Search Deals onMain Street Cultural District Vacation Packages
Main Street Cultural District Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Motel 6 West Des Moines, IA
Price was $463, price is now $419 per person
$419
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Jordan Creek Town Center and Des Moines Golf & Country Club are located nearby.

AmericInn by Wyndham Des Moines Airport
Price was $584, price is now $488 per person
$488
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Air Lanes Bowling Center are located nearby.

Hotel Fort Des Moines, Curio Collection by Hilton
Price was $829, price is now $705 per person
$705
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

AmericInn by Wyndham Ankeny/Des Moines
Price was $567, price is now $492 per person
$492
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Ankeny. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Adventureland and Prairie Meadows Racetrack and Casino are located nearby.

Hampton Inn & Suites Des Moines Downtown
Price was $703, price is now $619 per person
$619
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Residence Inn Des Moines Downtown
Price was $675, price is now $597 per person
$597
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 3-star hotel in Des Moines. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Des Moines Marriott Downtown
Price was $725, price is now $650 per person
$650
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Des Moines. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular attractions Casey's Center and Iowa State Fairgrounds are located nearby.

Sleep Inn & Suites Pleasant Hill - Des Moines
Price was $550, price is now $495 per person
$495
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Book a stay at this business-friendly hotel in Pleasant Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Iowa State Fairgrounds and Adventureland are located nearby.

Hampton Inn Des Moines-Airport
Price was $638, price is now $578 per person
$578
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Casey's Center and Air Lanes Bowling Center are located nearby.

My Place Hotel - Altoona/Des Moines, IA
Price was $507, price is now $460 per person
$460
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Altoona. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Prairie Meadows Racetrack and Casino and Adventureland are located nearby.

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
Price was $585, price is now $532 per person
$532
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 3-star business-friendly hotel in Ankeny. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Adventureland and Prairie Meadows Racetrack and Casino are located nearby.

Wildwood Lodge
Price was $742, price is now $676 per person
$676
per person
Nov 22 - Nov 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jordan Creek Town Center and Clive Aquatic Center are located nearby.
3-4 Night Vacations in Main Street Cultural District
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Main Street Cultural District
Price found within the past 48 hours. Click for updated prices.



Main Street Cultural District Last Minute Hotel Deals

Gateway Hotel and Conference Center at Iowa State University
2100 Green Hills Drive, Ames, IA
Stay at this 3-star business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...

Comfort Inn and Suites Ames near ISU Campus
603 South 16th Street, Ames, IA
Book a stay at this golf hotel in Ames. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in ...

Country Inn & Suites by Radisson, Ames, IA
2605 Se 16th St, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

SpringHill Suites by Marriott Ames
1810 SE 16TH STREET, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

GrandStay Hotel & Suites
1606 S Kellogg Ave, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Microtel Inn & Suites by Wyndham Ames
2216 Se 16th St, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Quality Inn & Suites Ames Conference Center Near ISU Campus
2601 E 13th St, Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Octagon Center for the Arts and Main ...

AmericInn by Wyndham Ames
2507 SE 16th St., Ames, IA
Book a stay at this business-friendly hotel in Ames. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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