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Sikeston

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Sikeston Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Sep 8 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$120 Roundtrip, found 2 hours ago
$120
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Tue, Sep 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $120 found 2 hours ago
Frontier Airlines
Sun, Sep 6 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$125 Roundtrip, found 2 hours ago
$125
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $125 found 2 hours ago
Frontier Airlines
Sun, Sep 6 - Fri, Sep 11
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Fri, Sep 11, priced at $130 found 1 day ago
Frontier Airlines
Sat, Aug 8 - Tue, Aug 25
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$140 Roundtrip, found 6 days ago
$140
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sat, Aug 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $140 found 6 days ago
American Airlines
Tue, Sep 8 - Fri, Sep 11
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$165 Roundtrip, found 1 day ago
$165
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Fri, Sep 11, priced at $165 found 1 day ago
Frontier Airlines
Tue, Sep 8 - Fri, Sep 18
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$173 Roundtrip, found 1 day ago
$173
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Sep 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Fri, Sep 18, priced at $173 found 1 day ago
Frontier Airlines
Sun, Sep 6 - Fri, Sep 18
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$178 Roundtrip, found 1 day ago
$178
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Fri, Sep 18, priced at $178 found 1 day ago
Frontier Airlines
Wed, Sep 9 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 2 hours ago
$179
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Wed, Sep 9 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $179 found 2 hours ago
Frontier Airlines
Thu, Sep 10 - Sun, Sep 13
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$180 Roundtrip, found 2 hours ago
$180
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Thu, Sep 10 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Sep 13, priced at $180 found 2 hours ago
American Airlines
Tue, Sep 8 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$200 Roundtrip, found 2 hours ago
$200
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Sep 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $200 found 2 hours ago
United
Tue, Sep 8 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$220 Roundtrip, found 2 hours ago
$220
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Sep 8 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Sep 10, priced at $220 found 2 hours ago
Delta
Thu, Nov 26 - Tue, Dec 8
DAL
Love Field
STL
Lambert-St. Louis Intl.
$227 Roundtrip, found 2 hours ago
$227
Roundtrip
found 2 hours ago
Select Delta flight, departing Thu, Nov 26 from Love Field to Lambert-St. Louis Intl., returning Tue, Dec 8, priced at $227 found 2 hours ago
Bargain Flight
Thu, Aug 13 - Tue, Aug 25
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$268 Roundtrip, found 6 days ago
$268
Roundtrip
found 6 days ago
Select Bargain Flight flight, departing Thu, Aug 13 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $268 found 6 days ago
United
Wed, Sep 2 - Thu, Sep 10
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$304 Roundtrip, just found
$304
Roundtrip
just found
Select United flight, departing Wed, Sep 2 from Dallas-Fort Worth Intl. to Barkley Regional, returning Thu, Sep 10, priced at $304 just found
United
Fri, Jul 31 - Sat, Aug 1
BOS
Logan Intl.
PAH
Barkley Regional
$459 Roundtrip, found 1 day ago
$459
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 31 from Logan Intl. to Barkley Regional, returning Sat, Aug 1, priced at $459 found 1 day ago
Delta
Fri, Sep 4 - Sun, Sep 13
DAL
Love Field
PAH
Barkley Regional
$1,585 Roundtrip, found 10 hours ago
$1,585
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Sep 4 from Love Field to Barkley Regional, returning Sun, Sep 13, priced at $1,585 found 10 hours ago

Cheap Flights to Sikeston

Fall in love at first flight with your vacation to Sikeston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sikeston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sikeston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sikeston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sikeston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Sikeston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sikeston are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sikeston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Sikeston.

What airport is best to fly into Sikeston?

When you’re planning your trip to Sikeston, convenience is the name of the game. Luckily, Sikeston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Sikeston must-do list.

How much are flights to Sikeston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sikeston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sikeston?

The trick to saving a stack of cash on your flight to Sikeston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

Sikeston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$120

Last Minute Hotel Deals in Sikeston

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,007 reviews)
"Wonderful staff. Pet friendly"

Reviewed on Jul 24, 2026

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Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,003 reviews)
"Everything was well but the actual property was a little winding getting there (but i wasarriving at night) and there is not another business next to it, just a small lake, If you like that. Overall clean, nice and quiet. Nice breakfast room!"

Reviewed on Jul 25, 2026

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Best Western Plus Sikeston I-55
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,004 reviews)
"Poor location -- far from restaurants or grocery. The parking lot was dirty (cigarette butts, broken asphalt, weeds untrimmed). Stair rubber treads are broken (a customer easy to trip and fall). Shower floor was dirty. The room had stain couch fabric, a lamp broken, and the TV reception was poor. ..."

Reviewed on Jul 24, 2026

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Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (593 reviews)
"Fast checking in and out. Very friendly staff and abundant complimentary breakfast. Spacious room and we liked having a walk in shower. There was plenty of green space to walk our small dog. The only complaint we had is that when we sat on the sofa, the cushion covers came off. They did not zip securely ..."

Reviewed on Jul 19, 2026

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Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (484 reviews)
"Very clean and good breakfast"

Reviewed on Jul 25, 2026

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Holiday Inn Express & Suites Sikeston Southwest by IHG
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.4/10 Exceptional! (100 reviews)
"Friendly staff, great breakfast, nice amenities"

Reviewed on Jul 19, 2026

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Fairfield Inn & Suites by Marriott Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot Museum are located ...
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Super 8 by Wyndham Sikeston/Miner Area
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (802 reviews)
"N/a"

Reviewed on Jul 20, 2026

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Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
See all 319 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.