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Choose from 611 Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
  • 44 min drive from Neal Smith National Wildlife Refuge
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,081 reviews)
Amazing is not the word for this place! Staff was amazing! Totally excited our expectations

Reviewed on Jan 26, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
  • 53 min drive from Neal Smith National Wildlife Refuge
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (702 reviews)
Room a little dirty

Reviewed on Jan 22, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,010 reviews)
Comfy beds, very nice staff, loved that my dog was welcome there. Will definitely stay there again.

Reviewed on Jan 26, 2026

Home2 Suites by Hilton Des Moines at Drake University
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,739 reviews)
Nice

Reviewed on Jan 25, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
  • 44 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.6/10 Exceptional! (1,030 reviews)
The room was nice. Very romantic. The heat in the room, like literal heater was very good when it was so cold outside.

Reviewed on Jan 23, 2026

Des Lux Hotel
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St Des Moines IA
  • 42 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
8/10 Very Good! (1,020 reviews)
Wonderful like always

Reviewed on Jan 24, 2026

Embassy Suites Hotel Des Moines Downtown
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Friendly, helpful staff

Reviewed on Jan 24, 2026

Hampton Inn Des Moines-Airport
Quality Inn & Suites Des Moines - Merle Hay Road

Quality Inn & Suites Des Moines - Merle Hay Road

2.5 out of 5
4995 Merle Hay Rd Des Moines IA
  • 53 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,009 reviews)
It was good the service was good the halways where kinda cool but when we got into the pool it was nice and earm and woke up and breakfast was nice and good too

Reviewed on Jan 25, 2026

Quality Inn & Suites Des Moines - Merle Hay Road
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

4 out of 5
206 6th Ave. Des Moines IA
  • 43 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar in our reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
Beautiful, clean rooms. Excellent customer service.

Reviewed on Jan 25, 2026

Surety Hotel, Autograph Collection
Holiday Inn Hotel & Suites Des Moines - Northwest by IHG

Holiday Inn Hotel & Suites Des Moines - Northwest by IHG

3 out of 5
4800 Merle Hay Rd Urbandale IA
  • 53 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Urbandale. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
Perfect friendly beautiful warm place to stay very quiet

Reviewed on Jan 24, 2026

Holiday Inn Hotel & Suites Des Moines - Northwest by IHG
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,000 reviews)
Room was great

Reviewed on Jan 22, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

2.5 out of 5
120 Sw Water St Des Moines IA
  • 42 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,001 reviews)
The room was clean and comfortable. The location was wonderful

Reviewed on Jan 20, 2026

Hampton Inn & Suites Des Moines Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Prairie City

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How many hotels are there in Prairie City?

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