo. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,003 reviews)
"Great set up. Pool, beach and bar are all convenient. Go out for meals. Only complaint was that they seem short on cleaning staff."

Reviewed on Jul 2, 2025

Playa Largo Resort & Spa, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florida Keys

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $137. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florida Keys hotel deals at the last minute.

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Frequently Asked Questions About Florida Keys hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Florida Keys?

With over 8,122 hotels in Florida Keys, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $137.

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