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Featured Santee Hotels with a Pool
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Econo Lodge
9112 Old 6 Highway, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santee Cooper Country Club and Santee National Golf ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Super 8 by Wyndham Santee
9125 Old Highway 6, Santee, SC
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
Ramada by Wyndham Santee I-95
123 Mall Street, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Santee
Top Points of Interests in Santee
- Hotels near Santee State Park
- Hotels near Santee Cooper Country Club
- Hotels near Santee National Golf Club
- Hotels near Congaree National Park
- Hotels near Lake Marion
- Hotels near South Carolina State University
- Hotels near Edisto Memorial Gardens
- Hotels near Santee National Wildlife Refuge
- Hotels near Wyboo Golf Club
- Hotels near St. George United Methodist Church
- Hotels near St. George Country Club
- Hotels near I.P. Stanback Museum & Planetarium
Cities near Santee
- Orangeburg Hotels (21.85 mi)
- Sumter Hotels (30.87 mi)
- Coastal South Carolina Hotels (39.54 mi)
- Manning Hotels (20.95 mi)
- St. George Hotels (21.56 mi)
- Summerton Hotels (11.01 mi)
- Southeastern United States Hotels (212.28 mi)
- Eutawville Hotels (9.84 mi)
- The Carolinas Hotels (107.21 mi)
- Ridgeville Hotels (28.75 mi)
- Holly Hill Hotels (12.11 mi)
- Cross Hotels (21.9 mi)
- Saint Matthews Hotels (21.24 mi)
- Pineville Hotels (26.07 mi)
- Vance Hotels (4.82 mi)
- Elloree Hotels (6.29 mi)
- Harleyville Hotels (18.94 mi)
- Bamberg Hotels (34.78 mi)
- The South Hotels (543.71 mi)
Most Booked Hotels in Santee
- Fairfield Inn & Suites by Marriott Santee
- Holiday Inn Santee by IHG
- Hampton Inn Santee-I-95
- Comfort Inn & Suites Santee
- Best Western Plus Santee Inn
- Travelodge by Wyndham Santee
- Red Roof Inn Santee
- Ramada by Wyndham Santee I-95
- Econo Lodge
- Super 8 by Wyndham Santee
- Tru by Hilton Orangeburg
- Spark by Hilton Orangeburg