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Hotels in Lignumvitae Key Botanical State Park

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Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
  • 10 min drive from Indian Key Historic State Park
Book a stay at this luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,320 reviews)
"Cheeca Lodge is my absolute favorite place in The Keys The property is gorgeous, I love the amenities, the complimentary kayaking, bikes & champagne for Mother’s Day was such a nice touch The rooms are so cozy, just love it there. Ask for Rob at the pool bar, he makes a great drink!"

Reviewed on Jun 4, 2026

Cheeca Lodge & Spa
Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
  • 14 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Islamorada. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the pool in our reviews. ...
9.2/10 Wonderful! (1,746 reviews)
"A beautiful place to stay on the Florida Keys! The staff were all so nice, breakfast was good, and the views were unbeatable. We would definitely consider returning!"

Reviewed on Jun 7, 2026

Chesapeake Beach Resort
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
  • 41 min drive from Indian Key Historic State Park
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,011 reviews)
"This is really neat and a unique find. The dinner at salt and ash we had was amazing! We were upgraded to a villa and it was decent but the downstairs bathroom was locked and it needed some better cleaning in the bathrooms upstairs and towel racks!!! It wasn’t horrible, but not the best…. I didn’t ..."

Reviewed on Jun 3, 2026

Hawks Cay Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
  • 54 min drive from Indian Key Historic State Park
Stay at this hotel in Key Largo. Enjoy free WiFi, a marina, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,384 reviews)
"We had a great stay! The room was very clean and well maintained when we arrived. The staff was friendly, helpful, and made check-in and check-out easy. The air conditioning worked perfectly, which was especially important in the Florida heat. We also appreciated having a kitchen available—it was ..."

Reviewed on Jun 7, 2026

Waterside Suites & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
  • 46 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,080 reviews)
"Room was clean . Bed was comfortable the only complaint I have is the walls are definitely thin so you will have to listen to your neighbors conversation and hope they go to sleep at a decent time."

Reviewed on Jun 7, 2026

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
  • 10 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,037 reviews)
"Just a solid spot"

Reviewed on Jun 6, 2026

Islander Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
  • 24 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Long Key. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,303 reviews)
"Beautiful views from room, an abundance of ways to relax whether poolside or by the ocean. Spacious rooms & wide entryways for luggage were also much appreciated."

Reviewed on Jun 7, 2026

Lime Tree Bay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
  • 5 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Islamorada. Enjoy 2 restaurants, a private beach, and 3 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,298 reviews)
"Un viaje familiar y fue expectacular."

Reviewed on Jun 7, 2026

Amara Cay Resort
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy Key Largo FL
  • 53 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,755 reviews)
"The place was nice. I especially loved how convenient and close Snooks restaurant was."

Reviewed on Jun 5, 2026

Bayside Inn Key Largo
Creekside Inn

Creekside Inn

2.5 out of 5
90611 Old Highway Tavernier FL
  • 31 min drive from Indian Key Historic State Park
Stay at this motel in Tavernier. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,003 reviews)
"Clean room, friendly staff, cold ac and plenty of parking. Really like that this place is on the water."

Reviewed on Jun 2, 2026

Creekside Inn
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway Key Largo FL
  • 48 min drive from Indian Key Historic State Park
Book a stay at this luxury resort in Key Largo. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,007 reviews)
"If you are looking for a beautiful beach, comfortable stay, and convenient amenities… this is the best place in the Keys! We will definitely be returning!"

Reviewed on Jun 6, 2026

Playa Largo Resort & Spa, Autograph Collection
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

2 out of 5
99340 Overseas Highway Key Largo FL
  • 52 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and a private beach. Our guests praise the helpful staff and the clean rooms in ...
9/10 Wonderful! (1,012 reviews)
"good location on water but place was very average"

Reviewed on Jun 5, 2026

The Pelican Key Largo Cottages
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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