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Santee

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Santee Flights as Low as $154

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Thu, Oct 16 - Sun, Oct 19
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$154 Roundtrip, found 5 days ago
$154
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Thu, Oct 16 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Sun, Oct 19, priced at $154 found 5 days ago
American Airlines
Sat, Sep 13 - Sat, Sep 27
LGA
LaGuardia
CAE
Columbia Metropolitan
$157 Roundtrip, just found
$157
Roundtrip
just found
Select American Airlines flight, departing Sat, Sep 13 from LaGuardia to Columbia Metropolitan, returning Sat, Sep 27, priced at $157 just found
Delta
Wed, Sep 17 - Tue, Sep 23
LGA
LaGuardia
CAE
Columbia Metropolitan
$161 Roundtrip, found 4 days ago
$161
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Sep 17 from LaGuardia to Columbia Metropolitan, returning Tue, Sep 23, priced at $161 found 4 days ago
American Airlines
Sat, Aug 30 - Sun, Aug 31
DCA
Ronald Reagan Washington National
CAE
Columbia Metropolitan
$199 Roundtrip, found 1 day ago
$199
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 30 from Ronald Reagan Washington National to Columbia Metropolitan, returning Sun, Aug 31, priced at $199 found 1 day ago
United
Fri, Dec 19 - Wed, Dec 24
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$209 Roundtrip, just found
$209
Roundtrip
just found
Select United flight, departing Fri, Dec 19 from O'Hare Intl. to Columbia Metropolitan, returning Wed, Dec 24, priced at $209 just found
Delta
Mon, Jan 5 - Sat, Jan 10
IAH
George Bush Intercontinental
CAE
Columbia Metropolitan
$240 Roundtrip, found 9 hours ago
$240
Roundtrip
found 9 hours ago
Select Delta flight, departing Mon, Jan 5 from George Bush Intercontinental to Columbia Metropolitan, returning Sat, Jan 10, priced at $240 found 9 hours ago
Delta
Wed, Aug 20 - Sat, Aug 30
IAD
Washington Dulles Intl.
CAE
Columbia Metropolitan
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 20 from Washington Dulles Intl. to Columbia Metropolitan, returning Sat, Aug 30, priced at $246 found 1 day ago
Delta
Thu, Nov 27 - Tue, Dec 2
CVG
Cincinnati - Northern Kentucky Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 27 from Cincinnati - Northern Kentucky Intl. to Columbia Metropolitan, returning Tue, Dec 2, priced at $249 found 1 day ago
Delta
Wed, Oct 8 - Tue, Oct 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CAE
Columbia Metropolitan
$262 Roundtrip, found 3 days ago
$262
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Oct 8 from Baltimore Washington Intl. Thurgood Marshall to Columbia Metropolitan, returning Tue, Oct 14, priced at $262 found 3 days ago
Delta
Thu, Aug 28 - Wed, Sep 3
DTW
Detroit Metropolitan Wayne County
CAE
Columbia Metropolitan
$263 Roundtrip, found 19 hours ago
$263
Roundtrip
found 19 hours ago
Select Delta flight, departing Thu, Aug 28 from Detroit Metropolitan Wayne County to Columbia Metropolitan, returning Wed, Sep 3, priced at $263 found 19 hours ago
Delta
Mon, Aug 18 - Mon, Aug 25
ORF
Norfolk Intl.
CAE
Columbia Metropolitan
$277 Roundtrip, found 3 days ago
$277
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Aug 18 from Norfolk Intl. to Columbia Metropolitan, returning Mon, Aug 25, priced at $277 found 3 days ago
United
Sun, Oct 5 - Wed, Oct 8
SEA
Seattle - Tacoma Intl.
CAE
Columbia Metropolitan
$281 Roundtrip, found 20 hours ago
$281
Roundtrip
found 20 hours ago
Select United flight, departing Sun, Oct 5 from Seattle - Tacoma Intl. to Columbia Metropolitan, returning Wed, Oct 8, priced at $281 found 20 hours ago
United
Tue, Oct 14 - Wed, Oct 29
SMF
Sacramento Intl.
CAE
Columbia Metropolitan
$314 Roundtrip, found 2 days ago
$314
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 14 from Sacramento Intl. to Columbia Metropolitan, returning Wed, Oct 29, priced at $314 found 2 days ago
American Airlines
Thu, Aug 21 - Sun, Aug 24
HOU
William P. Hobby
CAE
Columbia Metropolitan
$317 Roundtrip, found 1 day ago
$317
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Aug 21 from William P. Hobby to Columbia Metropolitan, returning Sun, Aug 24, priced at $317 found 1 day ago
Delta
Sun, Aug 17 - Sat, Aug 23
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$369 Roundtrip, found 1 day ago
$369
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Aug 17 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Sat, Aug 23, priced at $369 found 1 day ago
American Airlines
Sat, Aug 30 - Sun, Aug 31
PDX
Portland Intl.
CAE
Columbia Metropolitan
$377 Roundtrip, found 1 day ago
$377
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 30 from Portland Intl. to Columbia Metropolitan, returning Sun, Aug 31, priced at $377 found 1 day ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $154, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $154 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$154

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,324 reviews)
Good room for the money
"The room was clean and handy to the freeway and restaurants. Comfortable enough. They need to fix the ice machine."

Reviewed on Aug 13, 2025

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Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (500 reviews)
"Friendly"

Reviewed on Aug 12, 2025

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Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,001 reviews)
Good
"The room and bathroom weren't very clean. The hotel needs to step up its pest control; we killed a cockroach that was on the ceiling. The minibar wasn't cooling properly. Otherwise, it was fine for a one-night stay."

Reviewed on Aug 4, 2025

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Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,001 reviews)
surprise in Santee
"Loved this hotel. The staff could not be friendlier and helpful. The room was immaculate, and the layout was unique and spacious. The water pressure was very good (I love a good shower) and the beds were quite comfortable. I did have an issue with the thermostat - it seemed to go on auto pilot in ..."

Reviewed on Aug 4, 2025

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Hampton Inn Santee-I-95
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (929 reviews)
"The staff were great from checking in to checking out. The room was very clean and well kept. Would highly recommend."

Reviewed on Aug 6, 2025

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Holiday Inn Santee by IHG
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
7.8/10 Good! (1,000 reviews)
"Clean with a good breakfast."

Reviewed on Aug 14, 2025

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Comfort Inn & Suites Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (647 reviews)
"Clean, comfortable, convenient stop on highway"

Reviewed on Jul 19, 2025

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Travelodge by Wyndham Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"Clean and comfortable. Just stayed the night while traveling on I95."

Reviewed on Aug 6, 2025

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Best Western Plus Santee Inn
See all 291 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.