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Hotels in Prairie City

Choose from 616 Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
  • 44 min drive from Neal Smith National Wildlife Refuge
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,093 reviews)
Toilet wouldn’t flush, shower wouldn’t drain, valet was incredibly slow, front desk wasn’t very nice. The best part of the stay was the coffee shop and their employees.

Reviewed on Mar 15, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,005 reviews)
It was very nice room and clean and the bed was very comfy and nice after long day driving

Reviewed on Mar 17, 2026

Home2 Suites by Hilton Des Moines at Drake University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
  • 44 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,042 reviews)
This hotel is top notch. We enjoyed our stay. Everything was clean, the decor is so fun, and the staff was very accommodating. The breakfast buffet offered a wide variety, and was easy to access each morning. The only complaint was the parking was across the street in a garage that was not owned ...

Reviewed on Mar 16, 2026

Des Lux Hotel
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
  • 44 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,001 reviews)
Clean room, bar was stocked well, air conditioning wouldn't work quite right it was hot in our room.

Reviewed on Mar 12, 2026

Holiday Inn Downtown - Mercy Area by IHG
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,754 reviews)
The room didn't really have a closet to hang clothes. And the breakfast buffet did not have any meat which was very disappointing.

Reviewed on Mar 15, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
  • 53 min drive from Neal Smith National Wildlife Refuge
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (750 reviews)
When I went to my room, it hadn’t been cleaned. They wanted to refund money. I told them it was after midnight and we needed a room. They were able to get us two separate rooms instead with the second one for free. I thought the furniture and carpet were very outdated. Carpet throughout hotel had ...

Reviewed on Mar 16, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

3.5 out of 5
101 E Locust St Des Moines IA
  • 42 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,002 reviews)
Everything was great.

Reviewed on Mar 16, 2026

Embassy Suites Hotel Des Moines Downtown
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
  • 47 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,010 reviews)
Clean room and helpful staff.

Reviewed on Mar 16, 2026

Hampton Inn Des Moines-Airport
Quality Inn & Suites Des Moines - Merle Hay Road

Quality Inn & Suites Des Moines - Merle Hay Road

2.5 out of 5
4995 Merle Hay Rd Des Moines IA
  • 53 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,002 reviews)
The staff is excellent!

Reviewed on Mar 14, 2026

Quality Inn & Suites Des Moines - Merle Hay Road
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

3 out of 5
418 6th Avenue Des Moines IA
  • 43 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour health club. Our guests praise the breakfast and the ...
8.2/10 Very Good! (1,003 reviews)
Room was clean and orderly. Bed and pillows were quite uncomfortable and the towels were very rough and the water is very hard. Light breakfast was good.

Reviewed on Mar 13, 2026

Hyatt Place Des Moines/Downtown
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

4 out of 5
206 6th Ave. Des Moines IA
  • 43 min drive from Neal Smith National Wildlife Refuge
Stay at this hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar in our reviews. Popular ...
9.4/10 Exceptional! (1,001 reviews)
Nice staff and very nice room

Reviewed on Mar 16, 2026

Surety Hotel, Autograph Collection
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

3 out of 5
201 E. Locust Street Des Moines IA
  • 42 min drive from Neal Smith National Wildlife Refuge
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
Was awesome. Staff was friendly and contential breakfast was good. Lots of variety. Pool was stocked with towels and hot tub was a hit with my family.

Reviewed on Mar 16, 2026

Staybridge Suites Des Moines Downtown by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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