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Hotels in Central Missouri

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Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,141 reviews)
"we enjoyed the views from the deck and bar watching all the boats on saturday. Our first check in the clerk attempted to charge us a second time for the night, even though it had already been paid through expedia but later that was fixed."

Reviewed on Jun 2, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (828 reviews)
"Very comfortable beds!"

Reviewed on Jun 3, 2026

Baymont by Wyndham Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
  • 14 min drive from Lake of the Ozarks
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (1,002 reviews)
"Staff wonderful, a/c didn't work properly in room and toilet ran constantly. Staff was very helpful and compensating. Property outside of room 5 star. Rooms 3.5 star."

Reviewed on Jun 3, 2026

Margaritaville Lake Resort Lake of the Ozarks
Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

3.5 out of 5
Jefferson City 415 W. McCarty St Jefferson City MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
7/10 Good! (1,018 reviews)
"Room stayed himid and even @ 67 degree it was hot on the 8th floor"

Reviewed on Jun 1, 2026

Capitol Plaza Hotel Jefferson City
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (320 reviews)
"The staff was extra nice room was comfortable Need bars in shower"

Reviewed on Jun 4, 2026

Inn at Grand Glaize
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,861 reviews)
"Was not impressed with the broken down luggage cart, the abbreviated breakfast options, and the general overall appearance of the place. The room was very good."

Reviewed on Jun 4, 2026

Country Inn & Suites by Radisson, Columbia, MO
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,465 reviews)
"The room was fairly clean and was super quiet. We didn’t hear neighbors much in the hallways or around us although the place seemed full. The food at the restaurant wasn’t very good and I would rather go to the market nearby to buy prepared foods next time. But for a good nights sleep highly ..."

Reviewed on Jun 4, 2026

Drury Plaza Hotel Columbia East
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,375 reviews)
"A real nice place to stay. Couldn’t have been better."

Reviewed on Jun 2, 2026

Stoney Creek Hotel Columbia
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,243 reviews)
"Breakfast was fresh and full. Parking was lit and felt safe. Staff was friendly."

Reviewed on Jun 4, 2026

Wingate by Wyndham - Columbia
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,011 reviews)
"The rooms were very clean and the gym was the biggest and best I have ever experienced in my travels. The location was great and the staff were very helpful and courteous!"

Reviewed on Jun 1, 2026

Wyndham Executive Center Columbia
Schmidt's Creek Hotel

Schmidt's Creek Hotel

2 out of 5
5760 Osage Beach Pkwy Osage Beach MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (521 reviews)
"A little dated, but clean. Holes on wall where pictures used to hang. Bathroom vent fan sounded a lot like an old washing machine. Location was good. Parking ample. No microwave, but had coffee pot, safe and mini fridge. Would I stay here again? Maybe."

Reviewed on Jun 5, 2026

Schmidt's Creek Hotel
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,003 reviews)
"Breakfast could have been better and the pool was not opened the whole stay"

Reviewed on Jun 4, 2026

Ramada by Wyndham Columbia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 5,050 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $67. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Central Missouri?

With over 5,050 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.