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Hotels in Carlisle

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Choose from 557 Carlisle Hotel Deals

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA, 50315
  • 17 min drive from MercyOne Carlisle Family Medicine
The price is $60 per night from Feb 5 to Feb 6
$60
per night
Feb 5 - Feb 6
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
4.1/5 Very Good! (1,024 reviews)
"Comfortable beds, clean, microwave/fridge in room & a good breakfast"

Reviewed on Jan 27, 2023

Days Inn & Suites by Wyndham Des Moines Airport
Embassy Suites Hotel Des Moines Downtown
Embassy Suites Hotel Des Moines Downtown
3.5 out of 5
101 E Locust St, Des Moines, IA, 50309
  • 18 min drive from MercyOne Carlisle Family Medicine
The price is $115 per night from Feb 5 to Feb 6
$115
per night
Feb 5 - Feb 6
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
4.1/5 Very Good! (1,054 reviews)
"The breakfast was excellent"

Reviewed on Jan 29, 2023

Embassy Suites Hotel Des Moines Downtown
La Quinta by Wyndham Altoona Des Moines
La Quinta by Wyndham Altoona Des Moines
2.5 out of 5
1785 11th Street NW, Altoona, IA, 50009
  • 26 min drive from MercyOne Carlisle Family Medicine
The price is $61 per night from Feb 5 to Feb 6
$61
per night
Feb 5 - Feb 6
Stay at this business-friendly hotel in Altoona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
4.5/5 Wonderful! (1,045 reviews)
"This place is clean and comfortable."

Reviewed on Jan 24, 2023

La Quinta by Wyndham Altoona Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA, 50309
  • 19 min drive from MercyOne Carlisle Family Medicine
The price is $127 per night from Feb 9 to Feb 10
$127
per night
Feb 9 - Feb 10
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast, and room service. Popular attractions The Temple for Performing Arts and Des Moines ...
4.7/5 Exceptional! (347 reviews)
Great
"Love to stay at this hotel, close to a lot restaurants and venues that we attend."

Reviewed on Jan 29, 2023

Hotel Fort Des Moines, Curio Collection by Hilton
Des Lux Hotel
Des Lux Hotel
3.5 out of 5
800 Locust St, Des Moines, IA, 50309
  • 19 min drive from MercyOne Carlisle Family Medicine
The price is $151 per night from Jan 31 to Feb 1
$151
per night
Jan 31 - Feb 1
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff ...
4.7/5 Exceptional! (1,030 reviews)
"Love this place! Service is excellent. Room was very original and thoughtfully put together. Location was excellent with many restaurants, ads and shops nearby. Would definitely stay here again."

Reviewed on Jan 27, 2023

Des Lux Hotel
Adventureland Inn
Adventureland Inn
2.5 out of 5
3200 Adventureland Dr, Altoona, IA, 50009
  • 25 min drive from MercyOne Carlisle Family Medicine
The price is $114 per night from Jan 31 to Feb 1
$114
per night
Jan 31 - Feb 1
Stay at this family-friendly hotel in Altoona. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
3.8/5 Good! (561 reviews)
Family friendly
"Great stay for the family. Kids loved the pool and was nice to be able to see them from the room while they swam. Service was great, we left an important item in our room after we checked out and they call promptly and got it returned to us before leaving town. Excellent stay."

Reviewed on Jan 29, 2023

Adventureland Inn
Fairfield Inn and Suites by Marriott Des Moines West
Fairfield Inn and Suites by Marriott Des Moines West
2.5 out of 5
7225 Vista Dr, West Des Moines, IA, 50266
  • 39 min drive from MercyOne Carlisle Family Medicine
The price is $84 per night from Feb 23 to Feb 24
$84
per night
Feb 23 - Feb 24
Stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
4.4/5 Excellent! (1,042 reviews)
"Loved how welcoming this place is. Not only for me but for fur babies"

Reviewed on Jan 29, 2023

Fairfield Inn and Suites by Marriott Des Moines West
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA, 50131
  • 36 min drive from MercyOne Carlisle Family Medicine
The price is $94 per night from Feb 5 to Feb 6
$94
per night
Feb 5 - Feb 6
Stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
4.4/5 Excellent! (1,036 reviews)
"Fun place to stay for families! Loved that our room had a built in fire place."

Reviewed on Jan 26, 2023

Stoney Creek Hotel Des Moines - Johnston
SpringHill Suites Des Moines West
SpringHill Suites Des Moines West
3 out of 5
1236 Jordan Creek Pkwy, West Des Moines, IA, 50266
  • 40 min drive from MercyOne Carlisle Family Medicine
The price is $96 per night from Feb 5 to Feb 6
$96
per night
Feb 5 - Feb 6
Stay at this 3-star business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
4.2/5 Very Good! (1,017 reviews)
"Nice property to stay at"

Reviewed on Jan 22, 2023

SpringHill Suites Des Moines West
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA, 50325
  • 36 min drive from MercyOne Carlisle Family Medicine
The price is $104 per night from Feb 5 to Feb 6
$104
per night
Feb 5 - Feb 6
Stay at this 3-star business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms and the overall value ...
4.7/5 Exceptional! (1,377 reviews)
"Nice hotel, breakfast wasn't fantastic but had variety. We will stay again some time! Parking lot could have been a little cleaner."

Reviewed on Jan 29, 2023

Wildwood Lodge
Hyatt Place Des Moines/Downtown
Hyatt Place Des Moines/Downtown
3 out of 5
418 6th Avenue, Des Moines, IA, 50309
  • 19 min drive from MercyOne Carlisle Family Medicine
The price is $104 per night from Feb 5 to Feb 6
$104
per night
Feb 5 - Feb 6
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and onsite parking. Our guests praise the breakfast and the comfy ...
4.1/5 Very Good! (1,016 reviews)
"Great location and friendly front desk personnel! The room could use better cleaning- it was quite dusty."

Reviewed on Jan 23, 2023

Hyatt Place Des Moines/Downtown
Hampton Inn & Suites Des Moines Downtown
Hampton Inn & Suites Des Moines Downtown
2.5 out of 5
120 Sw Water St, Des Moines, IA, 50309
  • 18 min drive from MercyOne Carlisle Family Medicine
The price is $135 per night from Feb 9 to Feb 10
$135
per night
Feb 9 - Feb 10
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff ...
4.4/5 Excellent! (1,005 reviews)
"good"

Reviewed on Dec 31, 2022

Hampton Inn & Suites Des Moines Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Carlisle

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Carlisle hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Carlisle.

Choosing the right hotel in Iowa has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Carlisle’s 557 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $58. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Carlisle hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Carlisle. No matter your reason for visiting Carlisle, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Carlisle hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Carlisle for as low as $58.

How many hotels are there in Carlisle?

With over 557 hotels in Carlisle, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $58.

How to find cheap car rentals in Carlisle?

Finding a cheap car rental deal in Carlisle is as easy as scoring cheap hotels in Carlisle. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Carlisle now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Carlisle right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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