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Sikeston Vacations

Pack those stellar shades. We have Sikeston vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Sikeston – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Sikeston vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Sikeston

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Sikeston vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Sikeston well.

Top Hotel Deals

See all 62 Properties in Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau
    2.5 out of 5.0
     
     

    Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

    Pear Tree Inn Cape Girardeau Near the Medical Center$70

    Pear Tree Inn Cape Girardeau Near the Medical Center$70
    Americas Best Value Inn & Suites Sikeston

    Americas Best Value Inn & Suites Sikeston

    220 S Interstate Dr, Miner
      2.0 out of 5.0
       
       

      Situated in a rural location, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic ...

      Americas Best Value Inn & Suites Sikeston$60

      Americas Best Value Inn & Suites Sikeston$60
      Best Western Plus Sikeston

      Best Western Plus Sikeston

      120 S Interstate Drive, Miner
        2.5 out of 5.0
         
         

        Situated in Miner, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic Site and Kentucky ...

        Best Western Plus Sikeston$85

        Best Western Plus Sikeston$85
        Drury Plaza Hotel Cape Girardeau Conference Center

        Drury Plaza Hotel Cape Girardeau Conference Center

        3351 Percy Drive, Cape Girardeau
          3.0 out of 5.0
           
           

          Situated in Cape Girardeau, this hotel is 2.2 mi (3.5 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

          Drury Plaza Hotel Cape Girardeau Conference Center$125

          Drury Plaza Hotel Cape Girardeau Conference Center$125
          Pear Tree Inn Cape Girardeau West

          Pear Tree Inn Cape Girardeau West

          103 Cape West Pkwy, Cape Girardeau
            2.5 out of 5.0
             
             

            Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

            Pear Tree Inn Cape Girardeau West$70

            Pear Tree Inn Cape Girardeau West$70
            Auburn Place Hotel And Suites

            Auburn Place Hotel And Suites

            3265 William St, Cape Girardeau
              2.5 out of 5.0
               
               

              Situated in Cape Girardeau, this hotel is 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

              Auburn Place Hotel And Suites$79

              Auburn Place Hotel And Suites$79
              Super 8 by Wyndham Charleston MO

              Super 8 by Wyndham Charleston MO

              310 S Story St, Charleston
                2.0 out of 5.0
                 
                 

                Located in the heart of Charleston, this motel is within 20 mi (32 km) of Fort Defiance, Central Park, and Sikeston Depot Museum. Boot Heel Golf Club and Ullin ...

                Super 8 by Wyndham Charleston MO$50

                Super 8 by Wyndham Charleston MO$50
                Quality Inn Charleston

                Quality Inn Charleston

                102 Drake St, Charleston
                  2.5 out of 5.0
                   
                   

                  Situated in Charleston, this hotel is within 16 mi (25 km) of Central Park, Fort Defiance, and Sikeston Depot Museum. Boot Heel Golf Club and Kentucky Bend are ...

                  Quality Inn Charleston$66

                  Quality Inn Charleston$66
                  Hampton Inn Cape Girardeau I 55 East

                  Hampton Inn Cape Girardeau I 55 East

                  207 S Mt Auburn Rd, Cape Girardeau
                    2.5 out of 5.0
                     
                     

                    Situated in Cape Girardeau, this hotel is 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

                    Hampton Inn Cape Girardeau I 55 East$101

                    Hampton Inn Cape Girardeau I 55 East$101
                    Town House Inn Cape Giradreau

                    Town House Inn Cape Giradreau

                    505 North Kingshighway Street, Cape Girardeau
                      2.5 out of 5.0
                       
                       

                      Situated in Cape Girardeau, this motel is within 3 mi (5 km) of Cape Splash Family Aquatic Center, Southeast Missouri State University, and Isle Casino Cape ...

                      Town House Inn Cape Giradreau$60

                      Town House Inn Cape Giradreau$60

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.