Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Santa Ana Vacations

Pack those stellar shades. We have Santa Ana vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Santa Ana – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Santa Ana vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Santa Ana

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Santa Ana vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Santa Ana well.

Top Hotel Deals

See all 600 Hotels in Sonora
Best Western Laos Mar Hotel & Suites

Best Western Laos Mar Hotel & Suites

Paseo Balboa no. 90, Puerto Penasco
2.5 out of 5.0

Situated near the beach, this hotel is within 2 mi (3 km) of Old Port, El Malecon, and Fisherman's Monument. La Madre Square is 1.5 mi (2.4 km) away.

$83

$83
Marinaterra Hotel & Spa

Marinaterra Hotel & Spa

Calle Gabriel Estrada S/n, San Carlos
4.0 out of 5.0

Situated near the airport, this spa hotel is 1.1 mi (1.8 km) from San Carlos Golf Course and within 9 mi (15 km) of Mirador Escenico de San Carlos and Nacapule ...

$65

$65
ibis Hermosillo

ibis Hermosillo

Boulevard Cultura 48, Hermosillo
3.5 out of 5.0

Situated in the entertainment district, this hotel is within a 10-minute walk of Government Center, Sonoran Institute of Culture, and Museo de Arte de Sonora. ...

$23

$23
Peñasco del Sol

Peñasco del Sol

Paseo de las Glorias No 1, Puerto Penasco
4.0 out of 5.0

Located in Puerto Penasco, this beachfront hotel is in the city center and within 2 mi (3 km) of El Malecon and La Madre Square.

$67

$67
Fiesta Americana Hermosillo

Fiesta Americana Hermosillo

Blvd Eusebio Kino 369, Hermosillo
4.5 out of 5.0

Situated near the airport, this hotel is within 3 mi (5 km) of Parque Madero, Hidalgo Square, and Galerias Mall Sonora. Plaza Zaragoza and Museum of Popular ...

$76

$76
Hampton By Hilton Hermosillo

Hampton By Hilton Hermosillo

Paseo Rio Sonora 172, Hermosillo
2.5 out of 5.0

Situated in the business district, this hotel is within a 15-minute walk of Government Center, Galerias Mall Sonora, and Museum of Popular and Indigenous Cultures ...

$52

$52
Hotel Colonial Hermosillo

Hotel Colonial Hermosillo

Vado Del Rio No 9, Villa de Seris, Hermosillo
4.0 out of 5.0

Located in the heart of Hermosillo, this hotel is within a 10-minute walk of Government Center, Sonoran Institute of Culture, and Galerias Mall Sonora. Cerro ...

$40

$40
City Express Hermosillo

City Express Hermosillo

Blvd. Río Sonora Norte No. 96, Hermosillo
2.5 out of 5.0

Situated in Hermosillo, this eco-friendly hotel is within a 15-minute walk of Government Center, Museum of Popular and Indigenous Cultures of Sonora, and Metropolitan ...

$39

$39
Gamma by Fiesta Inn Ciudad Obregón

Gamma by Fiesta Inn Ciudad Obregón

Av. Miguel Alemán y Tetabiate, Ciudad Obregon
4.5 out of 5.0

Situated in the business district, this hotel is within 1 mi (2 km) of Fatima Church and Los Pioneros Park. Plaza Tutuli Shopping Center and Tomas Oroz Gaytan ...

$37

$37
Hotel Araiza San Luis

Hotel Araiza San Luis

Av Madero y Calle 18 1800, San Luis Rio Colorado
4.0 out of 5.0

Situated in San Luis Rio Colorado, this hotel is 1.6 mi (2.5 km) from Garita Entrance to Mexico and 1.9 mi (3 km) from San Luis Lakes State Park. Forest of the ...