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Otay Mesa Vacation Packages

Otay Mesa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Price was $545, price is now $352 per person
$352
per person
Dec 14 - Dec 18
found 20 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
Carmel Valley
Price was $2,203, price is now $1,538 per person
$1,538
per person
Dec 17 - Dec 22
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Diego (SAN)
Book a stay at this luxury hotel in San Diego. Enjoy free WiFi, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Torrey Pines Golf Course and Del Mar Racetrack are located nearby.
Carlsbad Inn Beach Resort

Carlsbad Inn Beach Resort

4 out of 5
Carlsbad Village
Price was $1,169, price is now $838 per person
$838
per person
Dec 17 - Dec 22
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Diego (SAN)
Book a stay at this beach aparthotel in Carlsbad. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions LEGOLAND® California and Carlsbad State Beach are located nearby.
Ocean Villas of Carlsbad

Ocean Villas of Carlsbad

3 out of 5
Carlsbad Village
Price was $1,830, price is now $1,042 per person
$1,042
per person
Dec 3 - Dec 8
found 20 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach villa in Carlsbad. Enjoy free WiFi, a private beach, and parking (surcharge). Popular attractions LEGOLAND® California and Carlsbad State Beach are located nearby.
Los Bungalows

Los Bungalows

2.5 out of 5
Seacoast
Price was $718, price is now $478 per person
$478
per person
Dec 3 - Dec 8
found 23 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Bay and Las Americas Premium Outlets are located nearby.
Alila Marea Beach Resort Encinitas, a Hyatt Luxury Resort

Alila Marea Beach Resort Encinitas, a Hyatt Luxury Resort

5 out of 5
Price was $1,357, price is now $923 per person
$923
per person
Dec 16 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Diego (SAN)
Book a stay at this luxury resort in Encinitas. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attractions LEGOLAND® California and Moonlight State Beach are located nearby.
Murrieta Hot Springs Resort

Murrieta Hot Springs Resort

4 out of 5
Murrieta Hot Springs
Price was $1,226, price is now $840 per person
$840
per person
Dec 1 - Dec 6
found 1 day ago
Roundtrip flight included
Portland (PDX) to San Diego (SAN)
Book a stay at this beach hotel in Murrieta. Enjoy free WiFi, free parking, and 15 outdoor pools. Popular attractions Old Town Temecula Community Theater and Paint a Dream are located nearby.
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
Mission Bay
Price was $661, price is now $459 per person
$459
per person
Dec 3 - Dec 8
found 23 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.

3-4 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Hotel Z

Hotel Z

3 out of 5
Downtown San Diego
Save 100% on your flight
Price was $675, price is now $428 per person
$428
per person
Dec 3 - Dec 6
found 9 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
Carmel Valley
Price was $1,310, price is now $811 per person
$811
per person
Dec 14 - Dec 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $720, price is now $441 per person
$441
per person
Dec 2 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Diego (SAN)
Glorietta Bay Inn Coronado Island

Glorietta Bay Inn Coronado Island

3.5 out of 5
Historic Downtown Coronado
Save 100% on your flight
Price was $825, price is now $543 per person
$543
per person
Dec 2 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to San Diego (SAN)

5-7 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $779, price is now $466 per person
$466
per person
Dec 17 - Dec 24
found 4 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
Carmel Valley
Price was $2,203, price is now $1,538 per person
$1,538
per person
Dec 17 - Dec 22
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Diego (SAN)
Ocean Villas of Carlsbad

Ocean Villas of Carlsbad

3 out of 5
Carlsbad Village
Price was $1,830, price is now $1,042 per person
$1,042
per person
Dec 3 - Dec 8
found 20 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Los Bungalows

Los Bungalows

2.5 out of 5
Seacoast
Price was $718, price is now $478 per person
$478
per person
Dec 3 - Dec 8
found 23 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)

Cheap Hotel Deals in Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 out of 5
2296 Niels Bohr Ct San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Opens in a new windowHoliday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Opens in a new windowWyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Opens in a new windowHard Rock Hotel San Diego
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Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Opens in a new windowHandlery Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Opens in a new windowParadise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Opens in a new windowBest Western Seven Seas
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Opens in a new windowSheraton San Diego Resort
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Dec 1 - Sat, Dec 5
SFO
San Francisco Intl.
SAN
San Diego Intl.
$38 Roundtrip, found 1 hour ago
$38
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Tue, Dec 1 from San Francisco Intl. to San Diego Intl., returning Sat, Dec 5, priced at $38 found 1 hour ago
Frontier Airlines
Thu, Nov 26 - Tue, Dec 1
DEN
Denver Intl.
SAN
San Diego Intl.
$67 Roundtrip, found 20 hours ago
$67
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Thu, Nov 26 from Denver Intl. to San Diego Intl., returning Tue, Dec 1, priced at $67 found 20 hours ago
Southwest Airlines
Sat, Dec 5 - Sat, Dec 5
PDX
Portland Intl.
SAN
San Diego Intl.
$115 Roundtrip, found 8 hours ago
$115
Roundtrip
found 8 hours ago
Select Southwest Airlines flight, departing Sat, Dec 5 from Portland Intl. to San Diego Intl., returning Sat, Dec 5, priced at $115 found 8 hours ago
Alaska Airlines
Wed, Dec 2 - Wed, Dec 9
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$131 Roundtrip, found 6 hours ago
$131
Roundtrip
found 6 hours ago
Select Alaska Airlines flight, departing Wed, Dec 2 from Seattle - Tacoma Intl. to San Diego Intl., returning Wed, Dec 9, priced at $131 found 6 hours ago