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Santee

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Santee Flights as Low as $100

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Tue, Jul 22 - Tue, Jul 29
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$100 Roundtrip, just found
$100
Roundtrip
just found
Select Spirit Airlines flight, departing Tue, Jul 22 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Tue, Jul 29, priced at $100 just found
American Airlines
Tue, Sep 16 - Wed, Sep 24
LGA
LaGuardia
CAE
Columbia Metropolitan
$139 Roundtrip, found 3 hours ago
$139
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Sep 16 from LaGuardia to Columbia Metropolitan, returning Wed, Sep 24, priced at $139 found 3 hours ago
American Airlines
Sat, Aug 30 - Sun, Aug 31
DCA
Ronald Reagan Washington National
CAE
Columbia Metropolitan
$189 Roundtrip, found 13 hours ago
$189
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Aug 30 from Ronald Reagan Washington National to Columbia Metropolitan, returning Sun, Aug 31, priced at $189 found 13 hours ago
Spirit Airlines
Tue, Jul 8 - Sat, Jul 12
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$193 Roundtrip, found 5 hours ago
$193
Roundtrip
found 5 hours ago
Select Spirit Airlines flight, departing Tue, Jul 8 from Philadelphia Intl. to Columbia Metropolitan, returning Sat, Jul 12, priced at $193 found 5 hours ago
Bargain Flight
Wed, Oct 1 - Sat, Oct 4
BOS
Logan Intl.
CAE
Columbia Metropolitan
$205 Roundtrip, found 4 hours ago
$205
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Wed, Oct 1 from Logan Intl. to Columbia Metropolitan, returning Sat, Oct 4, priced at $205 found 4 hours ago
Delta
Tue, Aug 19 - Sun, Aug 24
RIC
Richmond Intl.
CAE
Columbia Metropolitan
$229 Roundtrip, found 10 hours ago
$229
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Aug 19 from Richmond Intl. to Columbia Metropolitan, returning Sun, Aug 24, priced at $229 found 10 hours ago
American Airlines
Tue, Aug 19 - Tue, Aug 26
CVG
Cincinnati - Northern Kentucky Intl.
CAE
Columbia Metropolitan
$229 Roundtrip, found 1 hour ago
$229
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Aug 19 from Cincinnati - Northern Kentucky Intl. to Columbia Metropolitan, returning Tue, Aug 26, priced at $229 found 1 hour ago
American Airlines
Wed, Aug 13 - Sun, Aug 17
BUF
Buffalo Niagara Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 14 hours ago
$249
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Aug 13 from Buffalo Niagara Intl. to Columbia Metropolitan, returning Sun, Aug 17, priced at $249 found 14 hours ago
Delta
Wed, Jul 9 - Tue, Jul 22
IAH
George Bush Intercontinental
CAE
Columbia Metropolitan
$253 Roundtrip, found 1 day ago
$253
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 9 from George Bush Intercontinental to Columbia Metropolitan, returning Tue, Jul 22, priced at $253 found 1 day ago
American Airlines
Fri, Jul 4 - Tue, Jul 8
SYR
Hancock Intl.
CAE
Columbia Metropolitan
$258 Roundtrip, found 13 hours ago
$258
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Jul 4 from Hancock Intl. to Columbia Metropolitan, returning Tue, Jul 8, priced at $258 found 13 hours ago
Delta
Sat, Aug 9 - Sun, Aug 10
MSP
Minneapolis - St. Paul Intl.
CAE
Columbia Metropolitan
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 9 from Minneapolis - St. Paul Intl. to Columbia Metropolitan, returning Sun, Aug 10, priced at $263 found 1 day ago
Delta
Wed, Jul 9 - Tue, Jul 15
SHV
Shreveport Regional
CAE
Columbia Metropolitan
$264 Roundtrip, found 6 hours ago
$264
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Jul 9 from Shreveport Regional to Columbia Metropolitan, returning Tue, Jul 15, priced at $264 found 6 hours ago
Delta
Sat, Aug 23 - Tue, Aug 26
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$273 Roundtrip, found 2 days ago
$273
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Aug 23 from John F. Kennedy Intl. to Columbia Metropolitan, returning Tue, Aug 26, priced at $273 found 2 days ago
Spirit Airlines
Thu, Jul 24 - Mon, Jul 28
DFW
Dallas-Fort Worth Intl.
CAE
Columbia Metropolitan
$273 Roundtrip, found 8 hours ago
$273
Roundtrip
found 8 hours ago
Select Spirit Airlines flight, departing Thu, Jul 24 from Dallas-Fort Worth Intl. to Columbia Metropolitan, returning Mon, Jul 28, priced at $273 found 8 hours ago
American Airlines
Tue, Jul 1 - Tue, Jul 8
DEN
Denver Intl.
CAE
Columbia Metropolitan
$274 Roundtrip, found 13 hours ago
$274
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jul 1 from Denver Intl. to Columbia Metropolitan, returning Tue, Jul 8, priced at $274 found 13 hours ago
Spirit Airlines
Wed, Jul 30 - Tue, Aug 5
PDX
Portland Intl.
CAE
Columbia Metropolitan
$278 Roundtrip, found 15 hours ago
$278
Roundtrip
found 15 hours ago
Select Spirit Airlines flight, departing Wed, Jul 30 from Portland Intl. to Columbia Metropolitan, returning Tue, Aug 5, priced at $278 found 15 hours ago

Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $100, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $100 right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$100

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,298 reviews)
"Not that great but its clean"

Reviewed on Jun 11, 2025

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Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (446 reviews)
"Absolutely amazing!!"

Reviewed on Jun 15, 2025

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Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,002 reviews)
"clean, friendly, functional….this is our favorite hotel to stay off 95 on the way to Florida…."

Reviewed on Jun 14, 2025

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Fairfield Inn & Suites by Marriott Santee
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (385 reviews)
"Clean n great owners"

Reviewed on Jun 14, 2025

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Quality Inn & Suites
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3 out of 5
139 Bradford Blvd, Santee, SC
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (894 reviews)
Include breakfast if you stay here as it is cheapr
"Nice place to stay when traveling 95. They have a restaurant with nobody in it. We had breakfast included but I had to go to the desk to find out where the waitress was. The breakfast was very good, but if you are looking for an early start this is not the place for you."

Reviewed on Jun 10, 2025

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Holiday Inn Santee by IHG
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
"Nice stay for overnight. Great pool!"

Reviewed on Jun 12, 2025

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Best Western Plus Santee Inn
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (996 reviews)
Convenient and Friendly Staff
"Conveniently located off I-95. The staff were all very friendly. The rooms were very spacious. The breakfast was great! The only downside was the beds need updated. They were very springy and uncomfortable. Overall good stay."

Reviewed on May 28, 2025

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Comfort Inn & Suites Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,002 reviews)
"Convenient off I95 easy off and easy on"

Reviewed on Jun 14, 2025

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Hampton Inn Santee-I-95
See all 279 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.