Search Deals onOtay Mesa Vacation Packages
Otay Mesa Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Sand Castle Inn
Save 100% on your flight
Price was $592, price is now $399 per person
$399
per person
Oct 6 - Oct 10
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Bay and Las Americas Premium Outlets are located nearby.

The Sofia Hotel
Downtown San Diego
Save 100% on your flight
Price was $814, price is now $509 per person
$509
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 3.5-star historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

San Diego Mission Bay Resort
Save 100% on your flight
Price was $1,040, price is now $668 per person
$668
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 4-star beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.

Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
Price was $769, price is now $497 per person
$497
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this spa hotel in Escondido. Enjoy free parking, 8 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in our reviews. Popular attractions The Oaks Course and Cal-a-vie are located nearby.

Hampton Inn & Suites San Diego Seaworld
Point Loma
Save 100% on your flight
Price was $723, price is now $479 per person
$479
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission Beach are located nearby.

Estancia La Jolla Hotel & Spa
La Jolla Farms
Save 100% on your flight
Price was $1,457, price is now $974 per person
$974
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 4-star spa hotel in La Jolla. Enjoy a full-service spa, 4 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Torrey Pines Golf Course and La Jolla Beach are located nearby.

Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $956, price is now $640 per person
$640
per person
Oct 12 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 4-star hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

The Dana on Mission Bay
Save 100% on your flight
Price was $886, price is now $612 per person
$612
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
3-4 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



Cheap Hotel Deals in Otay Mesa

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Save an average of 15% on thousands of hotels when you're signed in

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...

Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave, Coronado, CA
Stay at this 4-star beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff and the property condition ...

Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...

Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Mon, Sep 29 - Thu, Oct 2
SFO
San Francisco Intl.
SAN
San Diego Intl.
$74 Roundtrip, found 1 day ago
$74
Roundtrip
found 1 day ago

Sat, Sep 13 - Tue, Sep 16
DEN
Denver Intl.
SAN
San Diego Intl.
$85 Roundtrip, found 18 hours ago
$85
Roundtrip
found 18 hours ago

Wed, Nov 5 - Wed, Nov 5
ORD
O'Hare Intl.
SAN
San Diego Intl.
$133 Roundtrip, found 2 days ago
$133
Roundtrip
found 2 days ago

Wed, Oct 15 - Tue, Oct 21
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$149 Roundtrip, just found
$149
Roundtrip
just found
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