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Lake Nona Medical City Vacations

Pack those stellar shades. We have Lake Nona Medical City vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Lake Nona Medical City – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Lake Nona Medical City vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Lake Nona Medical City

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Lake Nona Medical City vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Lake Nona Medical City well.

Lake Nona Medical City Flight + Hotel packages

Top Hotel Deals

See all 2,809 Hotels in Lake Nona Medical City
Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona

6955 Lake Nona Boulevard, Orlando
    3.0 out of 5.0
     
     

    Located in Lake Nona, this hotel is within a 10-minute walk of University of Central Florida College of Medicine and VA Medical Center at Lake Nona. Nemours ...

    Courtyard Orlando Lake Nona$94

    Courtyard Orlando Lake Nona$94
    Residence Inn Orlando Lake Nona

    Residence Inn Orlando Lake Nona

    6955 Lake Nona Blvd, Orlando
      3.0 out of 5.0
       
       

      Located in Lake Nona, this hotel is within a 10-minute walk of University of Central Florida College of Medicine and VA Medical Center at Lake Nona. Nemours ...

      Residence Inn Orlando Lake Nona$97

      Residence Inn Orlando Lake Nona$97
      B Resort and Spa located in Disney Springs® Resort Area

      B Resort and Spa located in Disney Springs® Resort Area

      1905 Hotel Plaza Blvd, Lake Buena Vista
        4.0 out of 5.0
         
         

        Walking distance to 2 Walt Disney World Parks

        Caribe Royale All-Suite Hotel & Convention Center

        Caribe Royale All-Suite Hotel & Convention Center

        8101 World Center Dr, Orlando
          4.0 out of 5.0
           
           

          This all-suite hotel with its own convention center is within 6 miles of Walt Disney World Resort, Universal Orlando, SeaWorld, and the Orlando Convention ...

          Caribe Royale All-Suite Hotel & Convention Center$79

          Caribe Royale All-Suite Hotel & Convention Center$79
          Mystic Dunes Resort & Golf Club by Diamond Resorts

          Mystic Dunes Resort & Golf Club by Diamond Resorts

          7600 Mystic Dunes Lane, Kissimmee
            3.5 out of 5.0
             
             

            Set on 600 lushly landscaped acres near Celebration, Mystic Dunes Resort & Golf Club by Diamond Resorts is just 2 miles from Walt Disney World Resort and a short ...

            Mystic Dunes Resort & Golf Club by Diamond Resorts$121

            Mystic Dunes Resort & Golf Club by Diamond Resorts$121
            Holiday Inn Resort Orlando Suites - Waterpark

            Holiday Inn Resort Orlando Suites - Waterpark

            14500 Continental Gateway, Orlando
              3.5 out of 5.0
               
               

              Situated at the entrance to Walt Disney World®, this family-friendly property is just 4.5 miles (7 km) from Disney Springs® area. Epcot is also just a 9-minute ...

              Holiday Inn Resort Orlando Suites - Waterpark$49

              Holiday Inn Resort Orlando Suites - Waterpark$49
              Maingate Lakeside Resort

              Maingate Lakeside Resort

              7769 W Irlo Bronson Memorial Hwy, Kissimmee
                3.0 out of 5.0
                 
                 

                Sprawling across 24 acres in Kissimmee, this Mediterranean-style hotel is located 2 miles from Walt Disney World Resort, and within 17 miles of SeaWorld and ...

                Maingate Lakeside Resort$42

                Maingate Lakeside Resort$42
                Westgate Lakes Resort & Spa Universal Studios Area

                Westgate Lakes Resort & Spa Universal Studios Area

                9500 Turkey Lake Rd, Orlando
                  4.0 out of 5.0
                   
                   

                  The Westgate Lakes Resort & Spa Universal Studios Area is perfect for families and closely located to Orlando's theme parks. SeaWorld® and Universal Studios ...

                  Westgate Lakes Resort & Spa Universal Studios Area$98

                  Westgate Lakes Resort & Spa Universal Studios Area$98
                  Universal's Loews Royal Pacific Resort

                  Universal's Loews Royal Pacific Resort

                  6300 Hollywood Way, Orlando
                    4.0 out of 5.0
                     
                     

                    Located a short walk from Universal Studios Florida™, Universal’s Islands of Adventure™ and Universal CityWalk™, this 1000-room hotel offers Early Park Admission* ...

                    Universal's Loews Royal Pacific Resort$309

                    Universal's Loews Royal Pacific Resort$309
                    Cypress Pointe Resort by Diamond Resorts

                    Cypress Pointe Resort by Diamond Resorts

                    8651 Treasure Cay Lane, Orlando
                      3.0 out of 5.0
                       
                       

                      This family-friendly Orlando hotel is located in the entertainment district, within 3 mi (5 km) of Lake Bryan and Disney Springs®. Disney's Typhoon Lagoon Water ...

                      Cypress Pointe Resort by Diamond Resorts$89

                      Cypress Pointe Resort by Diamond Resorts$89

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.