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Cheap Flights to Santee

Fall in love at first flight with your vacation to Santee by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santee on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santee, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santee

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santee with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to Santee?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santee are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santee?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Santee.

What airport is best to fly into Santee?

When you’re planning your trip to Santee, convenience is the name of the game. Luckily, Santee Charleston Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santee must-do list.

How much are flights to Santee?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santee on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santee?

The trick to saving a stack of cash on your flight to Santee? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Santee Flight Information
Destination airport
Columbia Metropolitan
Destination airport IATA code
CAE
Roundtrip price
$179

Last Minute Hotel Deals in Santee

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
The price is $89 per night from May 4 to May 5
$89
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,291 reviews)
"Good for an overnight stay."

Reviewed on Apr 28, 2025

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
The price is $122 per night from May 18 to May 19
$122
includes taxes & fees
May 18 - May 19
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (404 reviews)
"The property and staff were nice. The room was clean. Breakfast was okay."

Reviewed on Apr 26, 2025

Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
The price is $159 per night from May 11 to May 12
$159
includes taxes & fees
May 11 - May 12
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (1,003 reviews)
"Exceptional stay as usual. Best hotel on 95! Perfect place to stop when traveling from Virginia to Florida. Staff were all excellent. Kudos to Roz in the dining room. Very helpful and friendly. Would definitely recommend this hotel!"

Reviewed on Apr 30, 2025

Fairfield Inn & Suites by Marriott Santee
Holiday Inn Santee by IHG
Holiday Inn Santee by IHG
3 out of 5
139 Bradford Blvd, Santee, SC
The price is $145 per night from Jun 1 to Jun 2
$145
includes taxes & fees
Jun 1 - Jun 2
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Nice place to stay
"I had booked this hotel and discovered it was a tad beyond our turn off. However we were not disappointed! And it turned out it wasn’t that much out of our way. After traveling all day this looked like a newly built hotel. So the little newly added conveniences were appreciated. I kept thinking “ ..."

Reviewed on Apr 24, 2025

Holiday Inn Santee by IHG
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
The price is $151 per night from May 26 to May 27
$151
includes taxes & fees
May 26 - May 27
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,000 reviews)
"V good stay Comfortable beds and good with pet offering cookies and poop bags 2 free waters Would stay again"

Reviewed on Apr 29, 2025

Hampton Inn Santee-I-95
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
The price is $122 per night from May 11 to May 12
$122
includes taxes & fees
May 11 - May 12
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (983 reviews)
"Front desk was service was great! Lobby was comfortable and clean."

Reviewed on Apr 27, 2025

Comfort Inn & Suites Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
The price is $127 per night from May 11 to May 12
$127
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
"Nice older motel. Very well maintained. Comfy bed. Very friendly helpful staff. Only reason I didn’t give it a perfect score was the old stinky carpet in the room."

Reviewed on Apr 22, 2025

Best Western Plus Santee Inn
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
The price is $70 per night from May 7 to May 8
$70
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6/10 (361 reviews)
"…."

Reviewed on Apr 27, 2025

Quality Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.