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Santee Flights as Low as $204
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Cheap Flights to Santee
Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Santee
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the CAE airport.
What is the cheapest month to fly to Santee?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in March, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Santee?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Santee.
What airport is best to fly into Santee?
When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.
How much are flights to Santee?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $204, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Santee?
The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $204 right now, why wait?
Destination airport | Columbia Metropolitan |
|---|---|
Destination airport IATA code | CAE |
Roundtrip price | $204 |
Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Very friendly staff.
Reviewed on Jan 18, 2026

Tru By Hilton Santee
Very nice! Very friendly check in, great beds & shower, very clean. Easy to reach from I 95.
Reviewed on Jan 17, 2026

Hampton Inn Santee-I-95
The room is elegant
Reviewed on Jan 15, 2026

Comfort Inn & Suites Santee
The staff was excellent and the room was very clean. I would go there again.
Reviewed on Jan 23, 2026

Fairfield Inn & Suites by Marriott Santee
Safe parking clean rooms and excellent breakfast. Plus pet friendly as we have a 50 lb dog
Reviewed on Jan 13, 2026

Best Western Plus Santee Inn
yes
Reviewed on Jan 21, 2026

Holiday Inn Santee by IHG
Staff in the restaurant Dinner shift were excellent.
Reviewed on Jan 2, 2026

Quality Inn & Suites
Definitely in need of an upgrade. The room was very similar to rooms I have stayed at like a Motel 6 or Super 8. Trash was overflowing, ice machine didn’t work. The unit next to us - there was water flowing across the walkway from their wall air conditioner/heater unit.
Reviewed on Jan 11, 2026
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