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Hotels in Berrys Crossroads

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Choose from 110 Berrys Crossroads Hotel Deals

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
  • 9 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,648 reviews)
Always a pleasant stay. It’s my go-to hotel when traveling from Florida to Maryland.

Reviewed on Apr 25, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 9 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,262 reviews)
The property is well maintained and the staff were super helpful and friendly. I will definitely stay on my next trip through the area.

Reviewed on Apr 26, 2026

Park Inn by Radisson Florence, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
  • 10 min walk from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,005 reviews)
Very pleasant and our dogs loved it too

Reviewed on Apr 26, 2026

Hyatt Place Florence Downtown
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
  • 9 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (81 reviews)
Excellent place to stay ,clean rooms and very respectful staff.

Reviewed on Apr 25, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
  • 10 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,005 reviews)
It was nice

Reviewed on Apr 24, 2026

Days Inn by Wyndham Florence/I-95 North
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 out of 5
1735 Stokes Road Florence SC
  • 9 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (899 reviews)
Veronica was at the front desk when we checked in. She is exactly the type of person you want to greet customers! She was genuine, had a great smile, and was warm and caring. Another employee was Lacy (I think that was her name). She was an older woman who was working the breakfast. She was so helpful, ...

Reviewed on Apr 24, 2026

Hampton Inn & Suites Florence-North-I-95
Sleep Inn Florence North

Sleep Inn Florence North

2.5 out of 5
1833 Florence Park Dr Florence SC
  • 10 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (715 reviews)
Needs updating

Reviewed on Apr 17, 2026

Sleep Inn Florence North
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
  • 9 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,601 reviews)
It was a wonderful experience I loved the way that the hotel was cleaness respectful staff a clean room

Reviewed on Apr 23, 2026

La Quinta Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr Florence SC
  • 10 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (1,000 reviews)
Parking was very good and well lit.

Reviewed on Apr 16, 2026

Microtel Inn & Suites by Wyndham Florence
Red Roof Inn Dillon, SC

Red Roof Inn Dillon, SC

2 out of 5
810 Radford Boulevard Dillon SC
  • 1 hour drive from Mcleod Regional Medical Center
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
6.2/10 (1,003 reviews)
Stayed at the red roof in me and my wife for the second time in a year and a 1 and this staff was great. The magnifies were great. The rooms were clean. The property overall was very well. Maintained, hi, I didn't smell marijuana, but a few times but it was at the gas station next door it's not legal ...

Reviewed on Apr 22, 2026

Red Roof Inn Dillon, SC
Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 out of 5
2120 West Lucas Street Florence SC
  • 10 min drive from Mcleod Regional Medical Center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
Great stop on a long drive, just off I95 so very convenient. Plenty of well lit parking which was great because we arrived quite late. The gentleman at the front desk was pleasant and quick to get us checked in (we were exhausted). Very clean, other guests were hanging out in the lobby and it was ...

Reviewed on Apr 17, 2026

Comfort Suites Florence I-95
Best Western Inn

Best Western Inn

2.5 out of 5
1808 W Lucas Street Florence SC
  • 8 min drive from Mcleod Regional Medical Center
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Dr. ...
7.8/10 Good! (1,000 reviews)
Staff was friendly. Rooms are pet friendly and relatively clean. Great water pressure In shower. Really great breakfast included.

Reviewed on Apr 19, 2026

Best Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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