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Southeast Illinois

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Cheap Flights to Southeast Illinois

Fall in love at first flight with your vacation to Southeast Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Southeast Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Illinois are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Southeast Illinois.

What airport is best to fly into Southeast Illinois?

When you’re planning your trip to Southeast Illinois, convenience is the name of the game. Luckily, Southeast Illinois Evansville Regional Airport is nearby so you can deplane and get going on checking off everything on your Southeast Illinois must-do list.

How much are flights to Southeast Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Illinois?

The trick to saving a stack of cash on your flight to Southeast Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Southeast Illinois Flight Information
Destination airport
Southeast Illinois
Destination airport IATA code
MDH

Last Minute Hotel Deals in Southeast Illinois

Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr, Located right off of I-57/70, Effingham, IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,030 reviews)
"This property is right off the interstate, which is always a benefit for a one night stay. Front desk was professional, personable and informative. The room was clean and comfortable. The air conditioner was fairly quiet which was great. I would stay here again."

Reviewed on Sep 29, 2025

Best Western Delta Inn
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

2.5 out of 5
1200 N Raney, Effingham, IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,002 reviews)
"Very nice property. Close to a lot of restaurants and I70. The young lady at the front desk was very polite and helpful."

Reviewed on Oct 2, 2025

Country Inn & Suites by Radisson, Effingham, IL
Unique Suites Hotel

Unique Suites Hotel

2.5 out of 5
920 W Lincoln Ave, Charleston, IL
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (687 reviews)
"our room was clean but no added amenities. would stay again though!"

Reviewed on Sep 29, 2025

Unique Suites Hotel
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

2.5 out of 5
2179 East 5th Street, Metropolis, IL
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,002 reviews)
Comfy and cleab
"Comfortable, clean room. Pet friendly. Great hot cinnamon buns for breakfast!"

Reviewed on Oct 3, 2025

Holiday Inn Express Metropolis by IHG
Comfort Suites Mattoon East

Comfort Suites Mattoon East

2.5 out of 5
1408 Broadway Ave E, Mattoon, IL
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (820 reviews)
"I was pleasantly surprised by this hotel. My room was clean and comfortable. The check in process was efficient and easy. The hotel is close to many casual dining options. There were several hot options for breakfast. Overall great value for the room rate. I will not hesitate to stay here again when ..."

Reviewed on Sep 24, 2025

Comfort Suites Mattoon East
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3 out of 5
1103 Avenue Of Mid America, Effingham, IL
Stay at this 3-star business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,019 reviews)
"New and clean"

Reviewed on Sep 30, 2025

La Quinta Inn & Suites by Wyndham Effingham
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

2.5 out of 5
2118 E 5th St, Metropolis, IL
Stay at this hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,002 reviews)
Basic place to stop
"Basic accomodations. Location needs some sprucing up. Breakfast is basic as well. Waffles, toast, yogurt; no meats. Room AC slightly loud but working."

Reviewed on Oct 5, 2025

Quality Inn & Suites Metropolis I-24
Economy Inn & Suites

Economy Inn & Suites

2 out of 5
411 E Poplar St, Harrisburg, IL
Book a stay at this business-friendly hotel in Harrisburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Harrisburg Township Park District ...
8/10 Very Good! (82 reviews)
"Room very clean big tv very pleasant check in"

Reviewed on Sep 30, 2025

Economy Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.