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Choose from 101 Charleston Hotel Deals
Super 8 by Wyndham Charleston/Sikeston East MO
"The outside of the hotel needs some work The breakfast needed more than instant oatmeal for breakfast. Muffins wrapped separately would have been nice. Banana along with the apples. Cold cereals in little bowls. Just anything more than what they had."
Reviewed on Jun 11, 2026
The Riverstone Hotel Charleston-Sikeston
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
Reviewed on Jun 7, 2026
Eagle Inn Charleston
"Great"
Reviewed on Apr 14, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
"Best stay of our vacation."
Reviewed on Jun 15, 2026
Drury Inn & Suites Sikeston, MO
"This was a wonderful stay for the night while traveling. Thankful for the recommendation from the front desk to eat at Lamberts restaurant 3 minutes down the road. So fun!"
Reviewed on Jun 15, 2026
Candlewood Suites Cape Girardeau by IHG
"Overbooked my stay didn't have a room"
Reviewed on Jun 8, 2026
The Riverview
"Very nice!"
Reviewed on Jun 14, 2026
Days Inn and Suites by Wyndham Sikeston
"Lobby reeked like pot and cigarettes, room was not the cleanest and smelled like wet dog, water only got lukewarm, and milk for breakfast was days expired. Pics on Expedia definitely don’t look like the room we had."
Reviewed on Jun 8, 2026
Pear Tree Inn Cape Girardeau West
"Jane helped at check in, she was polite and very helpful. She informed me of the Drury rewards program and the amazing amenities on site. The facility was very nice and clean, well lit parking lot and hallways. We travel a lot and have to say it is definitely one of the best places we have stayed! ..."
Reviewed on Jun 15, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"Staff and breakfast were excellent."
Reviewed on Jun 14, 2026
Hampton Inn Sikeston
"."
Reviewed on Jun 15, 2026
Drury Inn & Suites Cape Girardeau
"Good"
Reviewed on Jun 15, 2026
Find cheap hotels in Charleston
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Charleston.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Charleston’s 101 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Charleston hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Charleston. No matter your reason for visiting Charleston, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Charleston hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Charleston?
With over 101 hotels in Charleston, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.
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