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Choose from 3190 Salem Hotel Deals

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $97 per night from May 24 to May 25
$97
per night
May 24 - May 25
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,001 reviews)
"Perfect location for my needs. Quiet. Would stay there again."

Reviewed on Apr 29, 2024

Comfort Inn & Suites Clemson - University Area
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $169 per night from May 12 to May 13
$169
per night
May 12 - May 13
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.8/10 Exceptional! (264 reviews)
"Absolutely beautiful hotel…very recommendable"

Reviewed on May 6, 2024

The Shepherd Hotel Downtown Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $99 per night from May 11 to May 12
$99
per night
May 11 - May 12
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,004 reviews)
"This is great hotel close to Clemson University. Rooms very clean bed very comfortable. Good breakfast options with waffles, sausage, cheese omelette, sausage biscuits and more. No complaints. Will stay again."

Reviewed on Apr 22, 2024

Inn @ Clemson
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 21 min drive from Lake Keowee
The price is $109 per night from May 11 to May 12
$109
per night
May 11 - May 12
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (591 reviews)
"The facility felt like being at home. So clean and very welcoming. We will return."

Reviewed on May 3, 2024

Lakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $105 per night from May 13 to May 14
$105
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (775 reviews)
"Great service. Need better fitness center."

Reviewed on May 3, 2024

Best Western Plus Clemson Hotel & Conference Center
Holiday Inn Express Brevard City Center, an IHG Hotel
Holiday Inn Express Brevard City Center, an IHG Hotel
2.5 out of 5
185 Old Hendersonville Hwy, Brevard, NC
  • 1 hour drive from Lake Keowee
The price is $120 per night from Jun 2 to Jun 3
$120
per night
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Brevard. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (360 reviews)
"Awesome hotel."

Reviewed on May 2, 2024

Holiday Inn Express Brevard City Center, an IHG Hotel
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3 out of 5
240 Madren Center Drive, Clemson, SC
  • 26 min drive from Lake Keowee
The price is $149 per night from May 14 to May 15
$149
per night
May 14 - May 15
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, an outdoor pool, and a golf course. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (725 reviews)
"Favorite place to stay in Clemson! The staff are very friendly and the grounds are beautiful! I can’t wait until our next stay!"

Reviewed on Apr 29, 2024

Clemson University's James F. Martin Inn
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 25 min drive from Lake Keowee
The price is $129 per night from May 13 to May 14
$129
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (776 reviews)
"Very coneveniet"

Reviewed on Apr 23, 2024

Holiday Inn Express & Suites Clemson, an IHG Hotel
The Inn at Patrick Square
The Inn at Patrick Square
3.5 out of 5
115 Market Street, Clemson, SC
  • 28 min drive from Lake Keowee
The price is $149 per night from May 14 to May 15
$149
per night
May 14 - May 15
Stay at this hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (611 reviews)
I like this place
"Fantastic Hotel, Spotlessly clean"

Reviewed on May 6, 2024

The Inn at Patrick Square
The Abernathy of Clemson
The Abernathy of Clemson
4 out of 5
157 Old Greenville Hwy, Clemson, SC
  • 24 min drive from Lake Keowee
The price is $149 per night from May 19 to May 20
$149
per night
May 19 - May 20
Stay at this 4-star business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (388 reviews)
"Great bartender"

Reviewed on May 3, 2024

The Abernathy of Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 21 min drive from Lake Keowee
The price is $105 per night from May 31 to Jun 1
$105
per night
May 31 - Jun 1
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (566 reviews)
"Clean and comfortable. Seems newer than some of the other Clemson area properties. Good water pressure and updated bathroom. Allows dogs and seems walkable to Death Valley. Across the street from Clemsons rec area by the lake."

Reviewed on Apr 28, 2024

Tru by Hilton Seneca Clemson
Highlander Mountain House
Highlander Mountain House
3.5 out of 5
270 Main Street, Highlands, NC
  • 1 hour drive from Lake Keowee
The price is $190 per night from May 8 to May 9
$190
per night
May 8 - May 9
Stay at this inn in Highlands. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Highlands Playhouse and Highlands Art Gallery are located ...
8.4/10 Very Good! (98 reviews)
Charming Retreat in the Heart of Blue Ridge
"Highlander Mountain House in the Blue Ridge mountains is just divine! The design and decor are so charming, from the cozy rooms to the lovely common areas. I can't get enough of the warm ambiance throughout the property. And let's talk about the location – being near downtown Highlands is such a ..."

Reviewed on Apr 1, 2024

Highlander Mountain House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Salem

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Salem.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Salem’s 3,190 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Salem hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Salem. No matter your reason for visiting Salem, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Salem hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Salem for as low as $65.

How many hotels are there in Salem?

With over 3,190 hotels in Salem, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Salem?

Finding a cheap car rental deal in Salem is as easy as scoring cheap hotels in Salem. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Salem now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Salem right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.