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Otay Mesa Vacation Packages

Otay Mesa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town

3 out of 5
Old Town San Diego
Save 100% on your flight
Price was $631, price is now $403 per person
$403
per person
May 7 - May 12
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Port of San Diego and San Diego Zoo are located nearby.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,060, price is now $619 per person
$619
per person
Apr 21 - Apr 25
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Kona Kai San Diego

Kona Kai San Diego

4 out of 5
Point Loma
Save 100% on your flight
Price was $960, price is now $561 per person
$561
per person
May 7 - May 12
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,025, price is now $660 per person
$660
per person
Apr 21 - Apr 25
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Los Bungalows

Los Bungalows

2.5 out of 5
Save 100% on your flight
Price was $1,214, price is now $788 per person
$788
per person
Apr 16 - Apr 23
found 1 day ago
Roundtrip flight included
Salt Lake City (SLC) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions Las Americas Premium Outlets and Imperial Beach are located nearby.
Estancia La Jolla Hotel & Spa

Estancia La Jolla Hotel & Spa

4 out of 5
La Jolla Farms
Save 100% on your flight
Price was $1,107, price is now $749 per person
$749
per person
Apr 24 - Apr 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this spa hotel in La Jolla. Enjoy a full-service spa, 4 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Torrey Pines Golf Course and La Jolla Beach are located nearby.
The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar

3 out of 5
Downtown San Diego
Save 100% on your flight
Price was $954, price is now $675 per person
$675
per person
Apr 21 - Apr 25
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $654, price is now $469 per person
$469
per person
Apr 24 - Apr 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this aparthotel in San Diego. Enjoy free WiFi, a rooftop terrace, and a 24-hour fitness center. Popular attractions Petco Park and Port of San Diego are located nearby.

3-4 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Hyland Inn Near Legoland

Hyland Inn Near Legoland

3 out of 5
Olde Carlsbad
Price was $523, price is now $349 per person
$349
per person
Apr 30 - May 3
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,060, price is now $619 per person
$619
per person
Apr 21 - Apr 25
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,025, price is now $660 per person
$660
per person
Apr 21 - Apr 25
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Estancia La Jolla Hotel & Spa

Estancia La Jolla Hotel & Spa

4 out of 5
La Jolla Farms
Save 100% on your flight
Price was $1,107, price is now $749 per person
$749
per person
Apr 24 - Apr 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)

5-7 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $982, price is now $542 per person
$542
per person
Apr 24 - Apr 29
found 2 days ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar

3 out of 5
Downtown San Diego
Save 100% on your flight
Price was $1,631, price is now $922 per person
$922
per person
Apr 20 - Apr 27
found 24 hours ago
Roundtrip flight included
Salt Lake City (SLC) to San Diego (SAN)
Kona Kai San Diego

Kona Kai San Diego

4 out of 5
Point Loma
Save 100% on your flight
Price was $960, price is now $561 per person
$561
per person
May 7 - May 12
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Ocean Park Inn

Ocean Park Inn

3 out of 5
Pacific Beach
Save 100% on your flight
Price was $1,011, price is now $598 per person
$598
per person
May 7 - May 12
found 3 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)

Cheap Hotel Deals in Otay Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Opens in a new windowParadise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
Opens in a new windowBest Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Opens in a new windowHard Rock Hotel San Diego
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Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Opens in a new windowHandlery Hotel
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
Opens in a new windowThe Sofia Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
Opens in a new windowManchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Apr 15 - Sat, Apr 18
DEN
Denver Intl.
SAN
San Diego Intl.
$58 Roundtrip, found 13 hours ago
$58
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Wed, Apr 15 from Denver Intl. to San Diego Intl., returning Sat, Apr 18, priced at $58 found 13 hours ago
Frontier Airlines
Wed, May 13 - Sat, May 16
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$66 Roundtrip, just found
$66
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, May 13 from Dallas-Fort Worth Intl. to San Diego Intl., returning Sat, May 16, priced at $66 just found
Frontier Airlines
Wed, Jul 29 - Tue, Aug 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$96 Roundtrip, found 5 days ago
$96
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Jul 29 from San Francisco Intl. to San Diego Intl., returning Tue, Aug 4, priced at $96 found 5 days ago
Delta
Sat, Apr 25 - Sat, May 9
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$139 Roundtrip, just found
$139
Roundtrip
just found
Select Delta flight, departing Sat, Apr 25 from Seattle - Tacoma Intl. to San Diego Intl., returning Sat, May 9, priced at $139 just found