Search Cheap Flights to
Southeast Illinois

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Southeast Illinois Flights as Low as $213

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Breeze Airways
Breeze Airways
Contour Airlines
Breeze Airways
Contour Airlines
Delta
Contour Airlines
Contour Airlines
Contour Airlines
Contour Airlines
Contour Airlines
Breeze Airways
American Airlines
Delta
American Airlines

Cheap Flights to Southeast Illinois

Fall in love at first flight with your vacation to Southeast Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Southeast Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Illinois are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southeast Illinois.

What airport is best to fly into Southeast Illinois?

When you’re planning your trip to Southeast Illinois, convenience is the name of the game. Luckily, Southeast Illinois Evansville Regional Airport is nearby so you can deplane and get going on checking off everything on your Southeast Illinois must-do list.

How much are flights to Southeast Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $213, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Illinois?

The trick to saving a stack of cash on your flight to Southeast Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $213 right now, why wait?

Southeast Illinois Flight Information
Destination airport
Barkley Regional
Destination airport IATA code
PAH
Roundtrip price
$325

Last Minute Hotel Deals in Southeast Illinois

Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

2.5 out of 5
2118 E 5th St Metropolis IL
Stay at this hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,002 reviews)
Pool was closed for maintenance. Breakfast was great. Lots of choices. Room was decent. Looked to be needing a little vacuuming. Room had a smell. Not a bad smell but can't pinpoint what exactly it was. Bought some air freshener sprayed it around several times a day. Staff was polite and helpful. ...

Reviewed on Apr 26, 2026

Quality Inn & Suites Metropolis I-24
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street Metropolis IL
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Great breakfast! Delicious and so many options for all my picky kids. Friendly staff!

Reviewed on Apr 29, 2026

Holiday Inn Express Metropolis by IHG
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

2.5 out of 5
1811 W Fayette Avenue Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
Very clean. Beds were very comfortable. However, it was loud and we woke up several times to others in the building banging, slamming doors. I also received an attitude of annoyance when I checked in. I wanted to use Apple Pay as my family and I were traveling and I don’t carry all cards on me while ...

Reviewed on Apr 27, 2026

Baymont by Wyndham Effingham
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

3 out of 5
1606 W Fayette Avenue Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,006 reviews)
Yes,everything looked & tasted great, nice variety of menu items..

Reviewed on Apr 26, 2026

Ramada by Wyndham Effingham
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

2.5 out of 5
1200 N Raney Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,005 reviews)
The AC and fan did not work in the room. It was just not that clean. I mean ok enough for stay over. But would not use it again.

Reviewed on Apr 29, 2026

Country Inn & Suites by Radisson, Effingham, IL
Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,001 reviews)
Was a very nice hotel

Reviewed on Apr 29, 2026

Best Western Delta Inn
Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG

2.5 out of 5
1604 West Fayette Avenue Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
Clean room, quick check in. Our room was very quiet. We left early am so didn’t utilize the free breakfast.

Reviewed on Apr 27, 2026

Holiday Inn Express & Suites Effingham by IHG
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America Effingham IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
Clean and affordable. Hot breakfast. Good coffee. No complaints.

Reviewed on Apr 30, 2026

La Quinta Inn & Suites by Wyndham Effingham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.