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Hotels in Southeast Illinois

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Choose from 973 Southeast Illinois Hotel Deals

Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
  • 4 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,016 reviews)
"Clean and quiet. Very convenient to eateries."

Reviewed on Oct 12, 2025

Best Western Delta Inn
Comfort Suites Mattoon East

Comfort Suites Mattoon East

2.5 out of 5
1408 Broadway Ave E, Mattoon, IL
  • 5 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (829 reviews)
"The room was clean and the AC/heat worked perfectly."

Reviewed on Oct 12, 2025

Comfort Suites Mattoon East
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street, Metropolis, IL
  • 1 hour drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,009 reviews)
"Everything was clean and comfortable. Beds were great and so was the breakfast. Would definitely recommend for a quick stay."

Reviewed on Oct 13, 2025

Holiday Inn Express Metropolis by IHG
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

2.5 out of 5
1200 N Raney, Effingham, IL
  • 4 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,005 reviews)
"Clean room"

Reviewed on Oct 11, 2025

Country Inn & Suites by Radisson, Effingham, IL
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

2.5 out of 5
2118 E 5th St, Metropolis, IL
  • 1 hour drive from Shawnee National Forest
Stay at this hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,008 reviews)
"Basic place and was fine for the night. The bed was comfy, shower clean and warm. Breakfast a bit lacking and property overall worn but fine for a night."

Reviewed on Oct 12, 2025

Quality Inn & Suites Metropolis I-24
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America, Effingham, IL
  • 4 hours drive from Shawnee National Forest
Stay at this 3-star business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
"Convenient baby sleeping option, clean and warm pool"

Reviewed on Oct 12, 2025

La Quinta Inn & Suites by Wyndham Effingham
Economy Inn & Suites

Economy Inn & Suites

2 out of 5
411 E Poplar St, Harrisburg, IL
  • 36 min drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Harrisburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Harrisburg Township Park District ...
8/10 Very Good! (86 reviews)
"Staff Were Very Helpful and Pleasant. Accommodating. Great Job."

Reviewed on Oct 8, 2025

Economy Inn & Suites
Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey

2 out of 5
933 N Route 49, Casey, IL
  • 5 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Casey. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (800 reviews)
"Nice place, quiet, clean, and I would stay there again."

Reviewed on Oct 11, 2025

Days Inn & Suites by Wyndham Casey
Unique Suites Hotel

Unique Suites Hotel

2.5 out of 5
920 W Lincoln Ave, Charleston, IL
  • 5 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (696 reviews)
"Check in was a little strange but otherwise a good stay"

Reviewed on Oct 12, 2025

Unique Suites Hotel
Terre Haute Casino Resort

Terre Haute Casino Resort

4 out of 5
4500 East Margaret Drive, Terre Haute, IN
  • 5 hours drive from Shawnee National Forest
Stay at this 4-star business-friendly resort in Terre Haute. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Terre Haute Casino Resort ...
9.2/10 Wonderful! (593 reviews)
"Check in is so late - other than that enjoyed our stay"

Reviewed on Oct 12, 2025

Terre Haute Casino Resort
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
  • 2 hours drive from Shawnee National Forest
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,483 reviews)
"Great motel at great price"

Reviewed on Oct 11, 2025

Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites Terre Haute

Drury Inn & Suites Terre Haute

3 out of 5
3040 HWY 41 S, Terre Haute, IN
  • 5 hours drive from Shawnee National Forest
Stay at this 3-star business-friendly hotel in Terre Haute. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
"Love the "Kick back the day" perk!!"

Reviewed on Oct 10, 2025

Drury Inn & Suites Terre Haute
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southeast Illinois

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southeast Illinois.

Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southeast Illinois’s 973 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southeast Illinois hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeast Illinois. No matter your reason for visiting Southeast Illinois, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeast Illinois hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southeast Illinois for as low as $64.

How many hotels are there in Southeast Illinois?

With over 973 hotels in Southeast Illinois, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Southeast Illinois?

Finding a cheap car rental deal in Southeast Illinois is as easy as scoring cheap hotels in Southeast Illinois. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.